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Protein
Submitted name:

Axon STeering defect

Gene

ast-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • dopaminergic neuron differentiation Source: WormBase
  • positive regulation of transcription from RNA polymerase II promoter Source: WormBase
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

SignaLinkiQ22355.

Names & Taxonomyi

Protein namesi
Submitted name:
Axon STeering defectImported
Gene namesi
Name:ast-1Imported
ORF Names:CELE_T08H4.3Imported, T08H4.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiT08H4.3; CE19576; WBGene00020368; ast-1.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ22355.
PRIDEiQ22355.

Interactioni

Protein-protein interaction databases

STRINGi6239.T08H4.3.

Structurei

3D structure databases

ProteinModelPortaliQ22355.
SMRiQ22355. Positions 210-325.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini214 – 29481ETS DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ETS family.UniRule annotationSAAS annotation
Contains 1 ETS DNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiKOG3806. Eukaryota.
ENOG410Z0ZF. LUCA.
GeneTreeiENSGT00760000118907.
HOGENOMiHOG000022152.
InParanoidiQ22355.
OMAiFNISMNA.
OrthoDBiEOG73V6K8.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR000418. Ets_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00178. Ets. 1 hit.
[Graphical view]
PRINTSiPR00454. ETSDOMAIN.
SMARTiSM00413. ETS. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00345. ETS_DOMAIN_1. 1 hit.
PS00346. ETS_DOMAIN_2. 1 hit.
PS50061. ETS_DOMAIN_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q22355-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVVSSATLP PTVASADLAI VGGRSSDEDV IKYSAIQTIK QEQQQQQQQQ
60 70 80 90 100
SNTALPSYNF PFFNGMQNDF PPNRMLYNDN TMQKSENDHF TGMNLSTSAS
110 120 130 140 150
SSGNSTSSKD QSRRQFYTES SNSSGNGAAA TSGSNGSSSS TESKSDVFNI
160 170 180 190 200
SMNAFAATPG SKSEDHNIPS FNMLSSYYTG ALKLSNSTSF ANPDPYQILG
210 220 230 240 250
PTSKNLAHSG SGQTQLWQFL LELLSDKRYS EVITWEGTQG EFKLVDPDEV
260 270 280 290 300
ARKWGERKSK PNMNYDKMSR ALRYYYDKNI MAKVHGKRYA YKFDFQGIAQ
310 320 330 340 350
ALQPPTASHP QDYFNSHAMG RIAPDFSSWT SANYRSLNIA GFNNGSTIFN
360 370
PSVNYSAFGA TGTSNNLSAA RAFPLYR
Length:377
Mass (Da):41,466
Last modified:January 1, 1999 - v2
Checksum:iD78A6BFA2472D409
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CCD73307.1.
PIRiT34343.
RefSeqiNP_001022326.1. NM_001027155.4.
UniGeneiCel.7048.

Genome annotation databases

EnsemblMetazoaiT08H4.3; T08H4.3; WBGene00020368.
GeneIDi173749.
KEGGicel:CELE_T08H4.3.
UCSCiT08H4.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CCD73307.1.
PIRiT34343.
RefSeqiNP_001022326.1. NM_001027155.4.
UniGeneiCel.7048.

3D structure databases

ProteinModelPortaliQ22355.
SMRiQ22355. Positions 210-325.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.T08H4.3.

Proteomic databases

PaxDbiQ22355.
PRIDEiQ22355.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT08H4.3; T08H4.3; WBGene00020368.
GeneIDi173749.
KEGGicel:CELE_T08H4.3.
UCSCiT08H4.3. c. elegans.

Organism-specific databases

CTDi173749.
WormBaseiT08H4.3; CE19576; WBGene00020368; ast-1.

Phylogenomic databases

eggNOGiKOG3806. Eukaryota.
ENOG410Z0ZF. LUCA.
GeneTreeiENSGT00760000118907.
HOGENOMiHOG000022152.
InParanoidiQ22355.
OMAiFNISMNA.
OrthoDBiEOG73V6K8.

Enzyme and pathway databases

SignaLinkiQ22355.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR000418. Ets_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00178. Ets. 1 hit.
[Graphical view]
PRINTSiPR00454. ETSDOMAIN.
SMARTiSM00413. ETS. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00345. ETS_DOMAIN_1. 1 hit.
PS00346. ETS_DOMAIN_2. 1 hit.
PS50061. ETS_DOMAIN_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ22355_CAEEL
AccessioniPrimary (citable) accession number: Q22355
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: January 1, 1999
Last modified: July 6, 2016
This is version 127 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.