Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q22181 (UGT56_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative UDP-glucuronosyltransferase ugt-56

Short name=UDPGT 56
EC=2.4.1.17
Gene names
Name:ugt-56
Synonyms:ugt12
ORF Names:T04H1.8
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length524 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the UDP-glycosyltransferase family.

Ontologies

Keywords
   Cellular componentMembrane
   DomainSignal
Transmembrane
Transmembrane helix
   Molecular functionGlycosyltransferase
Transferase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionglucuronosyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential
Chain21 – 524504Putative UDP-glucuronosyltransferase ugt-56
PRO_0000036052

Regions

Transmembrane488 – 50821Helical; Potential

Amino acid modifications

Glycosylation1251N-linked (GlcNAc...) Potential
Glycosylation2771N-linked (GlcNAc...) Potential
Glycosylation3351N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q22181 [UniParc].

Last modified April 11, 2003. Version 2.
Checksum: 2CDA85E24BBDF3CC

FASTA52459,284
        10         20         30         40         50         60 
MLWAFIVWLG ALCIYGSAFD ILIYAPRMMQ SHVYFTARIA NVLAARGHKV TVIDNVFRYD 

        70         80         90        100        110        120 
VDNELSSDIH EIISVEPSPE VTKLLNTGSL PTILWNSKAS PEEQRTIMEG LGHVHRLQCT 

       130        140        150        160        170        180 
HLIENSTLIP KLQEIKFDFA IHEVFDSCGV GILEVIGVQK TVIVSSTGPM DVVPITLGIS 

       190        200        210        220        230        240 
DTLNTPSLLS DYGSYLSFFE KRRNLKFLSG MLNFHEMQDS MISPLFKKYY GLKKPTGEIM 

       250        260        270        280        290        300 
RQANLLFYNI HEGSDGMRMR GRRSFDIGGI AFKDQKNLTM EYQTLLSDPR PKVLVSFGTA 

       310        320        330        340        350        360 
ATSSHMPQNL KNSLMTAMKQ MNNVLFIWKY EMEDNFTKQE ELTTNIIFKK FLPQTDLLAS 

       370        380        390        400        410        420 
SKIDLFVTHC GQNSLLEAFN SGVRVLAVPL FGDQHRNAKL AFENGLIEIL PKSDIETPAK 

       430        440        450        460        470        480 
IVKAVKTGLE PNAKLDQNIV LISSLLRNSK ENAENLLIST IEATYSTEFP PNFSKFPKNY 

       490        500        510        520 
HPNTLVRLID SSIALVFMLF IFVFVNHFRK NYVGFKYPLS FSTK 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z78200 Genomic DNA. Translation: CAB01585.2.
PIRT24478.
RefSeqNP_506074.2. NM_073673.4.
UniGeneCel.2497.

3D structure databases

ProteinModelPortalQ22181.
SMRQ22181. Positions 205-459.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6239.T04H1.8.

Protein family/group databases

CAZyGT1. Glycosyltransferase Family 1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaT04H1.8; T04H1.8; WBGene00011453.
GeneID188073.
KEGGcel:CELE_T04H1.8.
UCSCT04H1.8. c. elegans.

Organism-specific databases

CTD188073.
WormBaseT04H1.8; CE31985; WBGene00011453; ugt-56.

Phylogenomic databases

eggNOGNOG237243.
GeneTreeENSGT00740000115656.
HOGENOMHOG000022454.
InParanoidQ22181.
KOK00699.
OMAATSSHMP.
OrthoDBEOG78H3T2.
PhylomeDBQ22181.

Family and domain databases

InterProIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERPTHR11926. PTHR11926. 1 hit.
PfamPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEPS00375. UDPGT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio937504.

Entry information

Entry nameUGT56_CAEEL
AccessionPrimary (citable) accession number: Q22181
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: April 11, 2003
Last modified: June 11, 2014
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase