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Protein
Submitted name:

Ligand-Gated ion Channel

Gene

lgc-14

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channelUniRule annotation
Biological processIon transport, Transport

Enzyme and pathway databases

ReactomeiR-CEL-112314. Neurotransmitter receptors and postsynaptic signal transmission.

Names & Taxonomyi

Protein namesi
Submitted name:
Ligand-Gated ion ChannelImported
Gene namesi
Name:lgc-14Imported
ORF Names:CELE_T01H10.2Imported, T01H10.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiT01H10.2; CE36662; WBGene00011355; lgc-14.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei260 – 282HelicalSequence analysisAdd BLAST23
Transmembranei321 – 345HelicalSequence analysisAdd BLAST25
Transmembranei372 – 396HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ22080.

Expressioni

Gene expression databases

BgeeiWBGene00011355.

Interactioni

Protein-protein interaction databases

STRINGi6239.T01H10.2.

Structurei

3D structure databases

ProteinModelPortaliQ22080.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 257Neur_chan_LBDInterPro annotationAdd BLAST223

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3645. Eukaryota.
ENOG410XQGR. LUCA.
GeneTreeiENSGT00790000122957.
HOGENOMiHOG000015989.
InParanoidiQ22080.
OMAiYDYISVR.
OrthoDBiEOG091G0CMK.
PhylomeDBiQ22080.

Family and domain databases

Gene3Di1.20.58.390. 1 hit.
2.70.170.10. 1 hit.
InterProiView protein in InterPro
IPR006202. Neur_chan_lig-bd.
IPR036734. Neur_chan_lig-bd_sf.
IPR006201. Neur_channel.
IPR036719. Neuro-gated_channel_TM_sf.
IPR018000. Neurotransmitter_ion_chnl_CS.
PANTHERiPTHR18945. PTHR18945. 1 hit.
PfamiView protein in Pfam
PF02931. Neur_chan_LBD. 1 hit.
PRINTSiPR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
PROSITEiView protein in PROSITE
PS00236. NEUROTR_ION_CHANNEL. 1 hit.

Sequencei

Sequence statusi: Complete.

Q22080-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFFVTFTVIF IGSHALYYNP ELYVPKYHDF IESQTNLTRD LFNGYDPTVS
60 70 80 90 100
PVYSKIDPLQ PLGYDPDAPK RYNYSIMLYS LKLVEVNEPA EKVAVVMEIM
110 120 130 140 150
EYWYDIRLSW NASLYDDIDT FYTRQSNVWS PTLSAFGADE LVDLRDPDFR
160 170 180 190 200
MVCVNSNGYI YDYISVRVSS SCPMNVYKFP FDYQTCQIKF CLPIFNSVEI
210 220 230 240 250
QIFNEIYVGV LMSDLWETMG NSEWKLTNLS NRVETLQYND GFGNLDLGIF
260 270 280 290 300
EITIKRNPLY YIYMIIFPSF IINVVSIIGV FLKGADKMSR LNVGLTNIMT
310 320 330 340 350
MTFILGVMAD KIPRTGTIPM LGVYIIVNLA IMIIAIGIVT MITELRHWLA
360 370 380 390 400
PFLKRNETKF SRKLETFIGP PLEFTCAIIL EVFTCAIFGV MIGFWLGDDK
Length:400
Mass (Da):46,143
Last modified:September 13, 2004 - v3
Checksum:i16515D62CD6EA7BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAA91537.3.
PIRiT24325.
RefSeqiNP_510024.2. NM_077623.2.
UniGeneiCel.438.

Genome annotation databases

EnsemblMetazoaiT01H10.2; T01H10.2; WBGene00011355.
GeneIDi187972.
KEGGicel:CELE_T01H10.2.
UCSCiT01H10.2. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ22080_CAEEL
AccessioniPrimary (citable) accession number: Q22080
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: September 13, 2004
Last modified: November 22, 2017
This is version 137 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported