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Protein
Submitted name:

Ligand-Gated ion Channel

Gene

lgc-16

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channelUniRule annotation
Biological processIon transport, Transport

Enzyme and pathway databases

ReactomeiR-CEL-112314. Neurotransmitter receptors and postsynaptic signal transmission.

Names & Taxonomyi

Protein namesi
Submitted name:
Ligand-Gated ion ChannelImported
Gene namesi
Name:lgc-16Imported
ORF Names:CELE_T01H10.5Imported, T01H10.5Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiT01H10.5; CE36664; WBGene00011358; lgc-16.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei262 – 284HelicalSequence analysisAdd BLAST23
Transmembranei293 – 311HelicalSequence analysisAdd BLAST19
Transmembranei323 – 347HelicalSequence analysisAdd BLAST25
Transmembranei368 – 398HelicalSequence analysisAdd BLAST31

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500420063518 – 401Sequence analysisAdd BLAST384

Proteomic databases

PaxDbiQ22083.

Interactioni

Protein-protein interaction databases

STRINGi6239.T01H10.5.

Structurei

3D structure databases

ProteinModelPortaliQ22083.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 260Neur_chan_LBDInterPro annotationAdd BLAST182

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3645. Eukaryota.
ENOG410XQGR. LUCA.
GeneTreeiENSGT00790000122957.
HOGENOMiHOG000015989.
InParanoidiQ22083.
OMAiCESSSIT.
OrthoDBiEOG091G1E94.
PhylomeDBiQ22083.

Family and domain databases

Gene3Di1.20.58.390. 1 hit.
2.70.170.10. 1 hit.
InterProiView protein in InterPro
IPR006202. Neur_chan_lig-bd.
IPR036734. Neur_chan_lig-bd_sf.
IPR006201. Neur_channel.
IPR036719. Neuro-gated_channel_TM_sf.
IPR018000. Neurotransmitter_ion_chnl_CS.
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiView protein in Pfam
PF02931. Neur_chan_LBD. 1 hit.
PRINTSiPR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
PROSITEiView protein in PROSITE
PS00236. NEUROTR_ION_CHANNEL. 1 hit.

Sequencei

Sequence statusi: Complete.

Q22083-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYLGFIVTLF SFSDISAFYH DPGLYAPGWI DYLNLQENLT NDLFANYDPT
60 70 80 90 100
ISTVYADIAD WEPLGDNPRT IDRWNYTILL YYLKLVEVQE PAEKVSVVLE
110 120 130 140 150
LVERWYDPRL SWNISLYSNV STIFARQEKV WSPTLSPFGV NEIIDFRDQD
160 170 180 190 200
FRLISIDFTG YLNDYLSVRV SANCPMDVSR FPFDSQTCQI RFCLPIFNIR
210 220 230 240 250
QVKILNEIYE GILQEKIIKT MGNSEWKVVS LTNRVEQLKY DDDYGNMDLA
260 270 280 290 300
VFEITIRRNP LYYIYMIVFP SFVINGISIV GIFLKSADKM SKLNVGLTNI
310 320 330 340 350
MTMTFILGVM ADKIPRTGSI PLLGIYIIIN LLIMIIAITV VVLITELRQW
360 370 380 390 400
AVPRLKLKKS YMSRKLETFL GSPIEYTCAI LLEFLTTANF FVMIGFWFED

L
Length:401
Mass (Da):46,518
Last modified:September 13, 2004 - v2
Checksum:iC081506BABCAC7A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAA91539.2.
PIRiT24327.
RefSeqiNP_510027.2. NM_077626.2.
UniGeneiCel.27523.

Genome annotation databases

EnsemblMetazoaiT01H10.5; T01H10.5; WBGene00011358.
GeneIDi187975.
KEGGicel:CELE_T01H10.5.
UCSCiT01H10.5. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ22083_CAEEL
AccessioniPrimary (citable) accession number: Q22083
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: September 13, 2004
Last modified: November 22, 2017
This is version 137 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported