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Protein
Submitted name:

NeuroPeptide Receptor family

Gene

npr-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
NeuroPeptide Receptor familyImported
Gene namesi
Name:npr-2Imported
ORF Names:CELE_T05A1.1Imported, T05A1.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiT05A1.1b; CE32925; WBGene00003808; npr-2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 51HelicalSequence analysisAdd BLAST27
Transmembranei63 – 89HelicalSequence analysisAdd BLAST27
Transmembranei101 – 122HelicalSequence analysisAdd BLAST22
Transmembranei143 – 161HelicalSequence analysisAdd BLAST19
Transmembranei189 – 213HelicalSequence analysisAdd BLAST25
Transmembranei276 – 298HelicalSequence analysisAdd BLAST23
Transmembranei318 – 343HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ22188.

Expressioni

Gene expression databases

BgeeiWBGene00003808.
ExpressionAtlasiQ22188. differential.

Interactioni

Protein-protein interaction databases

STRINGi6239.T05A1.1a.

Structurei

3D structure databases

ProteinModelPortaliQ22188.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 340G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST298

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118781.
HOGENOMiHOG000020311.
OrthoDBiEOG091G06MF.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000611. NPY_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01012. NRPEPTIDEYR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q22188-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINETEETCD RYIDKHPDMT NEPTVLVTFS LLYLHIFLLG ILGNSAVLYL
60 70 80 90 100
TMKHRQLQTV QNIFILNLCA SNVLMCLTSL PITFITNVYK QWFFSSPVCK
110 120 130 140 150
LIPLVQGASI FVSTFSLSAI ALDRYNLVVR PHKQKLSSRS AMMIALLIWV
160 170 180 190 200
ISVVVCMPYG WYMDVEKLNG LCGEYCSEHW PLAEVRKGYT FLVLITQFLF
210 220 230 240 250
PFATMAFCYY NIFSRLRQRV ETKLKKLSER SQLLENSTTC GTTNHIVSIN
260 270 280 290 300
AEAVQNGLEN KQRLAVLAQQ RRTTTILSCM VLLFAFTWLP HNVVTLMIEY
310 320 330 340 350
DGFFFHSDET SATSTDHTYI VSMTAHLISM LTNVTNPFLY AWLNPMFKEM
360 370 380
LIKTLRGGSK SPKPADIKQT SFIRMPNSGA PSQSSYL
Length:387
Mass (Da):44,128
Last modified:March 1, 2003 - v2
Checksum:i195C02A8A65772FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92481.2.
PIRiT24487.
RefSeqiNP_872089.1. NM_182289.3.
UniGeneiCel.12399.

Genome annotation databases

EnsemblMetazoaiT05A1.1b; T05A1.1b; WBGene00003808.
GeneIDi177790.
UCSCiT05A1.1a. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92481.2.
PIRiT24487.
RefSeqiNP_872089.1. NM_182289.3.
UniGeneiCel.12399.

3D structure databases

ProteinModelPortaliQ22188.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.T05A1.1a.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ22188.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT05A1.1b; T05A1.1b; WBGene00003808.
GeneIDi177790.
UCSCiT05A1.1a. c. elegans.

Organism-specific databases

CTDi177790.
WormBaseiT05A1.1b; CE32925; WBGene00003808; npr-2.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00760000118781.
HOGENOMiHOG000020311.
OrthoDBiEOG091G06MF.

Gene expression databases

BgeeiWBGene00003808.
ExpressionAtlasiQ22188. differential.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000611. NPY_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01012. NRPEPTIDEYR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ22188_CAEEL
AccessioniPrimary (citable) accession number: Q22188
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: March 1, 2003
Last modified: November 30, 2016
This is version 122 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.