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Protein
Submitted name:

Bromodomain Adjacent to Zinc finger domain, 2A/2B, homolog

Gene

baz-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Bromodomain Adjacent to Zinc finger domain, 2A/2B, homologImported
Gene namesi
Name:baz-2Imported
Synonyms:flt-1Imported
ORF Names:CELE_ZK783.4Imported, ZK783.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiZK783.4; CE47168; WBGene00001470; baz-2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiQ23590.
PaxDbiQ23590.
PRIDEiQ23590.

Interactioni

Protein-protein interaction databases

STRINGi6239.ZK783.4.

Structurei

3D structure databases

ProteinModelPortaliQ23590.
SMRiQ23590. Positions 317-405, 1103-1146, 1161-1202, 1281-1374.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini323 – 39573MBD (methyl-CpG-binding)InterPro annotationAdd
BLAST
Domaini524 – 58865DDTInterPro annotationAdd
BLAST
Domaini1100 – 114950PHD-typeInterPro annotationAdd
BLAST
Domaini1290 – 136071BromoInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili90 – 12435Sequence analysisAdd
BLAST
Coiled coili234 – 27441Sequence analysisAdd
BLAST

Keywords - Domaini

BromodomainSAAS annotation, Coiled coilSequence analysis, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG1245. Eukaryota.
COG5076. LUCA.
GeneTreeiENSGT00760000119099.
HOGENOMiHOG000015886.
InParanoidiQ23590.
OMAiELMFANC.
OrthoDBiEOG78M019.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
3.30.40.10. 2 hits.
3.30.890.10. 1 hit.
InterProiIPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR018501. DDT_dom.
IPR016177. DNA-bd_dom.
IPR001739. Methyl_CpG_DNA-bd.
IPR028942. WHIM1_dom.
IPR028941. WHIM2_dom.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00439. Bromodomain. 1 hit.
PF01429. MBD. 1 hit.
PF00628. PHD. 1 hit.
PF15612. WHIM1. 1 hit.
PF15613. WSD. 1 hit.
[Graphical view]
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 1 hit.
SM00571. DDT. 1 hit.
SM00391. MBD. 1 hit.
SM00249. PHD. 2 hits.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
SSF54171. SSF54171. 1 hit.
SSF57903. SSF57903. 2 hits.
PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS50827. DDT. 1 hit.
PS50982. MBD. 1 hit.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q23590-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDNSSNQFL LLLAAAQQQQ QQQLLQQQLA KIQKATASSP SKSTNGTSAS
60 70 80 90 100
TSAVPSTSGT SSSQNEAAQL QNLAKMQQIQ QLAQFGALMA AQKKQQEKAA
110 120 130 140 150
ADKAKEKEKE KQKAAAAAAA AAAKASASTS SASAIPGLSP EMLAAWQQAI
160 170 180 190 200
QMQALQQMMM TPQKSQMEEA IKKMMDMAKK KPAGVASTSS ASTSSSTPST
210 220 230 240 250
SSASITSSNN NAANNAASNM MNNVMWQLVA AQMQQKQQQQ QKDTQKKADQ
260 270 280 290 300
AKKAKELAKQ QQKEQDVKNK QQEEILKFLM AQHQLNHQKK HEKKQADAAA
310 320 330 340 350
LAAKVLAAHR AALESDSPEE GKKTNEAMLR LPLQLGWRRQ TCVRSIASAG
360 370 380 390 400
VKGDVSYFAP CGKKLSTYSE VVRYLTKNSI HYITRDNFLF NTKLVIGEFI
410 420 430 440 450
VPKQTEADET QQEREFAMFT EDDINKELTR LNVLKFVPKI QASTSNGVHE
460 470 480 490 500
DDIKMSKIEE PDEPLDPSEL NDEFTEELVH SQIMSNGVDE CKIREREADD
510 520 530 540 550
LLVNINDVRH LPDFSRIGNQ CLSSQGFADA LMVHEFVQNF GHVLGIDLEI
560 570 580 590 600
APKLESLCAG LDGDANHAEQ TLQLTRQLLR LALEFPGMGN EKRFGQGGGE
610 620 630 640 650
MGLDRENFSE VMRLFLIDKG KRGEELSQPL LTCNFLSISP EQKASILAFL
660 670 680 690 700
CDELVCSRNV VTEIDKNLDE ISRLKGEKWM REGKARALRS ARSKKKNDEK
710 720 730 740 750
VVVVKEEQNH ESDSEPPTRP DTPKKATVAP PTVVSVSPVS AAQQQQRKFT
760 770 780 790 800
PGLGQCEVLT EQEESMSLQQ MDSLIGDLHQ EAQNINQKIH DTGLKIRSFP
810 820 830 840 850
FGTDRFHRNY WMLAHTDKVI IESLATTSVN NPACNANEYA SKDPPTLEQR
860 870 880 890 900
VPGACETIDL DVIACVEDLV DDVVLLRAKA DKKTRKRYRR IENHMKRGWW
910 920 930 940 950
TMQNRDCVES LRSCMLSRGI RERALHRLLT KPWFLNELKF GTITIEPVGE
960 970 980 990 1000
KSDLELVRRQ GWTRLNTAID KLQCHLKMSD VSKPLPSITP FETQKPIVVP
1010 1020 1030 1040 1050
PTMALAQIVK DDMAWKVIDE EVDGQELDET IIRQKIIETA DMVQPKFWRP
1060 1070 1080 1090 1100
KFQKLEDQDT CQLFEDWKSY VSTEAQTTSQ LMVALQTLEG MIMWERSSRE
1110 1120 1130 1140 1150
ALCQICKSMD GDEMLVCDGC ESGCHMECFR PRMTKVPEGD WFCQRCREEK
1160 1170 1180 1190 1200
SGRPMCMFCS RETGNLHQCQ RCAYHVHQEC SQDGPKEAIN PETFICGHCQ
1210 1220 1230 1240 1250
EMKQMRFVKR LILRSESEER ELEDDNHAEN GENTKNGHMN GMNGAIAIGV
1260 1270 1280 1290 1300
HNQQNGVKGN LKRKLEVPSI GGLPKNMNKE LCQLMLDELV VQANALPFLE
1310 1320 1330 1340 1350
PVNPKLVPGY KMIISKPMDL KTIRQKNEKL IYETPEDFAE DIELMFANCR
1360 1370 1380 1390
QFNIDHSEIG RAGISLHKFF QKRWKQLKYN FTKRLRRLHR
Length:1,390
Mass (Da):156,593
Last modified:May 16, 2012 - v4
Checksum:i5D05420388A61B3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD65251.2.
RefSeqiNP_498673.3. NM_066272.4.
UniGeneiCel.5454.

Genome annotation databases

EnsemblMetazoaiZK783.4; ZK783.4; WBGene00001470.
GeneIDi176078.
KEGGicel:CELE_ZK783.4.
UCSCiZK783.4. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD65251.2.
RefSeqiNP_498673.3. NM_066272.4.
UniGeneiCel.5454.

3D structure databases

ProteinModelPortaliQ23590.
SMRiQ23590. Positions 317-405, 1103-1146, 1161-1202, 1281-1374.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.ZK783.4.

Proteomic databases

EPDiQ23590.
PaxDbiQ23590.
PRIDEiQ23590.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiZK783.4; ZK783.4; WBGene00001470.
GeneIDi176078.
KEGGicel:CELE_ZK783.4.
UCSCiZK783.4. c. elegans.

Organism-specific databases

CTDi176078.
WormBaseiZK783.4; CE47168; WBGene00001470; baz-2.

Phylogenomic databases

eggNOGiKOG1245. Eukaryota.
COG5076. LUCA.
GeneTreeiENSGT00760000119099.
HOGENOMiHOG000015886.
InParanoidiQ23590.
OMAiELMFANC.
OrthoDBiEOG78M019.

Miscellaneous databases

NextBioi891018.

Family and domain databases

Gene3Di1.20.920.10. 1 hit.
3.30.40.10. 2 hits.
3.30.890.10. 1 hit.
InterProiIPR001487. Bromodomain.
IPR018359. Bromodomain_CS.
IPR018501. DDT_dom.
IPR016177. DNA-bd_dom.
IPR001739. Methyl_CpG_DNA-bd.
IPR028942. WHIM1_dom.
IPR028941. WHIM2_dom.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF00439. Bromodomain. 1 hit.
PF01429. MBD. 1 hit.
PF00628. PHD. 1 hit.
PF15612. WHIM1. 1 hit.
PF15613. WSD. 1 hit.
[Graphical view]
PRINTSiPR00503. BROMODOMAIN.
SMARTiSM00297. BROMO. 1 hit.
SM00571. DDT. 1 hit.
SM00391. MBD. 1 hit.
SM00249. PHD. 2 hits.
[Graphical view]
SUPFAMiSSF47370. SSF47370. 1 hit.
SSF54171. SSF54171. 1 hit.
SSF57903. SSF57903. 2 hits.
PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
PS50014. BROMODOMAIN_2. 1 hit.
PS50827. DDT. 1 hit.
PS50982. MBD. 1 hit.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ23590_CAEEL
AccessioniPrimary (citable) accession number: Q23590
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: May 16, 2012
Last modified: May 11, 2016
This is version 127 of the entry and version 4 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.