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Protein

Glutamate dehydrogenase

Gene

gdh-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-CEL-2151201. Transcriptional activation of mitochondrial biogenesis.
R-CEL-70614. Amino acid synthesis and interconversion (transamination).

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate dehydrogenaseUniRule annotation
Gene namesi
Name:gdh-1Imported
ORF Names:CELE_ZK829.4Imported, ZK829.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiZK829.4; CE06652; WBGene00014095; gdh-1.

PTM / Processingi

Proteomic databases

EPDiQ23621.
PaxDbiQ23621.
PeptideAtlasiQ23621.
PRIDEiQ23621.

Expressioni

Gene expression databases

BgeeiWBGene00014095.

Interactioni

Protein-protein interaction databases

STRINGi6239.ZK829.4.1.

Structurei

3D structure databases

ProteinModelPortaliQ23621.
SMRiQ23621.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini243 – 532ELFV_dehydrogInterPro annotationAdd BLAST290

Sequence similaritiesi

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2250. Eukaryota.
COG0334. LUCA.
GeneTreeiENSGT00390000000854.
HOGENOMiHOG000243801.
InParanoidiQ23621.
KOiK00261.
OMAiPCFAAFP.
OrthoDBiEOG091G0KMT.
PhylomeDBiQ23621.

Family and domain databases

CDDicd01076. NAD_bind_1_Glu_DH. 1 hit.
InterProiView protein in InterPro
IPR006095. Glu/Leu/Phe/Val_DH.
IPR033524. Glu/Leu/Phe/Val_DH_AS.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
IPR033922. NAD_bind_Glu_DH.
PfamiView protein in Pfam
PF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
PIRSFiPIRSF000185. Glu_DH. 1 hit.
PRINTSiPR00082. GLFDHDRGNASE.
SMARTiView protein in SMART
SM00839. ELFV_dehydrog. 1 hit.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiView protein in PROSITE
PS00074. GLFV_DEHYDROGENASE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q23621-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSTLSRGAR SVAVRSYSAA TLDAHSQVLD EQKPMEEQVN PSFYKMVDFY
60 70 80 90 100
FNKGAEVIAP KLAEELKSNS LSQKDKKNLV SGILGAIKPV NKVLYITFPI
110 120 130 140 150
RRDNGEFEVI EAWRAQHSEH RTPTKGGIRY SLDVCEDEVK ALSALMTYKC
160 170 180 190 200
AVVDVPFGGA KGGVKIDPKQ YTDYEIEKIT RRIAIEFAKK GFLGPGVDVP
210 220 230 240 250
APDMGTGERE MGWIADTYAQ TIGHLDRDAS ACITGKPIVS GGIHGRVSAT
260 270 280 290 300
GRGVWKGLEV FTNDADYMKM VGLDTGLAGK TAIIQGFGNV GLHTHRYLHR
310 320 330 340 350
AGSKVIGIQE YDCAVYNPDG IHPKELEDWK DANGTIKNFP GAKNFDPFTE
360 370 380 390 400
LMYEKCDIFV PAACEKSIHK ENASRIQAKI IAEAANGPTT PAADRILLAR
410 420 430 440 450
GDCLIIPDMY VNSGGVTVSY FEWLKNLNHV SYGRLTFKYD EEANKMLLAS
460 470 480 490 500
VQESLSKAVG KDCPVEPNAA FAAKIAGASE KDIVHSGLEY TMQRSGEAII
510 520 530
RTAHKYNLGL DIRTAAYANS IEKVYNTYRT AGFTFT
Length:536
Mass (Da):58,795
Last modified:November 1, 1996 - v1
Checksum:i6FDCD3CB0800D0A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA98074.1.
PIRiT28022.
RefSeqiNP_502267.1. NM_069866.4.
UniGeneiCel.17808.

Genome annotation databases

EnsemblMetazoaiZK829.4.1; ZK829.4.1; WBGene00014095.
ZK829.4.2; ZK829.4.2; WBGene00014095.
GeneIDi178130.
KEGGicel:CELE_ZK829.4.
UCSCiZK829.4.1. c. elegans.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ23621_CAEEL
AccessioniPrimary (citable) accession number: Q23621
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 7, 2017
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported