Reviewed, UniProtKB/Swiss-Prot Q22799 (DYL1_CAEEL)

Names and origin

Protein names

Recommended name:
    Dynein light chain 1, cytoplasmic

Gene names

Name:	dlc-1
ORF Names:	T26A5.9

Organism

Caenorhabditis elegans [Complete proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	89 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	May be involved in some aspects of dynein-related intracellular transport and motility. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures By similarity.
Subunit structure	Consists of at least two heavy chains and a number of intermediate and light chains.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the dynein light chain family.

Ontologies

Keywords
Cellular component	Cytoplasm Dynein Microtubule
Molecular function	Motor protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	body morphogenesis Inferred from mutant phenotype. Source: WormBase embryonic development ending in birth or egg hatching Inferred from mutant phenotype. Source: WormBase hermaphrodite genitalia development Inferred from mutant phenotype. Source: WormBase locomotion Inferred from mutant phenotype. Source: WormBase microtubule-based process Inferred from electronic annotation. Source: InterPro morphogenesis of an epithelium Inferred from mutant phenotype. Source: WormBase nematode larval development Inferred from mutant phenotype. Source: WormBase positive regulation of growth rate Inferred from mutant phenotype. Source: WormBase pronuclear migration Inferred from mutant phenotype. Source: WormBase
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell dynein complex Inferred from electronic annotation. Source: UniProtKB-KW microtubule Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	microtubule motor activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
	Q17902	1	EBI-328324,EBI-328330
	Q18529	1	EBI-328324,EBI-314884
	Q19816	1	EBI-328324,EBI-328360
	Q22696	1	EBI-328324,EBI-328387
	Q95QM1	1	EBI-328324,EBI-316840
	Q9U2M6	1	EBI-328324,EBI-328406
	Q9XVX4	1	EBI-328324,EBI-328356
chc-1	P34574	1	EBI-328324,EBI-319001
F10G8.8	O62399	1	EBI-328324,EBI-322231
nhr-31	Q18192	1	EBI-328324,EBI-319458
nhr-4	O45436	1	EBI-328324,EBI-313048
pal-1	P34766	1	EBI-328324,EBI-311911
smo-1	P55853	1	EBI-328324,EBI-313647
spat-1	O45243	1	EBI-328324,EBI-328382
unc-69	Q22276	1	EBI-328324,EBI-320979

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 89	89	Dynein light chain 1, cytoplasmic		PRO_0000195130

Sequences

	Sequence		Length	Mass (Da)
	Q22799-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 72831C3103C2294E	FASTA	89	10,344
	10 20 30 40 50 60 MVDRKAVIKN ADMSDDMQQD AIDCATQALE KYNIEKDIAA YIKKEFDKKY NPTWHCIVGR 70 80 NFGSYVTHET KHFIYFYLGQ VAILLFKSG

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00043 Genomic DNA. Translation: AAC77510.1.
PIR	T34388.
RefSeq	NP_498422.1.
UniGene	Cel.18125
3D structure databases
HSSP	HSSP built from PDB template 1CMI based on UniProtKB Q15701.
SMR	Q22799. Positions 1-89.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:25449N.
IntAct	Q22799. 40 interactions.
Genome annotation databases
Ensembl	T26A5.9. Caenorhabditis elegans. [Contig view]
GeneID	175922.
KEGG	cel:T26A5.9.
Organism-specific databases
WormBase	WBGene00001005. dlc-1.
WormPep	T26A5.9. CE00788. [WorfDB]
Phylogenomic databases
OMA	Q22799. LIASKGH.
Gene expression databases
ArrayExpress	Q22799.
Family and domain databases
InterPro	IPR001372. Dynein_light_1/2. IPR019763. Dynein_light_1/2_CS. [Graphical view]
Gene3D	G3DSA:3.30.740.10. Dynein_light1. 1 hit.
PANTHER	PTHR11886. Dynein_light1. 1 hit.
Pfam	PF01221. Dynein_light. 1 hit. [Graphical view]
ProDom	PD005145. Dynein_light1. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS01239. DYNEIN_LIGHT_1. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	890322.

Entry information

Entry name

DYL1_CAEEL

Accession

Primary (citable) accession number: Q22799

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	June 16, 2009
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project