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Protein
Submitted name:

Uncharacterized protein

Gene

acd-4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Sodium channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

ReactomeiR-CEL-2672351. Stimuli-sensing channels.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:acd-4Imported
ORF Names:CELE_F28A12.1Imported, F28A12.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF28A12.1; CE09735; WBGene00017879; acd-4.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei60 – 8526HelicalSequence analysisAdd
BLAST
Transmembranei472 – 49625HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ22970.

Expressioni

Gene expression databases

BgeeiWBGene00017879.

Interactioni

Protein-protein interaction databases

DIPiDIP-24777N.
MINTiMINT-1114587.
STRINGi6239.F28A12.1.

Structurei

3D structure databases

ProteinModelPortaliQ22970.
SMRiQ22970. Positions 70-484.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiQ22970.
OMAiHFSTITT.
OrthoDBiEOG091G053J.
PhylomeDBiQ22970.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiPF00858. ASC. 1 hit.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.

Sequencei

Sequence statusi: Complete.

Q22970-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRKRKLSCF VSVKFPVDSV KKLRKTEGVG SVYQETQHFS TITTVNGPRR
60 70 80 90 100
IFYGKRSAQI FWILVVISIL AFLVYQIVIL IQYFYSKPTL SQINFITNEG
110 120 130 140 150
AVYFPSVTVC NLNPVKTSFI KKLNSSGDLS EELLNYLLAT KTNSMYMFNN
160 170 180 190 200
ANIFELKRAH LNALVYLANH PDFEIVNFLN SAQFDCDELF ETCFYGGKQF
210 220 230 240 250
NCCKYMTQSI TSLGRCWELN LRNETDAWLT KKGRSGTSPK TGLQIIANAR
260 270 280 290 300
QSEQFINFHY SSFQENGFRY FIHPPHVSPD LAAEGITVSP SRVVNSAIKT
310 320 330 340 350
VLHDLLNHEN WGNCTSSWPE HYNTNLPYSS SACQALCVSN YFKKLCGCSP
360 370 380 390 400
YSYNIDNNTQ VCLPYEEVIC MMEKMTKSDS NGTVSLDFPF CAECHLACQK
410 420 430 440 450
TSYSSYTSYG DGFNYNSMKW LTRETNRSAS YIRQNIAIIN IHFMELFYTS
460 470 480 490 500
YSQVKATTIL NTFNKIFGLN GLWFGMSVVS LTELILYFTK ISWIAVSSKR
510 520 530 540 550
RQYLFEKKMS EKRKERNIEE AVQEAEISRS RRSSAANLKF LDIESLDDED
560 570 580 590 600
YWYRSSSQLS DSHLDNVIQL AIDFEKPLQR PSAISLPRIS ECCEDFEEED
610
EDENNDLGII IKL
Length:613
Mass (Da):70,419
Last modified:November 1, 1996 - v1
Checksum:i48DEAF8EB1D0AE2E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD70112.1.
PIRiT28952.
RefSeqiNP_505230.1. NM_072829.1.
UniGeneiCel.3853.

Genome annotation databases

EnsemblMetazoaiF28A12.1; F28A12.1; WBGene00017879.
GeneIDi185036.
KEGGicel:CELE_F28A12.1.
UCSCiF28A12.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD70112.1.
PIRiT28952.
RefSeqiNP_505230.1. NM_072829.1.
UniGeneiCel.3853.

3D structure databases

ProteinModelPortaliQ22970.
SMRiQ22970. Positions 70-484.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-24777N.
MINTiMINT-1114587.
STRINGi6239.F28A12.1.

Proteomic databases

PaxDbiQ22970.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF28A12.1; F28A12.1; WBGene00017879.
GeneIDi185036.
KEGGicel:CELE_F28A12.1.
UCSCiF28A12.1. c. elegans.

Organism-specific databases

CTDi185036.
WormBaseiF28A12.1; CE09735; WBGene00017879; acd-4.

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiQ22970.
OMAiHFSTITT.
OrthoDBiEOG091G053J.
PhylomeDBiQ22970.

Enzyme and pathway databases

ReactomeiR-CEL-2672351. Stimuli-sensing channels.

Gene expression databases

BgeeiWBGene00017879.

Family and domain databases

InterProiIPR001873. Na+channel_ASC.
[Graphical view]
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiPF00858. ASC. 1 hit.
[Graphical view]
PRINTSiPR01078. AMINACHANNEL.
ProtoNetiSearch...

Entry informationi

Entry nameiQ22970_CAEEL
AccessioniPrimary (citable) accession number: Q22970
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.