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Protein

alpha-1,2-Mannosidase

Gene

mans-4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Enzyme and pathway databases

ReactomeiR-CEL-901032. ER Quality Control Compartment (ERQC).

Protein family/group databases

CAZyiGH47. Glycoside Hydrolase Family 47.

Names & Taxonomyi

Protein namesi
Recommended name:
alpha-1,2-MannosidaseUniRule annotation (EC:3.2.1.-UniRule annotation)
Gene namesi
Name:mans-4Imported
ORF Names:CELE_ZC410.3Imported, ZC410.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiZC410.3a; CE03807; WBGene00013881; mans-4.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3120HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ23296.

Expressioni

Gene expression databases

BgeeiWBGene00013881.
ExpressionAtlasiQ23296. baseline.

Interactioni

Protein-protein interaction databases

IntActiQ23296. 1 interaction.
MINTiMINT-3386402.
STRINGi6239.ZC410.3a.

Structurei

3D structure databases

ProteinModelPortaliQ23296.
SMRiQ23296. Positions 80-531.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 47 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2431. Eukaryota.
ENOG410XP04. LUCA.
GeneTreeiENSGT00390000016529.
HOGENOMiHOG000181987.
InParanoidiQ23296.
KOiK01230.
OMAiEMAKNIG.
OrthoDBiEOG091G0342.
PhylomeDBiQ23296.

Family and domain databases

Gene3Di1.50.10.50. 1 hit.
InterProiIPR001382. Glyco_hydro_47.
[Graphical view]
PfamiPF01532. Glyco_hydro_47. 1 hit.
[Graphical view]
PRINTSiPR00747. GLYHDRLASE47.
SUPFAMiSSF48225. SSF48225. 1 hit.

Sequencei

Sequence statusi: Complete.

Q23296-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRIKINRKT LFILFIAYMQ LLVFLALYLN LAGPAELLNP RRQKFFGTNS
60 70 80 90 100
ANRQNSNETY GTPKATKLKR APPVFQGPTN ERQKAIVRAF QHAWSGYKKY
110 120 130 140 150
AWGHDELRPV SKRFDDSFGL GLTIIDSLDT AIIMGLEEET RDGVEWIREN
160 170 180 190 200
LNVSPARSVN VFETTIRVLG GLLSGYHLTG EEALLEKATQ LGDNLIKAFT
210 220 230 240 250
KSSSLIPKSD VNLDNGNACS PNRDLSSLAE ATTLQLEFRD LTALTGDQKY
260 270 280 290 300
EDVAFGASEH VHNVGCKKMD GLCPFYIDGK GEFKKSSITL GARADSYYEY
310 320 330 340 350
LIKQWLQTKK SIDWLRDDFI QSIAAMKKHL YRQSQPNSIW FLGEITELAQ
360 370 380 390 400
FYPKMDHLVC FLSGSLVLSH LNGLDHDNEH LEMAKNIGNV CHKMYENPTG
410 420 430 440 450
LGPEIIHFNM EDSSDMTQAD TYVKNLDAHS LLRPEAIEAW FYLYRVTKDK
460 470 480 490 500
KYQEWGWKAF ESIEKYAKVE TGGYSSIDNV LRKKIKRRDK MESFFLAETL
510 520 530
KYLYLLMADD QEILPLDRWV LNTEAHPLPI YN
Length:532
Mass (Da):60,836
Last modified:November 1, 1996 - v1
Checksum:iD7F6BB8540BA7386
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92567.1.
PIRiT27549.
RefSeqiNP_001255361.1. NM_001268432.1.
UniGeneiCel.39445.
Cel.39536.

Genome annotation databases

EnsemblMetazoaiZC410.3a; ZC410.3a; WBGene00013881.
GeneIDi177726.
KEGGicel:CELE_ZC410.3.
UCSCiZC410.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92567.1.
PIRiT27549.
RefSeqiNP_001255361.1. NM_001268432.1.
UniGeneiCel.39445.
Cel.39536.

3D structure databases

ProteinModelPortaliQ23296.
SMRiQ23296. Positions 80-531.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ23296. 1 interaction.
MINTiMINT-3386402.
STRINGi6239.ZC410.3a.

Protein family/group databases

CAZyiGH47. Glycoside Hydrolase Family 47.

Proteomic databases

PaxDbiQ23296.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiZC410.3a; ZC410.3a; WBGene00013881.
GeneIDi177726.
KEGGicel:CELE_ZC410.3.
UCSCiZC410.3. c. elegans.

Organism-specific databases

CTDi177726.
WormBaseiZC410.3a; CE03807; WBGene00013881; mans-4.

Phylogenomic databases

eggNOGiKOG2431. Eukaryota.
ENOG410XP04. LUCA.
GeneTreeiENSGT00390000016529.
HOGENOMiHOG000181987.
InParanoidiQ23296.
KOiK01230.
OMAiEMAKNIG.
OrthoDBiEOG091G0342.
PhylomeDBiQ23296.

Enzyme and pathway databases

ReactomeiR-CEL-901032. ER Quality Control Compartment (ERQC).

Gene expression databases

BgeeiWBGene00013881.
ExpressionAtlasiQ23296. baseline.

Family and domain databases

Gene3Di1.50.10.50. 1 hit.
InterProiIPR001382. Glyco_hydro_47.
[Graphical view]
PfamiPF01532. Glyco_hydro_47. 1 hit.
[Graphical view]
PRINTSiPR00747. GLYHDRLASE47.
SUPFAMiSSF48225. SSF48225. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ23296_CAEEL
AccessioniPrimary (citable) accession number: Q23296
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.