Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Superoxide dismutase [Cu-Zn]

Gene

TTHERM_00655520

Organism
Tetrahymena thermophila (strain SB210)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandCopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
ORF Names:TTHERM_00655520Imported
OrganismiTetrahymena thermophila (strain SB210)Imported
Taxonomic identifieri312017 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaHymenostomatidaTetrahymeninaTetrahymenidaeTetrahymena
Proteomesi
  • UP000009168 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi5911.EAR84524

Structurei

3D structure databases

ProteinModelPortaliQ22H00
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 157Sod_CuInterPro annotationAdd BLAST141

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Phylogenomic databases

InParanoidiQ22H00
KOiK04565
OMAiIHTFGDN

Family and domain databases

CDDicd00305 Cu-Zn_Superoxide_Dismutase, 1 hit
Gene3Di2.60.40.200, 1 hit
InterProiView protein in InterPro
IPR036423 SOD-like_Cu/Zn_dom_sf
IPR024134 SOD_Cu/Zn_/chaperone
IPR018152 SOD_Cu/Zn_BS
IPR001424 SOD_Cu_Zn_dom
PANTHERiPTHR10003 PTHR10003, 1 hit
PfamiView protein in Pfam
PF00080 Sod_Cu, 1 hit
PRINTSiPR00068 CUZNDISMTASE
SUPFAMiSSF49329 SSF49329, 1 hit
PROSITEiView protein in PROSITE
PS00087 SOD_CU_ZN_1, 1 hit
PS00332 SOD_CU_ZN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q22H00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQHAPVYAI CLLKNETNTV SAVVRLVEKF ENNKFVTHLK ATFKGLPAGL
60 70 80 90 100
HGFHVHQYGD LSNGCATAGP HFNPFNKQHG GPNDENRHVG DLGNVTAVDG
110 120 130 140 150
QDTNFEFQSD LIRLSGENTI VGRSFVIHAD EDDLGKGNFE DSKTTGHAGA
160
RLACGIIALA APFENF
Length:166
Mass (Da):17,900
Last modified:April 18, 2006 - v1
Checksum:i742B4B90762A8AB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG662502 Genomic DNA Translation: EAR84524.1
RefSeqiXP_001032187.1, XM_001032187.3

Genome annotation databases

EnsemblProtistsiEAR84524; EAR84524; TTHERM_00655520
GeneIDi7823633
KEGGitet:TTHERM_00655520

Similar proteinsi

Entry informationi

Entry nameiQ22H00_TETTS
AccessioniPrimary (citable) accession number: Q22H00
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: March 28, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health