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Q22181

- UGT56_CAEEL

UniProt

Q22181 - UGT56_CAEEL

Protein

Putative UDP-glucuronosyltransferase ugt-56

Gene

ugt-56

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 2 (11 Apr 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

    GO - Molecular functioni

    1. glucuronosyltransferase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Protein family/group databases

    CAZyiGT1. Glycosyltransferase Family 1.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative UDP-glucuronosyltransferase ugt-56 (EC:2.4.1.17)
    Short name:
    UDPGT 56
    Gene namesi
    Name:ugt-56
    Synonyms:ugt12
    ORF Names:T04H1.8
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome V

    Organism-specific databases

    WormBaseiT04H1.8; CE31985; WBGene00011453; ugt-56.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2020Sequence AnalysisAdd
    BLAST
    Chaini21 – 524504Putative UDP-glucuronosyltransferase ugt-56PRO_0000036052Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi125 – 1251N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi277 – 2771N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi335 – 3351N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi6239.T04H1.8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ22181.
    SMRiQ22181. Positions 205-459.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei488 – 50821HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UDP-glycosyltransferase family.Curated

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG237243.
    GeneTreeiENSGT00740000115656.
    HOGENOMiHOG000022454.
    InParanoidiQ22181.
    KOiK00699.
    OMAiATSSHMP.
    OrthoDBiEOG78H3T2.
    PhylomeDBiQ22181.

    Family and domain databases

    InterProiIPR002213. UDP_glucos_trans.
    [Graphical view]
    PANTHERiPTHR11926. PTHR11926. 1 hit.
    PfamiPF00201. UDPGT. 1 hit.
    [Graphical view]
    PROSITEiPS00375. UDPGT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q22181-1 [UniParc]FASTAAdd to Basket

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    MLWAFIVWLG ALCIYGSAFD ILIYAPRMMQ SHVYFTARIA NVLAARGHKV    50
    TVIDNVFRYD VDNELSSDIH EIISVEPSPE VTKLLNTGSL PTILWNSKAS 100
    PEEQRTIMEG LGHVHRLQCT HLIENSTLIP KLQEIKFDFA IHEVFDSCGV 150
    GILEVIGVQK TVIVSSTGPM DVVPITLGIS DTLNTPSLLS DYGSYLSFFE 200
    KRRNLKFLSG MLNFHEMQDS MISPLFKKYY GLKKPTGEIM RQANLLFYNI 250
    HEGSDGMRMR GRRSFDIGGI AFKDQKNLTM EYQTLLSDPR PKVLVSFGTA 300
    ATSSHMPQNL KNSLMTAMKQ MNNVLFIWKY EMEDNFTKQE ELTTNIIFKK 350
    FLPQTDLLAS SKIDLFVTHC GQNSLLEAFN SGVRVLAVPL FGDQHRNAKL 400
    AFENGLIEIL PKSDIETPAK IVKAVKTGLE PNAKLDQNIV LISSLLRNSK 450
    ENAENLLIST IEATYSTEFP PNFSKFPKNY HPNTLVRLID SSIALVFMLF 500
    IFVFVNHFRK NYVGFKYPLS FSTK 524
    Length:524
    Mass (Da):59,284
    Last modified:April 11, 2003 - v2
    Checksum:i2CDA85E24BBDF3CC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z78200 Genomic DNA. Translation: CAB01585.2.
    PIRiT24478.
    RefSeqiNP_506074.2. NM_073673.4.
    UniGeneiCel.2497.

    Genome annotation databases

    EnsemblMetazoaiT04H1.8; T04H1.8; WBGene00011453.
    GeneIDi188073.
    KEGGicel:CELE_T04H1.8.
    UCSCiT04H1.8. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z78200 Genomic DNA. Translation: CAB01585.2 .
    PIRi T24478.
    RefSeqi NP_506074.2. NM_073673.4.
    UniGenei Cel.2497.

    3D structure databases

    ProteinModelPortali Q22181.
    SMRi Q22181. Positions 205-459.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6239.T04H1.8.

    Protein family/group databases

    CAZyi GT1. Glycosyltransferase Family 1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai T04H1.8 ; T04H1.8 ; WBGene00011453 .
    GeneIDi 188073.
    KEGGi cel:CELE_T04H1.8.
    UCSCi T04H1.8. c. elegans.

    Organism-specific databases

    CTDi 188073.
    WormBasei T04H1.8 ; CE31985 ; WBGene00011453 ; ugt-56.

    Phylogenomic databases

    eggNOGi NOG237243.
    GeneTreei ENSGT00740000115656.
    HOGENOMi HOG000022454.
    InParanoidi Q22181.
    KOi K00699.
    OMAi ATSSHMP.
    OrthoDBi EOG78H3T2.
    PhylomeDBi Q22181.

    Miscellaneous databases

    NextBioi 937504.

    Family and domain databases

    InterProi IPR002213. UDP_glucos_trans.
    [Graphical view ]
    PANTHERi PTHR11926. PTHR11926. 1 hit.
    Pfami PF00201. UDPGT. 1 hit.
    [Graphical view ]
    PROSITEi PS00375. UDPGT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiUGT56_CAEEL
    AccessioniPrimary (citable) accession number: Q22181
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: April 11, 2003
    Last modified: October 1, 2014
    This is version 94 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3