Q22H00 (Q22H00_TETTS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Cu-Zn] RuleBase RU000393
EC=1.15.1.1 RuleBase RU000393

Gene names

ORF Names:

TTHERM_00655520 EMBL EAR84524.1

Organism

Tetrahymena thermophila (strain SB210) [Reference proteome]

Taxonomic identifier

312017 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Alveolata › Ciliophora › Intramacronucleata › Oligohymenophorea › Hymenostomatida › Tetrahymenina › Tetrahymenidae › Tetrahymena › Tetrahymena thermophila

Protein attributes

Sequence length	166 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity. RuleBase RU000393
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2. RuleBase RU000393
Cofactor	Binds 1 copper ion per subunit By similarity. RuleBase RU000393 Binds 1 zinc ion per subunit By similarity. RuleBase RU000393
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family. RuleBase RU000393

Ontologies

Keywords
Ligand	Copper RuleBase RU000393 Metal-binding RuleBase RU000393 Zinc RuleBase RU000393
Molecular function	Oxidoreductase RuleBase RU000393 EMBL EAR84524.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	removal of superoxide radicals Inferred from Biological aspect of Ancestor. Source: RefGenome
Molecular_function	copper ion binding Inferred from Biological aspect of Ancestor. Source: RefGenome superoxide dismutase activity Inferred from Biological aspect of Ancestor. Source: RefGenome zinc ion binding Inferred from Biological aspect of Ancestor. Source: RefGenome
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q22H00 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 742B4B90762A8AB6	FASTA	166	17,900
	10 20 30 40 50 60 MAQHAPVYAI CLLKNETNTV SAVVRLVEKF ENNKFVTHLK ATFKGLPAGL HGFHVHQYGD 70 80 90 100 110 120 LSNGCATAGP HFNPFNKQHG GPNDENRHVG DLGNVTAVDG QDTNFEFQSD LIRLSGENTI 130 140 150 160 VGRSFVIHAD EDDLGKGNFE DSKTTGHAGA RLACGIIALA APFENF

References

[1]

"Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote." Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R., Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L., Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M., Carlton J.M. , Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L., Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y., Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z., Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A., Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A., Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A., Hamilton E.P., Orias E. PLoS Biol. 4:1620-1642(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SB210.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GG662502 Genomic DNA. Translation: EAR84524.1.
RefSeq	XP_001032187.1. XM_001032187.2.
UniGene	Tth.445.
3D structure databases
ProteinModelPortal	Q22H00.
ModBase	Search...
Protein-protein interaction databases
STRING	5911.XP_001032187.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	EAR84524; EAR84524; TTHERM_00655520.
GeneID	7823633.
KEGG	tet:TTHERM_00655520.
Phylogenomic databases
KO	K04565.
ProtClustDB	CLSZ2429689.
Family and domain databases
Gene3D	2.60.40.200. 1 hit.
InterPro	IPR024134. SOD_Cu/Zn_/chaperones. IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn_dom. [Graphical view]
PANTHER	PTHR10003. PTHR10003. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
SUPFAM	SSF49329. SOD_Cu_Zn. 1 hit.
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q22H00_TETTS

Accession

Primary (citable) accession number: Q22H00

Entry history

Integrated into UniProtKB/TrEMBL:	April 18, 2006
Last sequence update:	April 18, 2006
Last modified:	April 3, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)