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Protein
Submitted name:

Uncharacterized protein

Gene

CELE_T08H10.1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei51 – 511Proton donorUniRule annotation
Sitei80 – 801Lowers pKa of active site TyrUniRule annotation
Binding sitei113 – 1131SubstrateUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-CEL-156590. Glutathione conjugation.
R-CEL-5661270. Catabolism of glucuronate to xylulose-5-phosphate.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:CELE_T08H10.1Imported, T08H10.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiT08H10.1; CE17230; WBGene00020369.

PTM / Processingi

Proteomic databases

EPDiQ22352.
PaxDbiQ22352.
PRIDEiQ22352.

Interactioni

Protein-protein interaction databases

DIPiDIP-25786N.
MINTiMINT-1078852.
STRINGi6239.T08H10.1.

Structurei

3D structure databases

ProteinModelPortaliQ22352.
SMRiQ22352. Positions 6-302.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini18 – 298281Aldo_ket_redInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1577. Eukaryota.
COG0656. LUCA.
GeneTreeiENSGT00760000119041.
HOGENOMiHOG000250272.
InParanoidiQ22352.
OMAiPFKHQEG.
OrthoDBiEOG70KGQF.
PhylomeDBiQ22352.

Family and domain databases

Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 2 hits.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFiPIRSF000097. AKR. 1 hit.
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q22352-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVDSIPLNT GAQLPLFGLG TWQVKDEAEL TVALRAALDA GYRLIDTAHL
60 70 80 90 100
YQNEHIIGKV LHEYISSGKL KREDIFVTSK LPFTAHAPED VPKCVESQLK
110 120 130 140 150
ALQLEYIDLY LIHCPFPFKH QEGSFAPLME NGELAVTEIA HIDTWRALEK
160 170 180 190 200
LYKEGKLKAL GVSNFSCNQL QALYDAAEVK PANQQVECHI YWPQQELRAL
210 220 230 240 250
CKKLGVTVTA YAPLGSPGRK AARPDGVWPE GDPLLEPIVK QLAAKYHKTA
260 270 280 290 300
AQILIRHLTQ HGISTIPKSV SPDRIVENIS TFDFKLSDED MHTLNSIETR
310 320 330
TRLFIADFAV KHPFFPHDDI DTSKVPKVGI RLH
Length:333
Mass (Da):37,315
Last modified:November 1, 1999 - v2
Checksum:i54D0333B45183B09
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD72269.1.
PIRiB89027.
RefSeqiNP_504231.1. NM_071830.5.
UniGeneiCel.2382.

Genome annotation databases

EnsemblMetazoaiT08H10.1; T08H10.1; WBGene00020369.
GeneIDi178844.
KEGGicel:CELE_T08H10.1.
UCSCiT08H10.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CCD72269.1.
PIRiB89027.
RefSeqiNP_504231.1. NM_071830.5.
UniGeneiCel.2382.

3D structure databases

ProteinModelPortaliQ22352.
SMRiQ22352. Positions 6-302.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-25786N.
MINTiMINT-1078852.
STRINGi6239.T08H10.1.

Proteomic databases

EPDiQ22352.
PaxDbiQ22352.
PRIDEiQ22352.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT08H10.1; T08H10.1; WBGene00020369.
GeneIDi178844.
KEGGicel:CELE_T08H10.1.
UCSCiT08H10.1. c. elegans.

Organism-specific databases

CTDi178844.
WormBaseiT08H10.1; CE17230; WBGene00020369.

Phylogenomic databases

eggNOGiKOG1577. Eukaryota.
COG0656. LUCA.
GeneTreeiENSGT00760000119041.
HOGENOMiHOG000250272.
InParanoidiQ22352.
OMAiPFKHQEG.
OrthoDBiEOG70KGQF.
PhylomeDBiQ22352.

Enzyme and pathway databases

ReactomeiR-CEL-156590. Glutathione conjugation.
R-CEL-5661270. Catabolism of glucuronate to xylulose-5-phosphate.

Miscellaneous databases

NextBioi902788.

Family and domain databases

Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 2 hits.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFiPIRSF000097. AKR. 1 hit.
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ22352_CAEEL
AccessioniPrimary (citable) accession number: Q22352
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1999
Last modified: May 11, 2016
This is version 103 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.