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Q22H00

- Q22H00_TETTS

UniProt

Q22H00 - Q22H00_TETTS

Protein

Superoxide dismutase [Cu-Zn]

Gene

TTHERM_00655520

Organism
Tetrahymena thermophila (strain SB210)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (18 Apr 2006)
      Previous versions | rss
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    Functioni

    Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

    Catalytic activityi

    2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

    Cofactori

    Binds 1 copper ion per subunit.UniRule annotation
    Binds 1 zinc ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. copper ion binding Source: RefGenome
    2. superoxide dismutase activity Source: RefGenome
    3. zinc ion binding Source: RefGenome

    GO - Biological processi

    1. removal of superoxide radicals Source: RefGenome

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Ligandi

    CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
    Gene namesi
    ORF Names:TTHERM_00655520Imported
    OrganismiTetrahymena thermophila (strain SB210)Imported
    Taxonomic identifieri312017 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena
    ProteomesiUP000009168: Unassembled WGS sequence

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: RefGenome

    Interactioni

    Protein-protein interaction databases

    STRINGi5911.XP_001032187.

    Structurei

    3D structure databases

    ProteinModelPortaliQ22H00.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

    Phylogenomic databases

    KOiK04565.

    Family and domain databases

    Gene3Di2.60.40.200. 1 hit.
    InterProiIPR018152. SOD_Cu/Zn_BS.
    IPR001424. SOD_Cu_Zn_dom.
    [Graphical view]
    PfamiPF00080. Sod_Cu. 1 hit.
    [Graphical view]
    PRINTSiPR00068. CUZNDISMTASE.
    SUPFAMiSSF49329. SSF49329. 1 hit.
    PROSITEiPS00087. SOD_CU_ZN_1. 1 hit.
    PS00332. SOD_CU_ZN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q22H00-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAQHAPVYAI CLLKNETNTV SAVVRLVEKF ENNKFVTHLK ATFKGLPAGL    50
    HGFHVHQYGD LSNGCATAGP HFNPFNKQHG GPNDENRHVG DLGNVTAVDG 100
    QDTNFEFQSD LIRLSGENTI VGRSFVIHAD EDDLGKGNFE DSKTTGHAGA 150
    RLACGIIALA APFENF 166
    Length:166
    Mass (Da):17,900
    Last modified:April 18, 2006 - v1
    Checksum:i742B4B90762A8AB6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG662502 Genomic DNA. Translation: EAR84524.1.
    RefSeqiXP_001032187.1. XM_001032187.2.
    UniGeneiTth.445.

    Genome annotation databases

    EnsemblProtistsiEAR84524; EAR84524; TTHERM_00655520.
    GeneIDi7823633.
    KEGGitet:TTHERM_00655520.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG662502 Genomic DNA. Translation: EAR84524.1 .
    RefSeqi XP_001032187.1. XM_001032187.2.
    UniGenei Tth.445.

    3D structure databases

    ProteinModelPortali Q22H00.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5911.XP_001032187.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi EAR84524 ; EAR84524 ; TTHERM_00655520 .
    GeneIDi 7823633.
    KEGGi tet:TTHERM_00655520.

    Phylogenomic databases

    KOi K04565.

    Family and domain databases

    Gene3Di 2.60.40.200. 1 hit.
    InterProi IPR018152. SOD_Cu/Zn_BS.
    IPR001424. SOD_Cu_Zn_dom.
    [Graphical view ]
    Pfami PF00080. Sod_Cu. 1 hit.
    [Graphical view ]
    PRINTSi PR00068. CUZNDISMTASE.
    SUPFAMi SSF49329. SSF49329. 1 hit.
    PROSITEi PS00087. SOD_CU_ZN_1. 1 hit.
    PS00332. SOD_CU_ZN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote."
      Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R., Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L., Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M., Carlton J.M.
      , Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L., Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y., Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z., Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A., Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A., Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A., Hamilton E.P., Orias E.
      PLoS Biol. 4:1620-1642(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SB210Imported.

    Entry informationi

    Entry nameiQ22H00_TETTS
    AccessioniPrimary (citable) accession number: Q22H00
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 18, 2006
    Last sequence update: April 18, 2006
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3