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Protein
Submitted name:

Uncharacterized protein

Gene

acd-4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channel, Sodium channelUniRule annotationSAAS annotation
Biological processIon transport, Sodium transport, Transport
LigandSodium

Enzyme and pathway databases

ReactomeiR-CEL-2672351. Stimuli-sensing channels.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:acd-4Imported
ORF Names:CELE_F28A12.1Imported, F28A12.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF28A12.1; CE09735; WBGene00017879; acd-4.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei60 – 85HelicalSequence analysisAdd BLAST26
Transmembranei472 – 496HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ22970.

Expressioni

Gene expression databases

BgeeiWBGene00017879.

Interactioni

Protein-protein interaction databases

DIPiDIP-24777N.
MINTiMINT-1114587.
STRINGi6239.F28A12.1.

Structurei

3D structure databases

ProteinModelPortaliQ22970.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4294. Eukaryota.
ENOG410ZNFK. LUCA.
GeneTreeiENSGT00760000119120.
HOGENOMiHOG000017615.
InParanoidiQ22970.
OMAiHFSTITT.
OrthoDBiEOG091G053J.
PhylomeDBiQ22970.

Family and domain databases

InterProiView protein in InterPro
IPR001873. ENaC.
PANTHERiPTHR11690. PTHR11690. 1 hit.
PfamiView protein in Pfam
PF00858. ASC. 1 hit.
PRINTSiPR01078. AMINACHANNEL.

Sequencei

Sequence statusi: Complete.

Q22970-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRKRKLSCF VSVKFPVDSV KKLRKTEGVG SVYQETQHFS TITTVNGPRR
60 70 80 90 100
IFYGKRSAQI FWILVVISIL AFLVYQIVIL IQYFYSKPTL SQINFITNEG
110 120 130 140 150
AVYFPSVTVC NLNPVKTSFI KKLNSSGDLS EELLNYLLAT KTNSMYMFNN
160 170 180 190 200
ANIFELKRAH LNALVYLANH PDFEIVNFLN SAQFDCDELF ETCFYGGKQF
210 220 230 240 250
NCCKYMTQSI TSLGRCWELN LRNETDAWLT KKGRSGTSPK TGLQIIANAR
260 270 280 290 300
QSEQFINFHY SSFQENGFRY FIHPPHVSPD LAAEGITVSP SRVVNSAIKT
310 320 330 340 350
VLHDLLNHEN WGNCTSSWPE HYNTNLPYSS SACQALCVSN YFKKLCGCSP
360 370 380 390 400
YSYNIDNNTQ VCLPYEEVIC MMEKMTKSDS NGTVSLDFPF CAECHLACQK
410 420 430 440 450
TSYSSYTSYG DGFNYNSMKW LTRETNRSAS YIRQNIAIIN IHFMELFYTS
460 470 480 490 500
YSQVKATTIL NTFNKIFGLN GLWFGMSVVS LTELILYFTK ISWIAVSSKR
510 520 530 540 550
RQYLFEKKMS EKRKERNIEE AVQEAEISRS RRSSAANLKF LDIESLDDED
560 570 580 590 600
YWYRSSSQLS DSHLDNVIQL AIDFEKPLQR PSAISLPRIS ECCEDFEEED
610
EDENNDLGII IKL
Length:613
Mass (Da):70,419
Last modified:November 1, 1996 - v1
Checksum:i48DEAF8EB1D0AE2E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD70112.1.
PIRiT28952.
RefSeqiNP_505230.1. NM_072829.1.
UniGeneiCel.3853.

Genome annotation databases

EnsemblMetazoaiF28A12.1; F28A12.1; WBGene00017879.
GeneIDi185036.
KEGGicel:CELE_F28A12.1.
UCSCiF28A12.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ22970_CAEEL
AccessioniPrimary (citable) accession number: Q22970
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 25, 2017
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported