Q22979 (Q22979_CAEEL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein HIS-39 EMBL CCD70019.1

Gene names

Name:	his-39 EMBL CCD70019.1 WormBase WBGene00001913 WormBase F45F2.2
ORF Names:	CELE_F45F2.2 EMBL CCD70019.1

Organism

Caenorhabditis elegans [Reference proteome] EMBL CCD70019.1

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	108 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling By similarity. SAAS SAAS000558

Ontologies

Keywords
Cellular component	Chromosome Nucleosome core SAAS SAAS000558 Nucleus SAAS SAAS000558
Ligand	DNA-binding
PTM	Isopeptide bond SAAS SAAS000558
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	nucleosome assembly Inferred from electronic annotation. Source: InterPro
Cellular_component	nucleosome Inferred from electronic annotation. Source: UniProtKB-KW nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q22979 [UniParc]. Last modified August 16, 2004. Version 2. Checksum: EB1D79C36513C6F0	FASTA	108	12,164
	10 20 30 40 50 60 MNCCKIFKYL TPNFLHKESY SLYIFRVLKQ VHPDTGVSSK AMSIMNSFVN DVFERIAAEA 70 80 90 100 SRLAHYNKRS TISSREIQTA VRLILPGELA KNAVSEGTNA VTKYTSSK

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." Caenorhabditis elegans Sequencing Consortium Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2 EMBL CCD70019.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FO081223 Genomic DNA. Translation: CCD70019.1.
PIR	T28965.
RefSeq	NP_505201.2. NM_072800.2.
UniGene	Cel.28729.
3D structure databases
HSSP	HSSP built from PDB template 2HIO based on UniProtKB P02279.
ProteinModelPortal	Q22979.
SMR	Q22979. Positions 17-108.
ModBase	Search...
Protein-protein interaction databases
STRING	6239.F45F2.2. Q22979.
Proteomic databases
PaxDb	Q22979.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	F45F2.2; F45F2.2; F45F2.2.
GeneID	191681.
KEGG	cel:CELE_F45F2.2.
UCSC	F45F2.2. c. elegans.
Organism-specific databases
CTD	191681.
WormBase	F45F2.2; CE36851; WBGene00001913; his-39.
Phylogenomic databases
eggNOG	NOG289161.
GeneTree	ENSGT00640000091455.
HOGENOM	HOG000231213.
InParanoid	Q22979.
KO	K11252.
OMA	TQKKEGR.
Family and domain databases
Gene3D	1.10.20.10. 1 hit.
InterPro	IPR009072. Histone-fold. IPR007125. Histone_core_D. IPR000558. Histone_H2B. [Graphical view]
PANTHER	PTHR23428. PTHR23428. 1 hit.
Pfam	PF00125. Histone. 1 hit. [Graphical view]
PRINTS	PR00621. HISTONEH2B.
SMART	SM00427. H2B. 1 hit. [Graphical view]
SUPFAM	SSF47113. Histone-fold. 1 hit.
ProtoNet	Search...
Other
NextBio	949948.

Entry information

Entry name

Q22979_CAEEL

Accession

Primary (citable) accession number: Q22979

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	August 16, 2004
Last modified:	May 1, 2013
This is version 114 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)