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Protein
Submitted name:

ELRR (Extracellular Leucine-Rich Repeat) ONly

Gene

lron-14

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-CEL-109704. PI3K Cascade.
R-CEL-1679131. Trafficking and processing of endosomal TLR.
R-CEL-168138. Toll Like Receptor 9 (TLR9) Cascade.
R-CEL-168181. Toll Like Receptor 7/8 (TLR7/8) Cascade.
R-CEL-975155. MyD88 dependent cascade initiated on endosome.

Names & Taxonomyi

Protein namesi
Submitted name:
ELRR (Extracellular Leucine-Rich Repeat) ONlyImported
Gene namesi
Name:lron-14Imported
ORF Names:CELE_T05A1.3Imported, T05A1.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiT05A1.3a; CE32926; WBGene00011454; lron-14.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei692 – 71726HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 747724Sequence analysisPRO_5004200825Add
BLAST

Proteomic databases

PaxDbiQ22187.

Expressioni

Gene expression databases

ExpressionAtlasiQ22187. baseline.

Interactioni

Protein-protein interaction databases

STRINGi6239.T05A1.3a.

Structurei

3D structure databases

ProteinModelPortaliQ22187.
SMRiQ22187. Positions 29-572.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00730000111167.
HOGENOMiHOG000199593.
InParanoidiQ22187.
OMAiKECECRF.
OrthoDBiEOG7X6M0V.
PhylomeDBiQ22187.

Family and domain databases

Gene3Di3.80.10.10. 3 hits.
InterProiIPR002131. Gphrmn_rcpt_fam.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PANTHERiPTHR24372. PTHR24372. 1 hit.
PfamiPF13855. LRR_8. 3 hits.
[Graphical view]
SMARTiSM00369. LRR_TYP. 9 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 2 hits.

Sequencei

Sequence statusi: Complete.

Q22187-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVLPLLHLF LISSLQIAPT ATSSPSQFPC PTRCQCYADN EQNQQVHLIC
60 70 80 90 100
KWEQLNVTTL QLARPDLVRT LTIKCPYHSP KVSTPPHSLF QGFRNLDRLE
110 120 130 140 150
LDRCLIDTVP EGLFAGLGQL YSLIVKNAKI TDFPREIFAH VPNLMTLDLS
160 170 180 190 200
GNRLRIEPYS LRSLQNLIHL DVSDNDIGFL TNTLISLTKL KVITMNNNKI
210 220 230 240 250
TNIDFRRFPE NLTDLSIRHN LVSTIHYVPA SARNLKRLDL AGNRMEFVGG
260 270 280 290 300
LTTGAVNVLP AELKHVDLSN NKLTYLHDHA FEHLTNLILL DLKNNSLKEV
310 320 330 340 350
KSSSFAGSKF QVKLFLSENP LLCHCNHKWL MDSSAKNISI GDLQTIECLN
360 370 380 390 400
ILKPEKKMLL TLAHSRNQLL CKYSNMCEAD CECCQKKECE CRFECPPTCK
410 420 430 440 450
CLRSADVSIV RTSQNIMVCD KLRWDKLGKF PSPLTQLHMN QTDWKIFETE
460 470 480 490 500
KLKELSNLRA LKITNSKMTS VEMEKLTDLA NLTHLEITSS AITSIPETIT
510 520 530 540 550
KLPSLTHLYL SDNPLDQLSS TSLNHLDGLK KIRLGGNFSR FACDCESPSD
560 570 580 590 600
FQRWLMRRIN RAKIDDIDDL YCDLNGHGTV WMLEALPGTN ESVCLDPTEE
610 620 630 640 650
TKQWMTFVEN AQKGIMERVY TSTESTTKSE KTMMTTTLKK SILDTMDELE
660 670 680 690 700
GVKSTEKISN KVISTTTVPT TTPRYRKKYK NYDNEPHKFV NVLIFLLFLC
710 720 730 740
VIILIISIGV TVYLKFWHPE ELLMKRRKKE RLRPEIQREE EPLQHLD
Length:747
Mass (Da):85,401
Last modified:March 1, 2003 - v2
Checksum:iCAB68B9B2EEB9337
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92480.2.
PIRiT24486.
RefSeqiNP_001255400.1. NM_001268471.1.
UniGeneiCel.12397.

Genome annotation databases

EnsemblMetazoaiT05A1.3a; T05A1.3a; WBGene00011454.
GeneIDi188075.
KEGGicel:CELE_T05A1.3.
UCSCiT05A1.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA92480.2.
PIRiT24486.
RefSeqiNP_001255400.1. NM_001268471.1.
UniGeneiCel.12397.

3D structure databases

ProteinModelPortaliQ22187.
SMRiQ22187. Positions 29-572.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.T05A1.3a.

Proteomic databases

PaxDbiQ22187.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT05A1.3a; T05A1.3a; WBGene00011454.
GeneIDi188075.
KEGGicel:CELE_T05A1.3.
UCSCiT05A1.3. c. elegans.

Organism-specific databases

CTDi188075.
WormBaseiT05A1.3a; CE32926; WBGene00011454; lron-14.

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00730000111167.
HOGENOMiHOG000199593.
InParanoidiQ22187.
OMAiKECECRF.
OrthoDBiEOG7X6M0V.
PhylomeDBiQ22187.

Enzyme and pathway databases

ReactomeiR-CEL-109704. PI3K Cascade.
R-CEL-1679131. Trafficking and processing of endosomal TLR.
R-CEL-168138. Toll Like Receptor 9 (TLR9) Cascade.
R-CEL-168181. Toll Like Receptor 7/8 (TLR7/8) Cascade.
R-CEL-975155. MyD88 dependent cascade initiated on endosome.

Gene expression databases

ExpressionAtlasiQ22187. baseline.

Family and domain databases

Gene3Di3.80.10.10. 3 hits.
InterProiIPR002131. Gphrmn_rcpt_fam.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PANTHERiPTHR24372. PTHR24372. 1 hit.
PfamiPF13855. LRR_8. 3 hits.
[Graphical view]
SMARTiSM00369. LRR_TYP. 9 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ22187_CAEEL
AccessioniPrimary (citable) accession number: Q22187
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: March 1, 2003
Last modified: July 6, 2016
This is version 118 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.