Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Histone H2A

Gene

htas-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding

Enzyme and pathway databases

ReactomeiR-CEL-2299718. Condensation of Prophase Chromosomes.
R-CEL-2559580. Oxidative Stress Induced Senescence.
R-CEL-5578749. Transcriptional regulation by small RNAs.

Names & Taxonomyi

Protein namesi
Recommended name:
Histone H2AUniRule annotation
Gene namesi
Name:htas-1Imported
ORF Names:CELE_ZK1251.1Imported, ZK1251.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiZK1251.1; CE03848; WBGene00014240; htas-1.

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Chromosome, Nucleosome coreUniRule annotation, NucleusUniRule annotation

PTM / Processingi

Proteomic databases

EPDiQ23429.
PaxDbiQ23429.
PeptideAtlasiQ23429.

Expressioni

Gene expression databases

BgeeiWBGene00014240.

Interactioni

Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.UniRule annotation

Protein-protein interaction databases

STRINGi6239.ZK1251.1.

Structurei

3D structure databases

ProteinModelPortaliQ23429.
SMRiQ23429.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 103HistoneInterPro annotationAdd BLAST90
Domaini109 – 137Histone_H2A_CInterPro annotationAdd BLAST29

Sequence similaritiesi

Belongs to the histone H2A family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1756. Eukaryota.
COG5262. LUCA.
GeneTreeiENSGT00860000133717.
HOGENOMiHOG000234652.
InParanoidiQ23429.
KOiK11251.
OMAiLHEGANG.
OrthoDBiEOG091G0XGD.
PhylomeDBiQ23429.

Family and domain databases

Gene3Di1.10.20.10. 1 hit.
InterProiView protein in InterPro
IPR009072. Histone-fold.
IPR002119. Histone_H2A.
IPR007125. Histone_H2A/H2B/H3.
IPR032454. Histone_H2A_C.
PfamiView protein in Pfam
PF00125. Histone. 1 hit.
PF16211. Histone_H2A_C. 1 hit.
PRINTSiPR00620. HISTONEH2A.
SMARTiView protein in SMART
SM00414. H2A. 1 hit.
SUPFAMiSSF47113. SSF47113. 1 hit.

Sequencei

Sequence statusi: Complete.

Q23429-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARLKQRPNR ILNTSTKTSS AKKKKKRISR STRSGLTFPV GRIHRKLRET
60 70 80 90 100
TRGKQRISAG ASVFMAATLE YLTTELMEMS AIAANESKKS RVTPRHLHLA
110 120 130 140
IYGDQETAQL LDKVTLPQGG VTPMPIHPSL LPKKKAKEDD KENNS
Length:145
Mass (Da):16,206
Last modified:November 1, 1996 - v1
Checksum:i35530C1024C1C9C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92497.1.
PIRiT27718.
RefSeqiNP_501718.1. NM_069317.1.
UniGeneiCel.28705.

Genome annotation databases

EnsemblMetazoaiZK1251.1; ZK1251.1; WBGene00014240.
GeneIDi191549.
KEGGicel:CELE_ZK1251.1.
UCSCiZK1251.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92497.1.
PIRiT27718.
RefSeqiNP_501718.1. NM_069317.1.
UniGeneiCel.28705.

3D structure databases

ProteinModelPortaliQ23429.
SMRiQ23429.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.ZK1251.1.

Proteomic databases

EPDiQ23429.
PaxDbiQ23429.
PeptideAtlasiQ23429.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiZK1251.1; ZK1251.1; WBGene00014240.
GeneIDi191549.
KEGGicel:CELE_ZK1251.1.
UCSCiZK1251.1. c. elegans.

Organism-specific databases

CTDi191549.
WormBaseiZK1251.1; CE03848; WBGene00014240; htas-1.

Phylogenomic databases

eggNOGiKOG1756. Eukaryota.
COG5262. LUCA.
GeneTreeiENSGT00860000133717.
HOGENOMiHOG000234652.
InParanoidiQ23429.
KOiK11251.
OMAiLHEGANG.
OrthoDBiEOG091G0XGD.
PhylomeDBiQ23429.

Enzyme and pathway databases

ReactomeiR-CEL-2299718. Condensation of Prophase Chromosomes.
R-CEL-2559580. Oxidative Stress Induced Senescence.
R-CEL-5578749. Transcriptional regulation by small RNAs.

Gene expression databases

BgeeiWBGene00014240.

Family and domain databases

Gene3Di1.10.20.10. 1 hit.
InterProiView protein in InterPro
IPR009072. Histone-fold.
IPR002119. Histone_H2A.
IPR007125. Histone_H2A/H2B/H3.
IPR032454. Histone_H2A_C.
PfamiView protein in Pfam
PF00125. Histone. 1 hit.
PF16211. Histone_H2A_C. 1 hit.
PRINTSiPR00620. HISTONEH2A.
SMARTiView protein in SMART
SM00414. H2A. 1 hit.
SUPFAMiSSF47113. SSF47113. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ23429_CAEEL
AccessioniPrimary (citable) accession number: Q23429
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 15, 2017
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.