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Q22224 (Q22224_CAEEL) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 105. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Protein ACR-14 EMBL CAA91304.2
Gene names
Name:acr-14 EMBL CAA91304.2 WormBase WBGene00000053 WormBase T05C12.2
ORF Names:CELE_T05C12.2 EMBL CAA91304.2
OrganismCaenorhabditis elegans [Reference proteome] EMBL CAA91304.2
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length500 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification] RuleBase RU000687

Sequences

Sequence LengthMass (Da)Tools
Q22224 [UniParc].

Last modified May 1, 2000. Version 2.
Checksum: 20BD4CBF19614892

FASTA50057,675
        10         20         30         40         50         60 
MSFVFFILLT FYIQVKGSVD EYRLLQYLKE NYDSFERPVE NSSAPLDVKV RFLLNQIMDV 

        70         80         90        100        110        120 
DEKNQVMSIL AYMDYHWNDY KLTWDPKLFG GIRDVRFSGD DDASFKLWRP DVLLFNSVSE 

       130        140        150        160        170        180 
SFDSTYSSRF IVSSNGDVQQ NPPGIFRFVC QIDVTYYPFD KQTCFLKLGS WTYNGQYINL 

       190        200        210        220        230        240 
DFLLTQIIGL HGIPIVVEPE RSSTNYASYF VNESIDLQVY LQNGEWDLEG TPGKRVVQKF 

       250        260        270        280        290        300 
GTDEYHELYF YIHIRRRTLA YGINLIIPSL VISMMTILGF TLPPDACEKI TLETTVLLSV 

       310        320        330        340        350        360 
IFFLQMVSST SPPQSQSVPI LAAFFSCCLM LVACSCVFTV LTLSLHHRKP ETHEMSPTMR 

       370        380        390        400        410        420 
KIFIDWLPYI LCMCKPDHPK TPKPKVLGKS IAPIHRLSTI PMLNLPRVSQ TTFPDKNVFV 

       430        440        450        460        470        480 
YHEVPAVIKN TSRICAELLI IERDIEKMLD KIEEDTKEDM LRSEWRFAAM AVDRLCLYVF 

       490        500 
SAFITMITCG LIVPHILANI

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References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
Caenorhabditis elegans Sequencing Consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2 EMBL CAA91304.2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Z66500 Genomic DNA. Translation: CAA91304.2.
PIRT24504.
RefSeqNP_495716.1. NM_063315.1.
UniGeneCel.16093.

3D structure databases

HSSPHSSP built from PDB template 1OED based on UniProtKB P02711.
ProteinModelPortalQ22224.
SMRQ22224. Positions 18-353.
ModBaseSearch...

Protein-protein interaction databases

STRING6239.T05C12.2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaT05C12.2; T05C12.2; T05C12.2.
GeneID191601.
KEGGcel:CELE_T05C12.2.
UCSCT05C12.2. c. elegans.

Organism-specific databases

CTD191601.
WormBaseT05C12.2; CE25099; WBGene00000053; acr-14.

Phylogenomic databases

eggNOGNOG304378.
GeneTreeENSGT00630000089708.
HOGENOMHOG000006756.
InParanoidQ22224.
OMAMSILAYM.

Family and domain databases

Gene3D2.70.170.10. 1 hit.
InterProIPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
IPR002394. Nicotinic_acetylcholine_rcpt.
[Graphical view]
PANTHERPTHR18945. PTHR18945. 1 hit.
PfamPF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
[Graphical view]
PRINTSPR00254. NICOTINICR.
PR00252. NRIONCHANNEL.
SUPFAMSSF90112. Neu_channel_TM. 1 hit.
SSF63712. Neur_chan_LBD. 1 hit.
PROSITEPS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio949632.

Entry information

Entry nameQ22224_CAEEL
AccessionPrimary (citable) accession number: Q22224
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: May 1, 2000
Last modified: May 1, 2013
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info