SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q23808

- AQP_CICVR

UniProt

Q23808 - AQP_CICVR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Aquaporin AQPcic

Gene
AQP, CIC
Organism
Cicadella viridis (Green leafhopper)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Forms a water-specific channel. May be involved in the transfer of excess sap dietary water from the initial midgut to the terminal midgut and the proximal part of the malpighian tubules.

GO - Molecular functioni

  1. transporter activity Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Aquaporin AQPcic
Gene namesi
Name:AQP
Synonyms:CIC
OrganismiCicadella viridis (Green leafhopper)
Taxonomic identifieri36150 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraHemipteraEuhemipteraMembracoideaCicadellidaeCicadellinaeCicadelliniCicadella

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2929Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei30 – 5021Helical; Name=1; Reviewed predictionAdd
BLAST
Topological domaini51 – 6010Extracellular Reviewed prediction
Transmembranei61 – 8121Helical; Name=2; Reviewed predictionAdd
BLAST
Topological domaini82 – 10322Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei104 – 12421Helical; Name=3; Reviewed predictionAdd
BLAST
Topological domaini125 – 14117Extracellular Reviewed predictionAdd
BLAST
Transmembranei142 – 16221Helical; Name=4; Reviewed predictionAdd
BLAST
Topological domaini163 – 17210Cytoplasmic Reviewed prediction
Transmembranei173 – 19321Helical; Name=5; Reviewed predictionAdd
BLAST
Topological domaini194 – 21522Extracellular Reviewed predictionAdd
BLAST
Transmembranei216 – 23621Helical; Name=6; Reviewed predictionAdd
BLAST
Topological domaini237 – 25519Cytoplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 255255Aquaporin AQPcicPRO_0000063975Add
BLAST

Expressioni

Tissue specificityi

Filter chamber epithelium in the digestive tract. Absent from midgut.

Interactioni

Subunit structurei

Homotetramer.

Structurei

3D structure databases

ProteinModelPortaliQ23808.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi85 – 873NPA 1
Motifi201 – 2033NPA 2

Domaini

Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR000425. MIP.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
TIGRFAMsiTIGR00861. MIP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q23808-1 [UniParc]FASTAAdd to Basket

« Hide

MAADKSVDNT KKIIGIDDIT DTKTIWRCLA AELIGTLLLV LIGTGSCTGV    50
QISEGDVVVR IALTFGFIIA TMVQCIGHVS GCHINPAVTC GLLVTGHISI 100
LKAIFYIIVQ CVGAIAGSAI LKVITPAEFR GTLCMTSLAP GVTPPMGFLV 150
EACITFVLIL LVQSVCDDRR KNLGNAAPVA VGLAITCCHL AAIKYTGSSM 200
NPARSFGPAV NGDDNWANHW VYWAGPIVGG VVAGITYRAL FRARKPEEEA 250
SSYDF 255
Length:255
Mass (Da):26,885
Last modified:November 1, 1996 - v1
Checksum:i66093CF3D1253B1D
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti120 – 14627ILKVI…VTPPM → PQGNNPCRVQGHSLYDESRP RCDPAH in CAA54921. 1 PublicationAdd
BLAST
Sequence conflicti165 – 17410VCDDRRKNLG → LRRPPQEPA in CAA54921. 1 Publication
Sequence conflicti180 – 1801A → R in CAA54921. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X97159 mRNA. Translation: CAA65799.1.
X77957 mRNA. Translation: CAA54921.1.

Cross-referencesi

Web resourcesi

Protein Spotlight

Liquid states - Issue 36 of July 2003

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X97159 mRNA. Translation: CAA65799.1 .
X77957 mRNA. Translation: CAA54921.1 .

3D structure databases

ProteinModelPortali Q23808.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.20.1080.10. 1 hit.
InterProi IPR023271. Aquaporin-like.
IPR000425. MIP.
[Graphical view ]
PANTHERi PTHR19139. PTHR19139. 1 hit.
Pfami PF00230. MIP. 1 hit.
[Graphical view ]
PRINTSi PR00783. MINTRINSICP.
SUPFAMi SSF81338. SSF81338. 1 hit.
TIGRFAMsi TIGR00861. MIP. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning and characterization of an insect aquaporin. Functional comparison with aquaporin 1."
    Le Caherec F., Deschamps S., Delamarche C., Pellerin I., Bonnec G., Guillam M.-T., Thomas D., Gouranton J., Hubert J.-F.
    Eur. J. Biochem. 241:707-715(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 245-255.
    Tissue: Filter chamber.
  2. Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 85-205.
    Tissue: Filter chamber.

Entry informationi

Entry nameiAQP_CICVR
AccessioniPrimary (citable) accession number: Q23808
Secondary accession number(s): Q23816
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi