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Protein

Histone H2A

Gene

htas-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Histone H2AUniRule annotation
Gene namesi
Name:htas-1Imported
ORF Names:CELE_ZK1251.1Imported, ZK1251.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiZK1251.1; CE03848; WBGene00014240; htas-1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleosome coreUniRule annotation, NucleusUniRule annotation

PTM / Processingi

Proteomic databases

EPDiQ23429.
PaxDbiQ23429.
PeptideAtlasiQ23429.

Expressioni

Gene expression databases

BgeeiWBGene00014240.

Interactioni

Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi6239.ZK1251.1.

Structurei

3D structure databases

ProteinModelPortaliQ23429.
SMRiQ23429.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 103HistoneInterPro annotationAdd BLAST91
Domaini109 – 137Histone_H2A_CInterPro annotationAdd BLAST29

Sequence similaritiesi

Belongs to the histone H2A family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1756. Eukaryota.
COG5262. LUCA.
GeneTreeiENSGT00880000137879.
HOGENOMiHOG000234652.
InParanoidiQ23429.
KOiK11251.
OMAiLHEGANG.
OrthoDBiEOG091G0XGD.
PhylomeDBiQ23429.

Family and domain databases

InterProiView protein in InterPro
IPR009072. Histone-fold.
IPR002119. Histone_H2A.
IPR007125. Histone_H2A/H2B/H3.
IPR032454. Histone_H2A_C.
PfamiView protein in Pfam
PF00125. Histone. 1 hit.
PF16211. Histone_H2A_C. 1 hit.
PRINTSiPR00620. HISTONEH2A.
SMARTiView protein in SMART
SM00414. H2A. 1 hit.
SUPFAMiSSF47113. SSF47113. 1 hit.

Sequencei

Sequence statusi: Complete.

Q23429-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARLKQRPNR ILNTSTKTSS AKKKKKRISR STRSGLTFPV GRIHRKLRET
60 70 80 90 100
TRGKQRISAG ASVFMAATLE YLTTELMEMS AIAANESKKS RVTPRHLHLA
110 120 130 140
IYGDQETAQL LDKVTLPQGG VTPMPIHPSL LPKKKAKEDD KENNS
Length:145
Mass (Da):16,206
Last modified:November 1, 1996 - v1
Checksum:i35530C1024C1C9C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92497.1.
PIRiT27718.
RefSeqiNP_501718.1. NM_069317.1.
UniGeneiCel.28705.

Genome annotation databases

EnsemblMetazoaiZK1251.1; ZK1251.1; WBGene00014240.
GeneIDi191549.
KEGGicel:CELE_ZK1251.1.
UCSCiZK1251.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ23429_CAEEL
AccessioniPrimary (citable) accession number: Q23429
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: August 30, 2017
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported