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Protein
Submitted name:

RAB family

Gene

rab-7

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GTPase activity Source: WormBase
  • GTP binding Source: InterPro

GO - Biological processi

  • body morphogenesis Source: WormBase
  • endosomal transport Source: WormBase
  • oocyte growth Source: WormBase
  • phagolysosome assembly involved in apoptotic cell clearance Source: WormBase

Enzyme and pathway databases

ReactomeiR-CEL-6798695. Neutrophil degranulation.
R-CEL-8854214. TBC/RABGAPs.
R-CEL-8876198. RAB GEFs exchange GTP for GDP on RABs.

Names & Taxonomyi

Protein namesi
Submitted name:
RAB familyImported
Gene namesi
Name:rab-7Imported
ORF Names:CELE_W03C9.3Imported, W03C9.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiW03C9.3; CE03777; WBGene00004271; rab-7.

Subcellular locationi

GO - Cellular componenti

  • late endosome Source: WormBase
  • lysosome Source: WormBase
  • organelle membrane Source: WormBase
  • phagocytic vesicle Source: WormBase
  • phagocytic vesicle membrane Source: WormBase

PTM / Processingi

Proteomic databases

EPDiQ23146.
PaxDbiQ23146.

Expressioni

Gene expression databases

BgeeiWBGene00004271.
ExpressionAtlasiQ23146. baseline.

Interactioni

Protein-protein interaction databases

IntActiQ23146. 1 interactor.
STRINGi6239.W03C9.3.3.

Structurei

3D structure databases

ProteinModelPortaliQ23146.
SMRiQ23146.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0394. Eukaryota.
ENOG410XNZV. LUCA.
GeneTreeiENSGT00760000119125.
HOGENOMiHOG000233968.
InParanoidiQ23146.
KOiK07897.
OMAiLMQQFVN.
OrthoDBiEOG091G0JIV.
PhylomeDBiQ23146.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q23146-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGTRKKALL KVIILGDSGV GKTSLMNQYV NRRFSNQYKA TIGADFLTRD
60 70 80 90 100
VNIDDRTVTL QIWDTAGQER FQSLGVAFYR GADCCVLAFD VTNAASFKSL
110 120 130 140 150
DSWRDEFLIQ ASPRDPDHFP FVLLGNKVDL ESQRAVSSKR AQSWCQTKGN
160 170 180 190 200
IPYYEVSAKE ALNVEAAFLA IARDALARES QETNDFPEFP DQIRLNPNQQ

NQQNSGCNC
Length:209
Mass (Da):23,429
Last modified:November 1, 1996 - v1
Checksum:i1797B3E7B887F255
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAA91357.1.
PIRiT26119.
RefSeqiNP_496549.1. NM_064148.5.
UniGeneiCel.16894.

Genome annotation databases

EnsemblMetazoaiW03C9.3.1; W03C9.3.1; WBGene00004271.
W03C9.3.2; W03C9.3.2; WBGene00004271.
GeneIDi174834.
KEGGicel:CELE_W03C9.3.
UCSCiW03C9.3.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ23146_CAEEL
AccessioniPrimary (citable) accession number: Q23146
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: August 30, 2017
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported