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Protein
Submitted name:

Ligand-Gated ion Channel

Gene

lgc-15

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotation

Keywords - Biological processi

Ion transport, Transport

Enzyme and pathway databases

ReactomeiR-CEL-975298. Ligand-gated ion channel transport.

Names & Taxonomyi

Protein namesi
Submitted name:
Ligand-Gated ion ChannelImported
Gene namesi
Name:lgc-15Imported
ORF Names:CELE_T01H10.3Imported, T01H10.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiT01H10.3; CE36663; WBGene00011356; lgc-15.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei261 – 28323HelicalSequence analysisAdd
BLAST
Transmembranei292 – 31019HelicalSequence analysisAdd
BLAST
Transmembranei322 – 34625HelicalSequence analysisAdd
BLAST
Transmembranei367 – 39731HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ22081.
PRIDEiQ22081.

Structurei

3D structure databases

ProteinModelPortaliQ22081.
SMRiQ22081. Positions 38-386.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini36 – 259224Neur_chan_LBDInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3645. Eukaryota.
ENOG410XQGR. LUCA.
GeneTreeiENSGT00790000122957.
HOGENOMiHOG000015989.
InParanoidiQ22081.
OMAiYTILLYS.
PhylomeDBiQ22081.

Family and domain databases

Gene3Di1.20.120.370. 1 hit.
2.70.170.10. 1 hit.
InterProiIPR027361. Acetylcholine_rcpt_TM.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
[Graphical view]
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiPF02931. Neur_chan_LBD. 1 hit.
[Graphical view]
PRINTSiPR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
PROSITEiPS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q22081-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYFTATFLTY ISHVSSIYYN HSLYVPKYYD FLETQTNLTK NLFSGYDATI
60 70 80 90 100
SPVYTKVDPT QPLGHDPDAP GRWNYTLLLF SLKLVEVTEP QEKVSVVMEV
110 120 130 140 150
MEYWFDARLT WNKEDYDDIA SIYTRQANVW SPTLSAFGVS ELVDLRDTDF
160 170 180 190 200
RLVGITSYGM VNTYVSVLVS ANCPMDVYKF PFDYQTCQIR FCIPVFTSYE
210 220 230 240 250
VEIFNEIYAG VLTSNAWKTM GNSEWNLVNL THRVETLKYD DGFANLDLGT
260 270 280 290 300
FEIKIRRNPL YYIYMIIFPS FIINVVSIIG VFLKGADKMS KLNVGLTNIM
310 320 330 340 350
TMTFILGVMA DKIPRTGTIP LLGVYIITNL VIMLIAIGIV TVINELRRCA
360 370 380 390
SPVLKRKQTK LSRKLESFIG TPLEYTCAAI LELLTFANFA IMIGFWLGD
Length:399
Mass (Da):45,597
Last modified:September 13, 2004 - v2
Checksum:i80B693DF206F5412
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAA91538.2.
PIRiT24326.
RefSeqiNP_510025.2. NM_077624.2.
UniGeneiCel.27522.

Genome annotation databases

EnsemblMetazoaiT01H10.3; T01H10.3; WBGene00011356.
GeneIDi187973.
KEGGicel:CELE_T01H10.3.
UCSCiT01H10.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAA91538.2.
PIRiT24326.
RefSeqiNP_510025.2. NM_077624.2.
UniGeneiCel.27522.

3D structure databases

ProteinModelPortaliQ22081.
SMRiQ22081. Positions 38-386.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ22081.
PRIDEiQ22081.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT01H10.3; T01H10.3; WBGene00011356.
GeneIDi187973.
KEGGicel:CELE_T01H10.3.
UCSCiT01H10.3. c. elegans.

Organism-specific databases

CTDi187973.
WormBaseiT01H10.3; CE36663; WBGene00011356; lgc-15.

Phylogenomic databases

eggNOGiKOG3645. Eukaryota.
ENOG410XQGR. LUCA.
GeneTreeiENSGT00790000122957.
HOGENOMiHOG000015989.
InParanoidiQ22081.
OMAiYTILLYS.
PhylomeDBiQ22081.

Enzyme and pathway databases

ReactomeiR-CEL-975298. Ligand-gated ion channel transport.

Family and domain databases

Gene3Di1.20.120.370. 1 hit.
2.70.170.10. 1 hit.
InterProiIPR027361. Acetylcholine_rcpt_TM.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
[Graphical view]
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiPF02931. Neur_chan_LBD. 1 hit.
[Graphical view]
PRINTSiPR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
PROSITEiPS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ22081_CAEEL
AccessioniPrimary (citable) accession number: Q22081
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: September 13, 2004
Last modified: June 8, 2016
This is version 131 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.