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Protein

Putative UDP-glucuronosyltransferase ugt-56

Gene

ugt-56

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative UDP-glucuronosyltransferase ugt-56 (EC:2.4.1.17)
Short name:
UDPGT 56
Gene namesi
Name:ugt-56
Synonyms:ugt12
ORF Names:T04H1.8
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiT04H1.8; CE31985; WBGene00011453; ugt-56.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei488 – 50821HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence AnalysisAdd
BLAST
Chaini21 – 524504Putative UDP-glucuronosyltransferase ugt-56PRO_0000036052Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi125 – 1251N-linked (GlcNAc...)Sequence Analysis
Glycosylationi277 – 2771N-linked (GlcNAc...)Sequence Analysis
Glycosylationi335 – 3351N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi6239.T04H1.8.

Structurei

3D structure databases

ProteinModelPortaliQ22181.
SMRiQ22181. Positions 205-459.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG237243.
GeneTreeiENSGT00770000120708.
HOGENOMiHOG000022454.
InParanoidiQ22181.
KOiK00699.
OMAiATSSHMP.
OrthoDBiEOG78H3T2.
PhylomeDBiQ22181.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q22181-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLWAFIVWLG ALCIYGSAFD ILIYAPRMMQ SHVYFTARIA NVLAARGHKV
60 70 80 90 100
TVIDNVFRYD VDNELSSDIH EIISVEPSPE VTKLLNTGSL PTILWNSKAS
110 120 130 140 150
PEEQRTIMEG LGHVHRLQCT HLIENSTLIP KLQEIKFDFA IHEVFDSCGV
160 170 180 190 200
GILEVIGVQK TVIVSSTGPM DVVPITLGIS DTLNTPSLLS DYGSYLSFFE
210 220 230 240 250
KRRNLKFLSG MLNFHEMQDS MISPLFKKYY GLKKPTGEIM RQANLLFYNI
260 270 280 290 300
HEGSDGMRMR GRRSFDIGGI AFKDQKNLTM EYQTLLSDPR PKVLVSFGTA
310 320 330 340 350
ATSSHMPQNL KNSLMTAMKQ MNNVLFIWKY EMEDNFTKQE ELTTNIIFKK
360 370 380 390 400
FLPQTDLLAS SKIDLFVTHC GQNSLLEAFN SGVRVLAVPL FGDQHRNAKL
410 420 430 440 450
AFENGLIEIL PKSDIETPAK IVKAVKTGLE PNAKLDQNIV LISSLLRNSK
460 470 480 490 500
ENAENLLIST IEATYSTEFP PNFSKFPKNY HPNTLVRLID SSIALVFMLF
510 520
IFVFVNHFRK NYVGFKYPLS FSTK
Length:524
Mass (Da):59,284
Last modified:April 11, 2003 - v2
Checksum:i2CDA85E24BBDF3CC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z78200 Genomic DNA. Translation: CAB01585.2.
PIRiT24478.
RefSeqiNP_506074.2. NM_073673.4.
UniGeneiCel.2497.

Genome annotation databases

EnsemblMetazoaiT04H1.8; T04H1.8; WBGene00011453.
GeneIDi188073.
KEGGicel:CELE_T04H1.8.
UCSCiT04H1.8. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z78200 Genomic DNA. Translation: CAB01585.2.
PIRiT24478.
RefSeqiNP_506074.2. NM_073673.4.
UniGeneiCel.2497.

3D structure databases

ProteinModelPortaliQ22181.
SMRiQ22181. Positions 205-459.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.T04H1.8.

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT04H1.8; T04H1.8; WBGene00011453.
GeneIDi188073.
KEGGicel:CELE_T04H1.8.
UCSCiT04H1.8. c. elegans.

Organism-specific databases

CTDi188073.
WormBaseiT04H1.8; CE31985; WBGene00011453; ugt-56.

Phylogenomic databases

eggNOGiNOG237243.
GeneTreeiENSGT00770000120708.
HOGENOMiHOG000022454.
InParanoidiQ22181.
KOiK00699.
OMAiATSSHMP.
OrthoDBiEOG78H3T2.
PhylomeDBiQ22181.

Miscellaneous databases

NextBioi937504.
PROiQ22181.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiUGT56_CAEEL
AccessioniPrimary (citable) accession number: Q22181
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: April 11, 2003
Last modified: May 27, 2015
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.