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Protein
Submitted name:

Glutamyl(E) Amino-acyl tRNA Synthetase

Gene

ears-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseImported, Ligase

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamyl(E) Amino-acyl tRNA SynthetaseImported
Gene namesi
Name:ears-1Imported
ORF Names:CELE_ZC434.5Imported, ZC434.5Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiZC434.5; CE06580; WBGene00001337; ears-1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiQ23315.
PaxDbiQ23315.
PeptideAtlasiQ23315.
PRIDEiQ23315.

Expressioni

Gene expression databases

BgeeiWBGene00001337.

Interactioni

Protein-protein interaction databases

STRINGi6239.ZC434.5.1.

Structurei

3D structure databases

ProteinModelPortaliQ23315.
SMRiQ23315.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini729 – 785WHEP-TRSInterPro annotationAdd BLAST57
Domaini800 – 856WHEP-TRSInterPro annotationAdd BLAST57
Domaini874 – 930WHEP-TRSInterPro annotationAdd BLAST57
Domaini941 – 997WHEP-TRSInterPro annotationAdd BLAST57
Domaini1013 – 1069WHEP-TRSInterPro annotationAdd BLAST57
Domaini1085 – 1141WHEP-TRSInterPro annotationAdd BLAST57

Phylogenomic databases

eggNOGiKOG1147. Eukaryota.
COG0008. LUCA.
GeneTreeiENSGT00550000074815.
HOGENOMiHOG000022047.
InParanoidiQ23315.
KOiK01885.
OMAiGSDHKPG.
OrthoDBiEOG091G04TK.
PhylomeDBiQ23315.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
1.10.287.10. 6 hits.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR004526. Glu-tRNA-synth_arc/euk.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009068. S15_NS1_RNA-bd.
IPR000738. WHEP-TRS_dom.
[Graphical view]
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PF00458. WHEP-TRS. 6 hits.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SMARTiSM00991. WHEP-TRS. 6 hits.
[Graphical view]
SUPFAMiSSF47060. SSF47060. 6 hits.
SSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00463. gltX_arch. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
PS51185. WHEP_TRS_2. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q23315-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMITRELVLK ANREQPPYAS ILALAASGFS LEKSVQFSEK QQLALNLDGE
60 70 80 90 100
LLSNDVEIAR IIAQSTDAAD SLLGSSIIDF AVVDDLTNFI ADAVTKNDYS
110 120 130 140 150
LLLGKDFPTK ILDNSLTVAD FAIFSVAHNN PQLKAKFSGI IDKVLKEPTL
160 170 180 190 200
AAAHNFVGLY KSAAAPTATA STGKEKKKDE GKFVELPGAE KGKVVVRFPP
210 220 230 240 250
EASGYLHIGH AKAALLNQYY QQAFEGQLIM RFDDTNPAKE NAHFEHVIKE
260 270 280 290 300
DLSMLNIVPD RWTHSSDHFE MLLTMCEKLL KEGKAFVDDT DTETMRNERE
310 320 330 340 350
QRQDSRNRSN TPEKNLQLWE EMKKGSPKGL TCCVRMKIDM KSNNGAMRDP
360 370 380 390 400
TIYRCKPEEH VRTGLKYKVY PTYDFTCPIV DSVEGVTHAL RTTEYHDRDD
410 420 430 440 450
QYYFICDALG LRRPHIWEYA RLNMTNTVMS KRKLTWFVDE GHVEGWDDPR
460 470 480 490 500
LPTVRGVMRR GLTVEGLKQF IVAQGGSRSV VMMEWDKIWA FNKKVIDPVA
510 520 530 540 550
PRYTALDSTS PLVSIELTDS ISDDTSNVSL HPKNAEIGSK DVHKGKKLLL
560 570 580 590 600
EQVDAAALKE GEIVTFVNWG NIKIGKIEKK GAVITKISAT LQLDNTDYKK
610 620 630 640 650
TTKVTWLGDV KAEAGKTIPV VTADYDHIIS KAIIGKDEDW KQFINFDSVH
660 670 680 690 700
YTKMVGEPAI KNVKKGDIIQ IQRKGFYIVD QPYNPKSELS GVETPLLLIA
710 720 730 740 750
IPDGHTGKEA EKPPKGAPVS AAASSGGSDA LQLYNSIEQQ GGIVRDLKTK
760 770 780 790 800
DAKSQATKDA IAKLLDLKKK YKELTGSDHK PGAPPSAPAP TTPSSSESNS
810 820 830 840 850
ALNIYNLIEA QGLLVRELKG KDAKSQATKD AIAKLLELKK QYKEVSGSDH
860 870 880 890 900
KPGVPPAASV ASAPAPAPAA GSTNALDIYH QIESQGALVR ELKGKDAKSQ
910 920 930 940 950
ATKDAIAKLL ALKKQYKEVT GSDHKPGVVP VSAPAPTPLA GGADIAGQIE
960 970 980 990 1000
AQGVLVRDLK NKDSKSQETK DAIAKLLELK KNYKEVTGSD YKPGPAPAAA
1010 1020 1030 1040 1050
PAKVTVPAPS VSGGDTLSKQ IDDQALLVRE LKMKDAKSQE TKDAIAKLLQ
1060 1070 1080 1090 1100
LKKQYKDATG SDYKPAPAQL AASAAAAPAP APAFDEAALL KEIEEQGAVV
1110 1120 1130 1140
RDAKSKDPKS QDSADAINKL LALKANFKKA TGKDFPAPSN AQSKKGKKK
Length:1,149
Mass (Da):125,198
Last modified:November 1, 1996 - v1
Checksum:iCC22744C05C0A433
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAB00060.1.
PIRiT27567.
RefSeqiNP_492711.1. NM_060310.5.
UniGeneiCel.4980.

Genome annotation databases

EnsemblMetazoaiZC434.5.1; ZC434.5.1; WBGene00001337.
ZC434.5.2; ZC434.5.2; WBGene00001337.
GeneIDi172904.
KEGGicel:CELE_ZC434.5.
UCSCiZC434.5.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAB00060.1.
PIRiT27567.
RefSeqiNP_492711.1. NM_060310.5.
UniGeneiCel.4980.

3D structure databases

ProteinModelPortaliQ23315.
SMRiQ23315.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.ZC434.5.1.

Proteomic databases

EPDiQ23315.
PaxDbiQ23315.
PeptideAtlasiQ23315.
PRIDEiQ23315.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiZC434.5.1; ZC434.5.1; WBGene00001337.
ZC434.5.2; ZC434.5.2; WBGene00001337.
GeneIDi172904.
KEGGicel:CELE_ZC434.5.
UCSCiZC434.5.2. c. elegans.

Organism-specific databases

CTDi172904.
WormBaseiZC434.5; CE06580; WBGene00001337; ears-1.

Phylogenomic databases

eggNOGiKOG1147. Eukaryota.
COG0008. LUCA.
GeneTreeiENSGT00550000074815.
HOGENOMiHOG000022047.
InParanoidiQ23315.
KOiK01885.
OMAiGSDHKPG.
OrthoDBiEOG091G04TK.
PhylomeDBiQ23315.

Miscellaneous databases

PROiQ23315.

Gene expression databases

BgeeiWBGene00001337.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
1.10.287.10. 6 hits.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR004526. Glu-tRNA-synth_arc/euk.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009068. S15_NS1_RNA-bd.
IPR000738. WHEP-TRS_dom.
[Graphical view]
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PF00458. WHEP-TRS. 6 hits.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SMARTiSM00991. WHEP-TRS. 6 hits.
[Graphical view]
SUPFAMiSSF47060. SSF47060. 6 hits.
SSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00463. gltX_arch. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
PS51185. WHEP_TRS_2. 6 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ23315_CAEEL
AccessioniPrimary (citable) accession number: Q23315
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 132 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.