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Q22181

- UGT56_CAEEL

UniProt

Q22181 - UGT56_CAEEL

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Protein

Putative UDP-glucuronosyltransferase ugt-56

Gene

ugt-56

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

GO - Molecular functioni

  1. glucuronosyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative UDP-glucuronosyltransferase ugt-56 (EC:2.4.1.17)
Short name:
UDPGT 56
Gene namesi
Name:ugt-56
Synonyms:ugt12
ORF Names:T04H1.8
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome V

Organism-specific databases

WormBaseiT04H1.8; CE31985; WBGene00011453; ugt-56.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence AnalysisAdd
BLAST
Chaini21 – 524504Putative UDP-glucuronosyltransferase ugt-56PRO_0000036052Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi125 – 1251N-linked (GlcNAc...)Sequence Analysis
Glycosylationi277 – 2771N-linked (GlcNAc...)Sequence Analysis
Glycosylationi335 – 3351N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi6239.T04H1.8.

Structurei

3D structure databases

ProteinModelPortaliQ22181.
SMRiQ22181. Positions 205-459.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei488 – 50821HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG237243.
GeneTreeiENSGT00760000119404.
HOGENOMiHOG000022454.
InParanoidiQ22181.
KOiK00699.
OMAiATSSHMP.
OrthoDBiEOG78H3T2.
PhylomeDBiQ22181.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q22181-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLWAFIVWLG ALCIYGSAFD ILIYAPRMMQ SHVYFTARIA NVLAARGHKV
60 70 80 90 100
TVIDNVFRYD VDNELSSDIH EIISVEPSPE VTKLLNTGSL PTILWNSKAS
110 120 130 140 150
PEEQRTIMEG LGHVHRLQCT HLIENSTLIP KLQEIKFDFA IHEVFDSCGV
160 170 180 190 200
GILEVIGVQK TVIVSSTGPM DVVPITLGIS DTLNTPSLLS DYGSYLSFFE
210 220 230 240 250
KRRNLKFLSG MLNFHEMQDS MISPLFKKYY GLKKPTGEIM RQANLLFYNI
260 270 280 290 300
HEGSDGMRMR GRRSFDIGGI AFKDQKNLTM EYQTLLSDPR PKVLVSFGTA
310 320 330 340 350
ATSSHMPQNL KNSLMTAMKQ MNNVLFIWKY EMEDNFTKQE ELTTNIIFKK
360 370 380 390 400
FLPQTDLLAS SKIDLFVTHC GQNSLLEAFN SGVRVLAVPL FGDQHRNAKL
410 420 430 440 450
AFENGLIEIL PKSDIETPAK IVKAVKTGLE PNAKLDQNIV LISSLLRNSK
460 470 480 490 500
ENAENLLIST IEATYSTEFP PNFSKFPKNY HPNTLVRLID SSIALVFMLF
510 520
IFVFVNHFRK NYVGFKYPLS FSTK
Length:524
Mass (Da):59,284
Last modified:April 11, 2003 - v2
Checksum:i2CDA85E24BBDF3CC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z78200 Genomic DNA. Translation: CAB01585.2.
PIRiT24478.
RefSeqiNP_506074.2. NM_073673.4.
UniGeneiCel.2497.

Genome annotation databases

EnsemblMetazoaiT04H1.8; T04H1.8; WBGene00011453.
GeneIDi188073.
KEGGicel:CELE_T04H1.8.
UCSCiT04H1.8. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z78200 Genomic DNA. Translation: CAB01585.2 .
PIRi T24478.
RefSeqi NP_506074.2. NM_073673.4.
UniGenei Cel.2497.

3D structure databases

ProteinModelPortali Q22181.
SMRi Q22181. Positions 205-459.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6239.T04H1.8.

Protein family/group databases

CAZyi GT1. Glycosyltransferase Family 1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai T04H1.8 ; T04H1.8 ; WBGene00011453 .
GeneIDi 188073.
KEGGi cel:CELE_T04H1.8.
UCSCi T04H1.8. c. elegans.

Organism-specific databases

CTDi 188073.
WormBasei T04H1.8 ; CE31985 ; WBGene00011453 ; ugt-56.

Phylogenomic databases

eggNOGi NOG237243.
GeneTreei ENSGT00760000119404.
HOGENOMi HOG000022454.
InParanoidi Q22181.
KOi K00699.
OMAi ATSSHMP.
OrthoDBi EOG78H3T2.
PhylomeDBi Q22181.

Miscellaneous databases

NextBioi 937504.

Family and domain databases

InterProi IPR002213. UDP_glucos_trans.
[Graphical view ]
PANTHERi PTHR11926. PTHR11926. 1 hit.
Pfami PF00201. UDPGT. 1 hit.
[Graphical view ]
PROSITEi PS00375. UDPGT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiUGT56_CAEEL
AccessioniPrimary (citable) accession number: Q22181
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: April 11, 2003
Last modified: October 29, 2014
This is version 95 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3