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Protein
Submitted name:

NeuroPeptide Receptor family

Gene

npr-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
NeuroPeptide Receptor familyImported
Gene namesi
Name:npr-2Imported
ORF Names:CELE_T05A1.1Imported, T05A1.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiT05A1.1b ; CE32925 ; WBGene00003808 ; npr-2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 51HelicalSequence analysisAdd BLAST27
Transmembranei63 – 89HelicalSequence analysisAdd BLAST27
Transmembranei101 – 122HelicalSequence analysisAdd BLAST22
Transmembranei143 – 161HelicalSequence analysisAdd BLAST19
Transmembranei189 – 213HelicalSequence analysisAdd BLAST25
Transmembranei276 – 298HelicalSequence analysisAdd BLAST23
Transmembranei318 – 343HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiWBGene00003808
ExpressionAtlasiQ22188 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ22188
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 340G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST298

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili217 – 237Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00920000148949
HOGENOMiHOG000020311
OrthoDBiEOG091G06MF

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000611 NPY_rcpt
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR01012 NRPEPTIDEYR
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q22188-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINETEETCD RYIDKHPDMT NEPTVLVTFS LLYLHIFLLG ILGNSAVLYL
60 70 80 90 100
TMKHRQLQTV QNIFILNLCA SNVLMCLTSL PITFITNVYK QWFFSSPVCK
110 120 130 140 150
LIPLVQGASI FVSTFSLSAI ALDRYNLVVR PHKQKLSSRS AMMIALLIWV
160 170 180 190 200
ISVVVCMPYG WYMDVEKLNG LCGEYCSEHW PLAEVRKGYT FLVLITQFLF
210 220 230 240 250
PFATMAFCYY NIFSRLRQRV ETKLKKLSER SQLLENSTTC GTTNHIVSIN
260 270 280 290 300
AEAVQNGLEN KQRLAVLAQQ RRTTTILSCM VLLFAFTWLP HNVVTLMIEY
310 320 330 340 350
DGFFFHSDET SATSTDHTYI VSMTAHLISM LTNVTNPFLY AWLNPMFKEM
360 370 380
LIKTLRGGSK SPKPADIKQT SFIRMPNSGA PSQSSYL
Length:387
Mass (Da):44,128
Last modified:March 1, 2003 - v2
Checksum:i195C02A8A65772FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA Translation: CAA92481.2
PIRiT24487
RefSeqiNP_872089.1, NM_182289.3
UniGeneiCel.12399

Genome annotation databases

EnsemblMetazoaiT05A1.1b; T05A1.1b; WBGene00003808
GeneIDi177790
UCSCiT05A1.1a c. elegans

Similar proteinsi

Entry informationi

Entry nameiQ22188_CAEEL
AccessioniPrimary (citable) accession number: Q22188
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: March 1, 2003
Last modified: June 20, 2018
This is version 132 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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