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Protein
Submitted name:

RAB family

Gene

rab-7

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GTPase activity Source: WormBase
  • GTP binding Source: InterPro

GO - Biological processi

  • body morphogenesis Source: WormBase
  • endosomal transport Source: WormBase
  • endosome to lysosome transport Source: GO_Central
  • oocyte growth Source: WormBase
  • phagolysosome assembly involved in apoptotic cell clearance Source: WormBase
  • phagosome-lysosome fusion Source: GO_Central
  • small GTPase mediated signal transduction Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
RAB familyImported
Gene namesi
Name:rab-7Imported
ORF Names:CELE_W03C9.3Imported, W03C9.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiW03C9.3; CE03777; WBGene00004271; rab-7.

Subcellular locationi

GO - Cellular componenti

  • late endosome Source: WormBase
  • lysosome Source: WormBase
  • organelle membrane Source: WormBase
  • phagocytic vesicle Source: WormBase
  • phagocytic vesicle membrane Source: WormBase
  • vacuolar membrane Source: GO_Central
Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiQ23146.
PaxDbiQ23146.

Expressioni

Gene expression databases

ExpressionAtlasiQ23146. baseline.

Interactioni

Protein-protein interaction databases

IntActiQ23146. 1 interaction.
STRINGi6239.W03C9.3.3.

Structurei

3D structure databases

ProteinModelPortaliQ23146.
SMRiQ23146. Positions 7-181.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0394. Eukaryota.
ENOG410XNZV. LUCA.
GeneTreeiENSGT00760000119125.
HOGENOMiHOG000233968.
InParanoidiQ23146.
KOiK07897.
OMAiQQESFAH.
PhylomeDBiQ23146.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q23146-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGTRKKALL KVIILGDSGV GKTSLMNQYV NRRFSNQYKA TIGADFLTRD
60 70 80 90 100
VNIDDRTVTL QIWDTAGQER FQSLGVAFYR GADCCVLAFD VTNAASFKSL
110 120 130 140 150
DSWRDEFLIQ ASPRDPDHFP FVLLGNKVDL ESQRAVSSKR AQSWCQTKGN
160 170 180 190 200
IPYYEVSAKE ALNVEAAFLA IARDALARES QETNDFPEFP DQIRLNPNQQ

NQQNSGCNC
Length:209
Mass (Da):23,429
Last modified:November 1, 1996 - v1
Checksum:i1797B3E7B887F255
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAA91357.1.
PIRiT26119.
RefSeqiNP_496549.1. NM_064148.5.
UniGeneiCel.16894.

Genome annotation databases

EnsemblMetazoaiW03C9.3.1; W03C9.3.1; WBGene00004271.
W03C9.3.2; W03C9.3.2; WBGene00004271.
GeneIDi174834.
KEGGicel:CELE_W03C9.3.
UCSCiW03C9.3.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAA91357.1.
PIRiT26119.
RefSeqiNP_496549.1. NM_064148.5.
UniGeneiCel.16894.

3D structure databases

ProteinModelPortaliQ23146.
SMRiQ23146. Positions 7-181.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ23146. 1 interaction.
STRINGi6239.W03C9.3.3.

Proteomic databases

EPDiQ23146.
PaxDbiQ23146.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiW03C9.3.1; W03C9.3.1; WBGene00004271.
W03C9.3.2; W03C9.3.2; WBGene00004271.
GeneIDi174834.
KEGGicel:CELE_W03C9.3.
UCSCiW03C9.3.1. c. elegans.

Organism-specific databases

CTDi174834.
WormBaseiW03C9.3; CE03777; WBGene00004271; rab-7.

Phylogenomic databases

eggNOGiKOG0394. Eukaryota.
ENOG410XNZV. LUCA.
GeneTreeiENSGT00760000119125.
HOGENOMiHOG000233968.
InParanoidiQ23146.
KOiK07897.
OMAiQQESFAH.
PhylomeDBiQ23146.

Gene expression databases

ExpressionAtlasiQ23146. baseline.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ23146_CAEEL
AccessioniPrimary (citable) accession number: Q23146
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 127 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.