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Q22355

- Q22355_CAEEL

UniProt

Q22355 - Q22355_CAEEL

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Protein
Submitted name:

Protein AST-1

Gene

ast-1

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: RefGenome

GO - Biological processi

  1. dopaminergic neuron differentiation Source: WormBase
  2. positive regulation of transcription from RNA polymerase II promoter Source: WormBase
  3. transcription from RNA polymerase II promoter Source: GOC
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotation

Enzyme and pathway databases

SignaLinkiQ22355.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein AST-1Imported
Gene namesi
Name:ast-1Imported
ORF Names:CELE_T08H4.3Imported, T08H4.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome II

Organism-specific databases

WormBaseiT08H4.3; CE19576; WBGene00020368; ast-1.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: RefGenome
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ22355.
PRIDEiQ22355.

Interactioni

Protein-protein interaction databases

STRINGi6239.T08H4.3.

Structurei

3D structure databases

ProteinModelPortaliQ22355.
SMRiQ22355. Positions 210-325.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ETS family.UniRule annotation
Contains 1 ETS DNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiNOG242679.
GeneTreeiENSGT00760000118907.
HOGENOMiHOG000022152.
InParanoidiQ22355.
OMAiFNISMNA.
OrthoDBiEOG73V6K8.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR000418. Ets_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00178. Ets. 1 hit.
[Graphical view]
PRINTSiPR00454. ETSDOMAIN.
SMARTiSM00413. ETS. 1 hit.
[Graphical view]
PROSITEiPS00345. ETS_DOMAIN_1. 1 hit.
PS00346. ETS_DOMAIN_2. 1 hit.
PS50061. ETS_DOMAIN_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q22355-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQVVSSATLP PTVASADLAI VGGRSSDEDV IKYSAIQTIK QEQQQQQQQQ
60 70 80 90 100
SNTALPSYNF PFFNGMQNDF PPNRMLYNDN TMQKSENDHF TGMNLSTSAS
110 120 130 140 150
SSGNSTSSKD QSRRQFYTES SNSSGNGAAA TSGSNGSSSS TESKSDVFNI
160 170 180 190 200
SMNAFAATPG SKSEDHNIPS FNMLSSYYTG ALKLSNSTSF ANPDPYQILG
210 220 230 240 250
PTSKNLAHSG SGQTQLWQFL LELLSDKRYS EVITWEGTQG EFKLVDPDEV
260 270 280 290 300
ARKWGERKSK PNMNYDKMSR ALRYYYDKNI MAKVHGKRYA YKFDFQGIAQ
310 320 330 340 350
ALQPPTASHP QDYFNSHAMG RIAPDFSSWT SANYRSLNIA GFNNGSTIFN
360 370
PSVNYSAFGA TGTSNNLSAA RAFPLYR
Length:377
Mass (Da):41,466
Last modified:January 1, 1999 - v2
Checksum:iD78A6BFA2472D409
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO081683 Genomic DNA. Translation: CCD73307.1.
PIRiT34343.
RefSeqiNP_001022326.1. NM_001027155.4.
UniGeneiCel.7048.

Genome annotation databases

EnsemblMetazoaiT08H4.3; T08H4.3; WBGene00020368.
GeneIDi173749.
KEGGicel:CELE_T08H4.3.
UCSCiT08H4.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO081683 Genomic DNA. Translation: CCD73307.1 .
PIRi T34343.
RefSeqi NP_001022326.1. NM_001027155.4.
UniGenei Cel.7048.

3D structure databases

ProteinModelPortali Q22355.
SMRi Q22355. Positions 210-325.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6239.T08H4.3.

Proteomic databases

PaxDbi Q22355.
PRIDEi Q22355.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai T08H4.3 ; T08H4.3 ; WBGene00020368 .
GeneIDi 173749.
KEGGi cel:CELE_T08H4.3.
UCSCi T08H4.3. c. elegans.

Organism-specific databases

CTDi 173749.
WormBasei T08H4.3 ; CE19576 ; WBGene00020368 ; ast-1.

Phylogenomic databases

eggNOGi NOG242679.
GeneTreei ENSGT00760000118907.
HOGENOMi HOG000022152.
InParanoidi Q22355.
OMAi FNISMNA.
OrthoDBi EOG73V6K8.

Enzyme and pathway databases

SignaLinki Q22355.

Miscellaneous databases

NextBioi 880923.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR000418. Ets_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00178. Ets. 1 hit.
[Graphical view ]
PRINTSi PR00454. ETSDOMAIN.
SMARTi SM00413. ETS. 1 hit.
[Graphical view ]
PROSITEi PS00345. ETS_DOMAIN_1. 1 hit.
PS00346. ETS_DOMAIN_2. 1 hit.
PS50061. ETS_DOMAIN_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ22355_CAEEL
AccessioniPrimary (citable) accession number: Q22355
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: January 1, 1999
Last modified: October 29, 2014
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3