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Protein

Homeobox protein ceh-21

Gene

ceh-21

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Probable DNA-binding regulatory protein involved in cell-fate specification.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi284 – 370CUTPROSITE-ProRule annotationAdd BLAST87
DNA bindingi389 – 449HomeoboxPROSITE-ProRule annotationAdd BLAST61

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein ceh-21
Gene namesi
Name:ceh-21
ORF Names:T26C11.6
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiT26C11.6; CE29823; WBGene00000444; ceh-21.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002024081 – 495Homeobox protein ceh-21Add BLAST495

Proteomic databases

EPDiQ22811.
PaxDbiQ22811.
PRIDEiQ22811.

Expressioni

Gene expression databases

BgeeiWBGene00000444.

Interactioni

Protein-protein interaction databases

IntActiQ22811. 2 interactors.
STRINGi6239.T26C11.6.

Structurei

3D structure databases

ProteinModelPortaliQ22811.
SMRiQ22811.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CUT homeobox family.Curated

Keywords - Domaini

Homeobox

Phylogenomic databases

GeneTreeiENSGT00530000063019.
InParanoidiQ22811.
OrthoDBiEOG091G0E7H.

Family and domain databases

InterProiView protein in InterPro
IPR003350. CUT_dom.
IPR009057. Homeobox-like.
IPR001356. Homeobox_dom.
IPR010982. Lambda_DNA-bd_dom.
PfamiView protein in Pfam
PF02376. CUT. 1 hit.
PF00046. Homeobox. 1 hit.
SMARTiView protein in SMART
SM01109. CUT. 1 hit.
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiView protein in PROSITE
PS51042. CUT. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q22811-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQQFQASSG TGSASLREFK TEHEDLREDL PYSTLRTLFG ITLDKDASQA
60 70 80 90 100
LNIALLLYGH NYPQQVVPPE RNYAELDAQL ESVVLEDHTA ESTMEPGVSA
110 120 130 140 150
TVTEQLEEKS DKSSDGDGTS KRLTRSLKSV ENETEEDHEE KEDEAPQSSR
160 170 180 190 200
RESTRLKRKL LESQKTVQTT GNSSRASSKS QEKEVPGTKS QCAPKIRTTP
210 220 230 240 250
EQSKAATKRQ SSTTVRASST CGSSVSSTST VSSPDYTAKK GRATETPKLE
260 270 280 290 300
ELAPKKQSSA TPKPGGEVCV WDGVQIGDLS AQMNAQIGDD EELDTVDIAR
310 320 330 340 350
RILSELKERC IPQTALAEKI LARSQGTLSD LLRMPKPWSV MKNGRATFQR
360 370 380 390 400
MSNWLGLDPD VRRALCFLPK EDVARITGLD EPTPAKRKKT VKVIRLTFTE
410 420 430 440 450
TQLKSLQKSF QQNHRPTREM RQKLSATLEL DFSTVGNFFM NSRRRLRIDQ
460 470 480 490
QISRSSRSTG NGADTEDELD EEDVVVENVI ADATDASNQP GPSHL
Length:495
Mass (Da):54,823
Last modified:June 6, 2002 - v3
Checksum:iC4FFA0984D0DAA08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ427855 mRNA. Translation: CAD20808.1.
FO080541 Genomic DNA. Translation: CCD64528.1.
AF023470 mRNA. Translation: AAB86814.1.
PIRiT28912.
T42240.
RefSeqiNP_508341.2. NM_075940.5.
UniGeneiCel.9167.

Genome annotation databases

EnsemblMetazoaiT26C11.6; T26C11.6; WBGene00000444.
GeneIDi180504.
KEGGicel:CELE_T26C11.6.
UCSCiT26C11.6.2. c. elegans.

Entry informationi

Entry nameiHM21_CAEEL
AccessioniPrimary (citable) accession number: Q22811
Secondary accession number(s): Q8WQE1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: June 6, 2002
Last modified: May 10, 2017
This is version 128 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families