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Reviewed, UniProtKB/Swiss-Prot Q22306 (YW12_CAEEL)

Last modified December 15, 2009. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Alternative products · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    UPF0046 protein T07D4.2
Gene names
ORF Names: T07D4.2
OrganismCaenorhabditis elegans [Complete proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length396 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the UPF0046 family.

Ontologies

Keywords
   Coding sequence diversityAlternative splicing
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionhydrolase activity

Inferred from electronic annotation. Source: InterPro

protein binding

Inferred from physical interaction. Source: IntAct

Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]
Isoform b (identifier: Q22306-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Note: No experimental confirmation available.
Isoform a (identifier: Q22306-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-95: MLSPALLKVS...KKTRRKLSNP → MFSKSSNRFG...RESLVRELRT
Note: No experimental confirmation available.
Isoform c (identifier: Q22306-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-24: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 396396UPF0046 protein T07D4.2
PRO_0000053410

Natural variations

Alternative sequence1 – 9595MLSPA…KLSNP → MFSKSSNRFGTTSIFGDQSI KDEYRNRQRRLSLIGGPISG TSPNRRESLVRELRT in isoform a.
VSP_026508
Alternative sequence1 – 2424Missing in isoform c.
VSP_026509

Sequences

Sequence LengthMass (Da)Tools
Isoform b [UniParc].

Last modified July 10, 2007. Version 3.
Checksum: C4C9FCE2368484D1

FASTA39644,869
        10         20         30         40         50         60 
MLSPALLKVS LNRRSSAPVP QDEKMMFHSR NRAASYLQPM IEDQELIGFN RDRRRSSGSI 

        70         80         90        100        110        120 
IVDSFELGNA SPSRRGSIAS GIPMDKKTRR KLSNPVSLHQ YTEDPTLAWE MLKEKRPVKP 

       130        140        150        160        170        180 
VRQMRLDTPV KPDHVRFVCI GCTHGEQFDI SKLPPGDVLL VAGDFTSCGL PNEVHNFNKL 

       190        200        210        220        230        240 
LGKLKYSYKV VIGGNHECTF DDTFLKLKQE SEPKEMALKQ ALLSAIHSDS KGGISAKDLL 

       250        260        270        280        290        300 
SNAIYLEDNV IELFGITIYG TPWQPKVDNW AFNLSRGQQL LDKWNLIPAG VDVLLTHTPP 

       310        320        330        340        350        360 
LGHGDMMNNG QRMGCAELLN TVFKRVRPKY HVFGHIHEGY GCTTDGYTKF INCCMCNENL 

       370        380        390 
DLKNEPVIFD IPVHPHTKQF YIQNVKKIHK RFQKKK 

« Hide

Isoform a.

Checksum: 7B7CBDAF01869FB0
Show »

FASTA35640,515
Isoform c.

Checksum: CE5FB2A70F825412
Show »

FASTA37242,250

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], ALTERNATIVE SPLICING.
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

Z50071 Genomic DNA. Translation: CAA90405.3.
Z50071 Genomic DNA. Translation: CAH04718.2.
Z50071 Genomic DNA. Translation: CAL64000.2.
PIRT24660.
RefSeqNP_001022323.2.
NP_001022324.2.
NP_001076633.1.
UniGeneCel.14429

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

DIPDIP-26139N.
IntActQ22306. 11 interactions.
STRINGQ22306.

Genome annotation databases

EnsemblT07D4.2b; T07D4.2b; T07D4.2; Caenorhabditis elegans. [Genome view]
GeneID174416.
KEGGcel:T07D4.2.
UCSCT07D4.2b. c. elegans.

Organism-specific databases

CTD174416.
WormBaseWBGene00011579. T07D4.2.
WormPepT07D4.2a. CE40620. [WorfDB]
T07D4.2b. CE40621. [WorfDB]
T07D4.2c. CE40622. [WorfDB]

Phylogenomic databases

HOGENOMHBG385841.
InParanoidQ22306.
OMADRREANI.

Gene expression databases

ArrayExpressQ22306.

Family and domain databases

InterProIPR004843. M-pesterase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio883930.

Entry information

Entry nameYW12_CAEEL
AccessionPrimary (citable) accession number: Q22306
Secondary accession number(s): A0FLR0, Q6BEU9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 10, 2007
Last modified: December 15, 2009
This is version 57 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectCaenorhabditis annotation project

Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormPep

SIMILARITY comments

Index of protein domains and families

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Alternative products · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents