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Protein

mRNA transport homolog 4

Gene

mtr-4

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi147 – 154ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicase, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
mRNA transport homolog 4
Alternative name(s):
Uncharacterized helicase W08D2.7 (EC:3.6.4.-)
Gene namesi
Name:mtr-4
ORF Names:W08D2.7
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiW08D2.7; CE06562; WBGene00012342; mtr-4.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001020971 – 1026mRNA transport homolog 4Add BLAST1026

Proteomic databases

EPDiQ23223.
PaxDbiQ23223.
PeptideAtlasiQ23223.
PRIDEiQ23223.

Expressioni

Gene expression databases

BgeeiWBGene00012342.

Interactioni

Protein-protein interaction databases

MINTiMINT-6670291.
STRINGi6239.W08D2.7.

Structurei

3D structure databases

ProteinModelPortaliQ23223.
SMRiQ23223.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini134 – 290Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST157
Domaini360 – 564Helicase C-terminalPROSITE-ProRule annotationAdd BLAST205

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi238 – 241DEIH box4

Sequence similaritiesi

Belongs to the helicase family. SKI2 subfamily.Curated

Phylogenomic databases

eggNOGiKOG0948. Eukaryota.
COG4581. LUCA.
GeneTreeiENSGT00820000127042.
HOGENOMiHOG000163047.
InParanoidiQ23223.
KOiK12598.
OMAiNMLYRGS.
OrthoDBiEOG091G01TA.
PhylomeDBiQ23223.

Family and domain databases

InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR018247. EF_Hand_1_Ca_BS.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR025696. rRNA_proc-arch_dom.
IPR016438. Ski2.
IPR012961. Ski2_C.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF08148. DSHCT. 1 hit.
PF00271. Helicase_C. 1 hit.
PF13234. rRNA_proc-arch. 1 hit.
PIRSFiPIRSF005198. Antiviral_helicase_SKI2. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM01142. DSHCT. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q23223-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADLFDEFIE PGVKNEIMDV EEAPENPMEK LDSAKKRQAR EDMTNLLANM
60 70 80 90 100
HNDVGVGNFD EATSKRARVE EEEEVEEARM ENIIVHTIRT DNENCTHEVA
110 120 130 140 150
IPPNAEFAEL RENSGTEPAK YYPFQLDAFQ KQAILCIDNN QSVLVSAHTS
160 170 180 190 200
AGKTVVATYA IAKCLREKQR VIYTSPIKAL SNQKYRELEE EFKDVGLMTG
210 220 230 240 250
DVTLNPDASC LVMTTEILRS MLYRGSEIMK EVGWVVYDEI HYMRDKERGV
260 270 280 290 300
VWEETIILMS KNIKQAFLSA TIPNARQFAQ WVASIKQQPV NVVYTDYRPT
310 320 330 340 350
PLQHWIYPVG GEGMYEVVNV KGEFREDKFR DAMSGLATAG DSAGSFNKRR
360 370 380 390 400
TGGGTQGDSN VLKIIRSVAS NDGLNCIVFS FSRKECESYA ISLKDMDFNK
410 420 430 440 450
DHEKGMVKSV YESAIAQLSP EDQKLPQILN ILPLLRRGIG VHHSGLMPIL
460 470 480 490 500
KETIEILFGE GLVKVLFATE TFSMGLNMPA RTVVFTSARK FDGSDNRYIT
510 520 530 540 550
SGEYIQMAGR AGRRGKDDRG TVILMVDSAM SADDAKQIIK GATDPLNSQF
560 570 580 590 600
RLTYNMVLNL MRVEGMAVSW IINNSFHQFQ SYAKIPEIDK KCVQVERKIA
610 620 630 640 650
SFNFPWENEM RTLVDLQDQL EATRQRIIQI QREPKYIVGF LHAGRLFKVK
660 670 680 690 700
SGDRDFKWGI LNQFKKEQNP DDRNDQIYLC DMMIAINTEG RFDPTNPATL
710 720 730 740 750
VPGFDLPKRR WIRVPMTIDR ITAISAVRLK VPADIDKPDG QMRLDGMMAA
760 770 780 790 800
ATKRFGNQIP LLDPIQDMEI KTVEMKELIA REKSLEGRLE THSMTKRDNM
810 820 830 840 850
KDLKKQFEQK QDAVKELNAL KAERKSVQST LHLEELNNRK RVLRRLGYLG
860 870 880 890 900
NDDALVLKGS VACELSASDE LILTEMLLKG IFNTLDVAQT AALLSCFVFQ
910 920 930 940 950
DKCAAPKLAT ELQTCLSELH EQARNVAKVS NECKMEVMED KYVSSFNPGL
960 970 980 990 1000
MDVVYQWVNG ATFSEIVKTT DVFEGSIIRT LRRLEEVLRE MINAAKALAN
1010 1020
KELEQKFEDA RKNLKRDIVF AASLYL
Length:1,026
Mass (Da):116,370
Last modified:November 1, 1996 - v1
Checksum:i7AC420E41222A92E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z70271 Genomic DNA. Translation: CAA94235.1.
PIRiT26282.
RefSeqiNP_501757.1. NM_069356.5.
UniGeneiCel.22060.

Genome annotation databases

EnsemblMetazoaiW08D2.7; W08D2.7; WBGene00012342.
GeneIDi177824.
KEGGicel:CELE_W08D2.7.

Similar proteinsi

Entry informationi

Entry nameiMTR4_CAEEL
AccessioniPrimary (citable) accession number: Q23223
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: June 7, 2017
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families