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Protein
Submitted name:

Elongation Factor TU family

Gene

eftu-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factorImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-CEL-72163. mRNA Splicing - Major Pathway.
R-CEL-72165. mRNA Splicing - Minor Pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
Elongation Factor TU familyImported
Gene namesi
Name:eftu-2Imported
ORF Names:CELE_ZK328.2Imported, ZK328.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiZK328.2; CE05066; WBGene00001166; eftu-2.

PTM / Processingi

Proteomic databases

EPDiQ23463.
PaxDbiQ23463.
PRIDEiQ23463.

Expressioni

Gene expression databases

ExpressionAtlasiQ23463. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ23463. 8 interactions.
STRINGi6239.ZK328.2.

Structurei

3D structure databases

ProteinModelPortaliQ23463.
SMRiQ23463. Positions 60-961.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini130 – 413284Tr-type G (guanine nucleotide-binding)InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0469. Eukaryota.
COG0480. LUCA.
GeneTreeiENSGT00840000129841.
HOGENOMiHOG000231589.
InParanoidiQ23463.
KOiK12852.
OMAiPTDTSIK.
PhylomeDBiQ23463.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
3.30.70.240. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR009022. EFG_III-V.
IPR000640. EFG_V.
IPR031950. EFTUD2_N.
IPR027417. P-loop_NTPase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR005517. Transl_elong_EFG/EF2_IV.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PfamiPF00679. EFG_C. 1 hit.
PF03764. EFG_IV. 1 hit.
PF16004. EFTUD2. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SMARTiSM00838. EFG_C. 1 hit.
SM00889. EFG_IV. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54211. SSF54211. 1 hit.
SSF54980. SSF54980. 2 hits.
PROSITEiPS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q23463-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSDLYDEFG NYIGPELDSD DDAGDIDDNG DDEDRSDVDE DDEPDRMEED
60 70 80 90 100
DAEEIPQNQV VLHEDKKYYA TALEVYGEGV ETLVQEEDAQ PLTEPIVKPV
110 120 130 140 150
SKKKFQAAER FLPETVYKKE YLADLMDCPH IMRNVAIAGH LHHGKTTFLD
160 170 180 190 200
CLMEQTHPEF YRAEDADARF TDILFIEKQR GCSIKSQPVS IVAQDSRSKS
210 220 230 240 250
YLLNIIDTPG HVNFSDEMTA SYRLADGVVV MVDAHEGVMM NTERAIRHAI
260 270 280 290 300
QERLAVTLCI SKIDRLLLEL KLPPADAYFK LRLIIDQVNN ILSTFAEEDV
310 320 330 340 350
PVLSPLNGNV IFSSGRYNVC FSLLSFSNIY AKQHGDSFNS KEFARRLWGD
360 370 380 390 400
IYFEKKTRKF VKKSPSHDAP RTFVQFILEP MYKIFSQVVG DVDTCLPDVM
410 420 430 440 450
AELGIRLSKE EQKMNVRPLI ALICKRFFGD FSAFVDLVVQ NIKSPLENAK
460 470 480 490 500
TKIEQTYLGP ADSQLAQEMQ KCNAEGPLMV HTTKNYPVDD ATQFHVFGRV
510 520 530 540 550
MSGTLEANTD VRVLGENYSI QDEEDCRRMT VGRLFVRVAS YQIEVSRVPA
560 570 580 590 600
GCWVLIEGID QPIVKTATIA ELGYEEDVYI FRPLKFNTRS CVKLAVEPIN
610 620 630 640 650
PSELPKMLDG LRKVNKSYPL LTTRVEESGE HVLLGTGEFY MDCVMHDMRK
660 670 680 690 700
VFSEIDIKVA DPVVTFNETV IETSTLKCFA ETPNKKNKIT MMAEPLEKQL
710 720 730 740 750
DEDIENEVVQ IGWNRRRLGE FFQTKYNWDL LAARSIWAFG PDTTGPNILL
760 770 780 790 800
DDTLPSEVDK HLLSTVRESL VQGFQWATRE GPLCEEPIRQ VKFKLLDAAI
810 820 830 840 850
ATEPLYRGGG QMIPTARRCA YSAFLMATPR LMEPYYTVEV VAPADCVAAV
860 870 880 890 900
YTVLAKRRGH VTTDAPMPGS PMYTISAYIP VMDSFGFETD LRIHTQGQAF
910 920 930 940 950
CMSAFHHWQL VPGDPLDKSI VIKTLDVQPT PHLAREFMIK TRRRKGLSED
960 970
VSVNKFFDDP MLLELAKQQD YTGF
Length:974
Mass (Da):110,485
Last modified:November 1, 1996 - v1
Checksum:i44C4A5FDA61F013C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD70949.1.
PIRiT29007.
RefSeqiNP_498308.1. NM_065907.5.
UniGeneiCel.8122.

Genome annotation databases

EnsemblMetazoaiZK328.2; ZK328.2; WBGene00001166.
GeneIDi175851.
KEGGicel:CELE_ZK328.2.
UCSCiZK328.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD70949.1.
PIRiT29007.
RefSeqiNP_498308.1. NM_065907.5.
UniGeneiCel.8122.

3D structure databases

ProteinModelPortaliQ23463.
SMRiQ23463. Positions 60-961.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ23463. 8 interactions.
STRINGi6239.ZK328.2.

Proteomic databases

EPDiQ23463.
PaxDbiQ23463.
PRIDEiQ23463.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiZK328.2; ZK328.2; WBGene00001166.
GeneIDi175851.
KEGGicel:CELE_ZK328.2.
UCSCiZK328.2. c. elegans.

Organism-specific databases

CTDi175851.
WormBaseiZK328.2; CE05066; WBGene00001166; eftu-2.

Phylogenomic databases

eggNOGiKOG0469. Eukaryota.
COG0480. LUCA.
GeneTreeiENSGT00840000129841.
HOGENOMiHOG000231589.
InParanoidiQ23463.
KOiK12852.
OMAiPTDTSIK.
PhylomeDBiQ23463.

Enzyme and pathway databases

ReactomeiR-CEL-72163. mRNA Splicing - Major Pathway.
R-CEL-72165. mRNA Splicing - Minor Pathway.

Miscellaneous databases

NextBioi889966.

Gene expression databases

ExpressionAtlasiQ23463. baseline and differential.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
3.30.70.240. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR009022. EFG_III-V.
IPR000640. EFG_V.
IPR031950. EFTUD2_N.
IPR027417. P-loop_NTPase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR005517. Transl_elong_EFG/EF2_IV.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PfamiPF00679. EFG_C. 1 hit.
PF03764. EFG_IV. 1 hit.
PF16004. EFTUD2. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SMARTiSM00838. EFG_C. 1 hit.
SM00889. EFG_IV. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF54211. SSF54211. 1 hit.
SSF54980. SSF54980. 2 hits.
PROSITEiPS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ23463_CAEEL
AccessioniPrimary (citable) accession number: Q23463
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 130 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.