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Protein
Submitted name:

Cytochrome P450 family monooxygenase

Gene

TTHERM_00101290

Organism
Tetrahymena thermophila (strain SB210)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. monooxygenase activity Source: UniProtKB-KW
  4. oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotationImported, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 family monooxygenaseImported
Gene namesi
ORF Names:TTHERM_00101290Imported
OrganismiTetrahymena thermophila (strain SB210)Imported
Taxonomic identifieri312017 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena
ProteomesiUP000009168 Componenti: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliQ234S0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

InParanoidiQ234S0.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.

Sequencei

Sequence statusi: Complete.

Q234S0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGYIAIALV LLFVYRFIIK NLMIYFTYKS KFGDKVVFMF YPLLGNFGIS
60 70 80 90 100
RKSFRQYGDS LHILKTIQRT KPDVKAVMVF NGFIIQIIII DTQLQKVFLQ
110 120 130 140 150
NTKPYYKVEG PFGARDAFGQ GLVVAEEKVW TRQRNFLSNS FHFNALKNRV
160 170 180 190 200
PIIKEITKEF LSTLPSDGKT PITIIEELQN ITSEVVIQTF FGENLKGMTV
210 220 230 240 250
NGLQPSVEIS KIIGDGFSYK ANSFAYFLKL MVFGQEKASR VLNTTFEKNF
260 270 280 290 300
LKRVENYNQF IEGIVDKRLS ELEKLTDTSK VDENFLNLYL LEYIKQQKAL
310 320 330 340 350
KENPKIYADY EIIPKREIVH QFTTFFFAGM DTTANQTGIC LWVLAQHPEL
360 370 380 390 400
QQKIRAEIDS VIQTFDDLKH EDLNKLEYFN AFFKESLRVY PTAPQVIPRV
410 420 430 440 450
SARDHMVDDF PIPKGAFVSN LTIQYNEQKF PLLCKDIDTF NPDRFLDKNI
460 470 480 490 500
IQDHFSFIPY SAGPRNCIGQ HLALIEAKIM IAYILKNYVV LPNEEHQKVR
510 520
FNHLFLYTSY ERDIIKLKKL TA
Length:522
Mass (Da):60,685
Last modified:April 17, 2006 - v1
Checksum:i1E4C5AB7CADB119A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG662767 Genomic DNA. Translation: EAR91933.1.
RefSeqiXP_001012178.1. XM_001012178.2.
UniGeneiTth.2998.

Genome annotation databases

EnsemblProtistsiEAR91933; EAR91933; TTHERM_00101290.
GeneIDi7841193.
KEGGitet:TTHERM_00101290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG662767 Genomic DNA. Translation: EAR91933.1.
RefSeqiXP_001012178.1. XM_001012178.2.
UniGeneiTth.2998.

3D structure databases

ProteinModelPortaliQ234S0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAR91933; EAR91933; TTHERM_00101290.
GeneIDi7841193.
KEGGitet:TTHERM_00101290.

Phylogenomic databases

InParanoidiQ234S0.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote."
    Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R., Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L., Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M., Carlton J.M.
    , Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L., Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y., Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z., Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A., Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A., Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A., Hamilton E.P., Orias E.
    PLoS Biol. 4:1620-1642(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SB210Imported.

Entry informationi

Entry nameiQ234S0_TETTS
AccessioniPrimary (citable) accession number: Q234S0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 17, 2006
Last sequence update: April 17, 2006
Last modified: January 6, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.