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Protein

Probable cytochrome c 2.2

Gene

cyc-2.2

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei30Heme (covalent)PROSITE-ProRule annotation1
Binding sitei33Heme (covalent)PROSITE-ProRule annotation1
Metal bindingi34Iron (heme axial ligand)PROSITE-ProRule annotation1
Metal bindingi95Iron (heme axial ligand)PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chain, Transport
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-CEL-111457 Release of apoptotic factors from the mitochondria
R-CEL-3299685 Detoxification of Reactive Oxygen Species

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cytochrome c 2.2
Gene namesi
Name:cyc-2.2
ORF Names:ZC116.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiZC116.2 ; CE06565 ; WBGene00013854 ; cyc-2.2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001082721 – 123Probable cytochrome c 2.2Add BLAST123

Post-translational modificationi

Binds 1 heme group per subunit.By similarity

Proteomic databases

EPDiQ23240
PaxDbiQ23240
PeptideAtlasiQ23240
PRIDEiQ23240

Expressioni

Gene expression databases

BgeeiWBGene00013854

Interactioni

Protein-protein interaction databases

STRINGi6239.ZC116.2

Structurei

3D structure databases

ProteinModelPortaliQ23240
SMRiQ23240
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c family.Curated

Phylogenomic databases

eggNOGiKOG3453 Eukaryota
COG3474 LUCA
GeneTreeiENSGT00390000009405
InParanoidiQ23240
KOiK08738
OMAiGLFKTRC
OrthoDBiEOG091G0UQY
PhylomeDBiQ23240

Family and domain databases

Gene3Di1.10.760.10, 1 hit
InterProiView protein in InterPro
IPR009056 Cyt_c-like_dom
IPR036909 Cyt_c-like_dom_sf
IPR002327 Cyt_c_1A/1B
PANTHERiPTHR11961 PTHR11961, 1 hit
PfamiView protein in Pfam
PF00034 Cytochrom_C, 1 hit
PRINTSiPR00604 CYTCHRMECIAB
SUPFAMiSSF46626 SSF46626, 1 hit
PROSITEiView protein in PROSITE
PS51007 CYTC, 1 hit

Sequencei

Sequence statusi: Complete.

Q23240-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKKKSDTAS GGAIPEGDNE KGKKIFKQRC EQCHVVNSLQ TKTGPTLNGV
60 70 80 90 100
IGRQSGQVAG FDYSAANKNK GVVWDRQTLF DYLADPKKYI PGTKMVFAGL
110 120
KKADERADLI KFIEVEAAKK PSA
Length:123
Mass (Da):13,362
Last modified:November 1, 1996 - v1
Checksum:i6FBC24AF847F596C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z74046 Genomic DNA Translation: CAA98555.1
PIRiT27492
RefSeqiNP_506156.1, NM_073755.3
UniGeneiCel.1420

Genome annotation databases

EnsemblMetazoaiZC116.2; ZC116.2; WBGene00013854
GeneIDi179728
KEGGicel:CELE_ZC116.2

Similar proteinsi

Entry informationi

Entry nameiCYC22_CAEEL
AccessioniPrimary (citable) accession number: Q23240
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 138 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  3. SIMILARITY comments
    Index of protein domains and families

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