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Q23355

- Q23355_CAEEL

UniProt

Q23355 - Q23355_CAEEL

Protein
Submitted name:

Protein ACR-8

Gene

acr-8

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 119 (01 Oct 2014)
      Sequence version 3 (13 Sep 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. acetylcholine-activated cation-selective channel activity Source: InterPro

    Keywords - Molecular functioni

    Ion channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation

    Keywords - Biological processi

    Ion transport, Transport

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein ACR-8Imported
    Gene namesi
    Name:acr-8Imported
    ORF Names:CELE_ZC504.2Imported, ZC504.2Imported
    OrganismiCaenorhabditis elegansImported
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome X

    Organism-specific databases

    WormBaseiZC504.2; CE36679; WBGene00000047; acr-8.

    Subcellular locationi

    GO - Cellular componenti

    1. cell junction Source: UniProtKB-KW
    2. integral component of membrane Source: UniProtKB-KW
    3. postsynaptic membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Proteomic databases

    PaxDbiQ23355.

    Interactioni

    Protein-protein interaction databases

    IntActiQ23355. 2 interactions.
    MINTiMINT-3383737.
    STRINGi6239.ZC504.2.

    Structurei

    3D structure databases

    ProteinModelPortaliQ23355.
    SMRiQ23355. Positions 22-356, 424-477.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    eggNOGiNOG268048.
    GeneTreeiENSGT00750000117375.
    HOGENOMiHOG000006756.
    InParanoidiQ23355.
    KOiK05312.
    OMAiWVILLNS.
    OrthoDBiEOG7J183P.
    PhylomeDBiQ23355.

    Family and domain databases

    Gene3Di1.20.120.370. 2 hits.
    2.70.170.10. 1 hit.
    InterProiIPR027361. Acetylcholine_rcpt_TM.
    IPR006202. Neur_chan_lig-bd.
    IPR006201. Neur_channel.
    IPR006029. Neurotrans-gated_channel_TM.
    IPR018000. Neurotransmitter_ion_chnl_CS.
    IPR002394. Nicotinic_acetylcholine_rcpt.
    [Graphical view]
    PANTHERiPTHR18945. PTHR18945. 1 hit.
    PfamiPF02931. Neur_chan_LBD. 1 hit.
    PF02932. Neur_chan_memb. 1 hit.
    [Graphical view]
    PRINTSiPR00254. NICOTINICR.
    PR00252. NRIONCHANNEL.
    SUPFAMiSSF63712. SSF63712. 1 hit.
    SSF90112. SSF90112. 1 hit.
    PROSITEiPS00236. NEUROTR_ION_CHANNEL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q23355-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNFAFLLRIF VYAGLFFYVN PNRYADQMYE DLLYYYNKNV RPIKNASESV    50
    KVKFGSSLIR IIDVDEVNQV LTTNLWLEMQ WFDYRLMWDP GRWGKIRKLH 100
    VPVDQIWIPD ILLYNNADGE PHITIMSDAI VYYNGLVVWK PPSIYKSFCS 150
    IDIEYFPYDT QTCWMKFGGW TYNGFLLDVR QLPVEEWTLV VTTRKLQVCA 200
    HASSISFFFR SLEWDLMELN SARHEKIYAG CCGQDFYIDI TFKIEIRRKT 250
    LFYTINLMIP CTMFAILTSI VFYVPPIEHK MTFSISILVT LTVFYLILID 300
    LVPPTSLVIP LIGKYLLFTM FLVSISIMLS VISLNFYRRD GSSFPMPHWM 350
    KVVFIHTLPR YICIKTAEED DGSDRGSSIS DIGPFMDSRR PSPFFITVNE 400
    RQLNGRLSEL KKKGMHPDLI RNMIQNVEFI AEYFNSLKKE DKVSEDWSYV 450
    ANVIDRIFLI IFSIMNVVGT WVILLNSPAL FDNRTPLFIN SVARPLSGDT 500
    FEHFINENFT QLAWWASTIK NSTTDVSDSD LCPIKYQ 537
    Length:537
    Mass (Da):62,755
    Last modified:September 13, 2004 - v3
    Checksum:i8F99AD84D5FE06A8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z50029 Genomic DNA. Translation: CAA90341.3.
    PIRiT27619.
    RefSeqiNP_509745.2. NM_077344.4.
    UniGeneiCel.11549.

    Genome annotation databases

    EnsemblMetazoaiZC504.2; ZC504.2; WBGene00000047.
    GeneIDi181246.
    KEGGicel:CELE_ZC504.2.
    UCSCiZC504.2. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z50029 Genomic DNA. Translation: CAA90341.3 .
    PIRi T27619.
    RefSeqi NP_509745.2. NM_077344.4.
    UniGenei Cel.11549.

    3D structure databases

    ProteinModelPortali Q23355.
    SMRi Q23355. Positions 22-356, 424-477.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q23355. 2 interactions.
    MINTi MINT-3383737.
    STRINGi 6239.ZC504.2.

    Proteomic databases

    PaxDbi Q23355.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai ZC504.2 ; ZC504.2 ; WBGene00000047 .
    GeneIDi 181246.
    KEGGi cel:CELE_ZC504.2.
    UCSCi ZC504.2. c. elegans.

    Organism-specific databases

    CTDi 181246.
    WormBasei ZC504.2 ; CE36679 ; WBGene00000047 ; acr-8.

    Phylogenomic databases

    eggNOGi NOG268048.
    GeneTreei ENSGT00750000117375.
    HOGENOMi HOG000006756.
    InParanoidi Q23355.
    KOi K05312.
    OMAi WVILLNS.
    OrthoDBi EOG7J183P.
    PhylomeDBi Q23355.

    Miscellaneous databases

    NextBioi 913080.

    Family and domain databases

    Gene3Di 1.20.120.370. 2 hits.
    2.70.170.10. 1 hit.
    InterProi IPR027361. Acetylcholine_rcpt_TM.
    IPR006202. Neur_chan_lig-bd.
    IPR006201. Neur_channel.
    IPR006029. Neurotrans-gated_channel_TM.
    IPR018000. Neurotransmitter_ion_chnl_CS.
    IPR002394. Nicotinic_acetylcholine_rcpt.
    [Graphical view ]
    PANTHERi PTHR18945. PTHR18945. 1 hit.
    Pfami PF02931. Neur_chan_LBD. 1 hit.
    PF02932. Neur_chan_memb. 1 hit.
    [Graphical view ]
    PRINTSi PR00254. NICOTINICR.
    PR00252. NRIONCHANNEL.
    SUPFAMi SSF63712. SSF63712. 1 hit.
    SSF90112. SSF90112. 1 hit.
    PROSITEi PS00236. NEUROTR_ION_CHANNEL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2Imported.

    Entry informationi

    Entry nameiQ23355_CAEEL
    AccessioniPrimary (citable) accession number: Q23355
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: September 13, 2004
    Last modified: October 1, 2014
    This is version 119 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3