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Protein
Submitted name:

Putative potassium channel subunit

Gene

Elk

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • potassium ion transport Source: FlyBase
  • regulation of glucose metabolic process Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

Ion channelSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Enzyme and pathway databases

ReactomeiR-DME-1296072. Voltage gated Potassium channels.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative potassium channel subunitImported
Gene namesi
Name:ElkImported
Synonyms:elkImported
ORF Names:CG5076Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0011589. Elk.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei269 – 28921HelicalSequence analysisAdd
BLAST
Transmembranei396 – 42025HelicalSequence analysisAdd
BLAST
Transmembranei484 – 50825HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ23974.
PRIDEiQ23974.

Expressioni

Gene expression databases

BgeeiFBgn0011589.
ExpressionAtlasiQ23974. differential.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0085981.

Structurei

3D structure databases

ProteinModelPortaliQ23974.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini35 – 8955PAS (PER-ARNT-SIM)InterPro annotationAdd
BLAST
Domaini92 – 14453PAC (PAS-associated C-terminal)InterPro annotationAdd
BLAST
Domaini586 – 65065Cyclic nucleotide-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains cyclic nucleotide-binding domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0498. Eukaryota.
ENOG410XPSE. LUCA.
OrthoDBiEOG091G0OXR.
PhylomeDBiQ23974.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR005821. Ion_trans_dom.
IPR003938. K_chnl_volt-dep_EAG/ELK/ERG.
IPR003950. K_chnl_volt-dep_ELK.
IPR001610. PAC.
IPR000014. PAS.
IPR000700. PAS-assoc_C.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PfamiPF00520. Ion_trans. 1 hit.
PF13426. PAS_9. 1 hit.
[Graphical view]
PRINTSiPR01463. EAGCHANLFMLY.
PR01465. ELKCHANNEL.
SMARTiSM00100. cNMP. 1 hit.
SM00086. PAC. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
SSF55785. SSF55785. 1 hit.
TIGRFAMsiTIGR00229. sensory_box. 1 hit.
PROSITEiPS50042. CNMP_BINDING_3. 1 hit.
PS50113. PAC. 1 hit.
PS50112. PAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q23974-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPARKGLLAP QNTFLDTIAT RFDGTHSNFV LGNAQANGNP IVYCSDGFVD
60 70 80 90 100
LTGYSRAQIM QKGCSCHFLY GPDTKEEHKQ QIEKSLSNKM ELKLEVIFYK
110 120 130 140 150
KEGAPFWCLF DIVPIKNEKR DVVLFLASHK DITHTKMLEM NVNEECDSVF
160 170 180 190 200
ALTAALLGAR FRAGSNAGML GLGGLPGLGG PAASDGDTEA GEGNNLDVPA
210 220 230 240 250
GCNMGRRRSR AVLYQLSGHY KPEKGGVKTK LKLGNNFMHS TEAPFPEYKT
260 270 280 290 300
QSIKKSRLIL PHYGVFKGIW DWVILVATFY VALMVPYNAA FAKADRQTKV
310 320 330 340 350
SDVIVEALFI VDILLNFRTT FVSRKGEVVS NSKQIAINYL RGWFALDLLA
360 370 380 390 400
ALPFDHLYAS DLYDGEDSHI HLVKLTRLLR LARLLQKIDR YSQHTAMILT
410 420 430 440 450
LLMFSFTLAA HWLACIWYVI AVKEYEWFPE SNIGWLQLLA ERKNASVAIL
460 470 480 490 500
TTAETYSTAL YFTFTSLTSV GFGNVSANTT AEKVFTIIMM LIGALMHAVV
510 520 530 540 550
FGNVTAIIQR MYSRRSLYES KWRDLKDFVA LHNMPKELKQ RIEDYFQTSW
560 570 580 590 600
SLSHGIDIYE TLREFPEELR GDVSMHLHRE ILQLPIFEAA SQGCLKLLSL
610 620 630 640 650
HIKTNFCAPG EYLIHKGDAL NYIYYLCNGS MEVIKDDMVV AILGKGDLVG
660 670 680 690 700
SDINVHLVAT SNGQMTATTN SAGQDVVVRS SSDIKALTYC DLKCIHMGGL
710 720 730 740 750
VEVLRLYPEY QQQFANDIQH DLTCNLREGY ENQDSDIGPS FPLPSISEDD
760 770 780 790 800
ENREEAEEGG KGEKENGGGP PSGASPLHNI SNSPLHATRS PLLGMGSPRN
810 820 830 840 850
QRLHQRGRSL ITLRETNKRH RTLNAACSLD RGSFEEPEPL EEEQSSGGKR
860 870 880 890 900
PSLERLDSQV STLHQDVAQL SAEVRNAISA LQEMTFTSNA MTSHSSLKFP
910 920 930 940 950
PARSIPNISG VAGTRSGVAV EHGLMGGVLA AAELAAMQRS SSHPPEVWGR
960 970 980 990 1000
DVQLPTSNTA SSKAPSPVEP KKTMTSRSSQ TDFYRIDFPT FERFVLANPR
1010 1020 1030 1040 1050
LVLGLLGIEP AIKNEMDLLQ QKQTLQISPL NTIDECVSPS DHNLASSKER
1060 1070 1080 1090 1100
LITSSAVPTP GRIYPPLDDE NSNDFRWTMK HSASHHSCCK STDALLSPEE
1110 1120 1130 1140 1150
QPPISILPVD ATPAPSVQEV RSSKRSIRKS TSGSNSSLSS SSSSSNSCLV
1160 1170 1180 1190 1200
SQSTGNLTTT NASVHCSNSS QSVASVATTR RASWKLQHSR SGEYRRLSEA
1210 1220 1230 1240 1250
TAEYSPPAKT PLPVAGVSYG GDEEESVELL GPRRNSRPIL LGVSQNQGQG
1260 1270 1280
QAMNFRFSAG DADKLEKGLR GLPSTRSLRD PSSK
Length:1,284
Mass (Da):141,378
Last modified:November 1, 1996 - v1
Checksum:iF09C418E19394A04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U04246 mRNA. Translation: AAA62472.1.
PIRiT13168.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U04246 mRNA. Translation: AAA62472.1.
PIRiT13168.

3D structure databases

ProteinModelPortaliQ23974.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0085981.

Proteomic databases

PaxDbiQ23974.
PRIDEiQ23974.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

FlyBaseiFBgn0011589. Elk.

Phylogenomic databases

eggNOGiKOG0498. Eukaryota.
ENOG410XPSE. LUCA.
OrthoDBiEOG091G0OXR.
PhylomeDBiQ23974.

Enzyme and pathway databases

ReactomeiR-DME-1296072. Voltage gated Potassium channels.

Miscellaneous databases

ChiTaRSielk. fly.

Gene expression databases

BgeeiFBgn0011589.
ExpressionAtlasiQ23974. differential.

Family and domain databases

Gene3Di2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR005821. Ion_trans_dom.
IPR003938. K_chnl_volt-dep_EAG/ELK/ERG.
IPR003950. K_chnl_volt-dep_ELK.
IPR001610. PAC.
IPR000014. PAS.
IPR000700. PAS-assoc_C.
IPR014710. RmlC-like_jellyroll.
[Graphical view]
PfamiPF00520. Ion_trans. 1 hit.
PF13426. PAS_9. 1 hit.
[Graphical view]
PRINTSiPR01463. EAGCHANLFMLY.
PR01465. ELKCHANNEL.
SMARTiSM00100. cNMP. 1 hit.
SM00086. PAC. 1 hit.
[Graphical view]
SUPFAMiSSF51206. SSF51206. 1 hit.
SSF55785. SSF55785. 1 hit.
TIGRFAMsiTIGR00229. sensory_box. 1 hit.
PROSITEiPS50042. CNMP_BINDING_3. 1 hit.
PS50113. PAC. 1 hit.
PS50112. PAS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ23974_DROME
AccessioniPrimary (citable) accession number: Q23974
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.