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Protein
Submitted name:

Uncharacterized protein

Gene

dma-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • axon extension involved in axon guidance Source: GO_Central
  • dendrite morphogenesis Source: WormBase
  • regulation of axonogenesis Source: GO_Central
  • Roundabout signaling pathway Source: GO_Central
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:dma-1Imported
ORF Names:CELE_T01G9.3Imported, T01G9.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiT01G9.3; CE06340; WBGene00011345; dma-1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei506 – 53025HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • dendrite membrane Source: WormBase
  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: WormBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 603584Sequence analysisPRO_5004200250Add
BLAST

Proteomic databases

PaxDbiQ22075.
PRIDEiQ22075.

Expressioni

Gene expression databases

BgeeiWBGene00011345.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ22075. 2 interactions.
STRINGi6239.T01G9.3.

Structurei

3D structure databases

ProteinModelPortaliQ22075.
SMRiQ22075. Positions 23-487.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini438 – 49154LRRCTInterPro annotationAdd
BLAST

Keywords - Domaini

Leucine-rich repeatSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00760000118777.
HOGENOMiHOG000017308.
InParanoidiQ22075.
OMAiLTMANTH.
OrthoDBiEOG091G04LN.
PhylomeDBiQ22075.

Family and domain databases

Gene3Di3.80.10.10. 2 hits.
InterProiIPR000483. Cys-rich_flank_reg_C.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF13855. LRR_8. 2 hits.
[Graphical view]
SMARTiSM00369. LRR_TYP. 9 hits.
SM00082. LRRCT. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 2 hits.
PROSITEiPS51450. LRR. 13 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q22075-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISYILLLFL SFLVLCSIAL PSSCPNLCEC DQNDSSWSVY CRKAIINDTI
60 70 80 90 100
YAEILNQLPL TLRSLHIQPP SNRIGSNKLR WNDNINRFAQ LRVLRLINCQ
110 120 130 140 150
IPAMSRSIRL PSLEVLDLHS NNIEHATMSN FGGMPKLRVL DLSSNHLNIL
160 170 180 190 200
PTGVFTYLRA LRSLSLSNNT ISDLSTNLLR GLNSLRVLRL DRNPIPIEHI
210 220 230 240 250
NELFTDVSQL DELYLNHCNL SSIYSLALDR IPQLRQLGIG GNNLKMVPTK
260 270 280 290 300
ELRSLPQLSV LDLSHNSIQE ITACAFCNTN ISKLDLSHNL LGISKDSPFN
310 320 330 340 350
EDAFRTMPLR HLDLSFNHMN DFDSKWLGWA QEELTSIALS GNFLKNFEES
360 370 380 390 400
WTYTLKSLIH LELAYNHIKF IPVQLPSRYY HLISLNISGN ELTYLPDNIN
410 420 430 440 450
TLLPNVKTFD ITANRFHTFS HTDLAFLNNV EQVYVDGNPW DCSCAIQGLQ
460 470 480 490 500
VHMRDRYAMR HILNYDNVRC ATPSLVEGHS VLAITDVNDC AVLFGARYGL
510 520 530 540 550
TQTSEMLILL AGVLLFAALL LMILGCIYFL RERQYKGSYV TREHSRTPLT
560 570 580 590 600
MANTHSCSSS TNDTHGPLSP PFDPFLVSTE TFKATPPLIP PAPPKPGSSY

FGI
Length:603
Mass (Da):68,046
Last modified:November 1, 1996 - v1
Checksum:i268AF1D42127DE0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAB00050.1.
PIRiT24315.
RefSeqiNP_492253.1. NM_059852.5.
UniGeneiCel.120.

Genome annotation databases

EnsemblMetazoaiT01G9.3; T01G9.3; WBGene00011345.
GeneIDi187968.
KEGGicel:CELE_T01G9.3.
UCSCiT01G9.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAB00050.1.
PIRiT24315.
RefSeqiNP_492253.1. NM_059852.5.
UniGeneiCel.120.

3D structure databases

ProteinModelPortaliQ22075.
SMRiQ22075. Positions 23-487.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ22075. 2 interactions.
STRINGi6239.T01G9.3.

Proteomic databases

PaxDbiQ22075.
PRIDEiQ22075.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT01G9.3; T01G9.3; WBGene00011345.
GeneIDi187968.
KEGGicel:CELE_T01G9.3.
UCSCiT01G9.3. c. elegans.

Organism-specific databases

CTDi187968.
WormBaseiT01G9.3; CE06340; WBGene00011345; dma-1.

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00760000118777.
HOGENOMiHOG000017308.
InParanoidiQ22075.
OMAiLTMANTH.
OrthoDBiEOG091G04LN.
PhylomeDBiQ22075.

Gene expression databases

BgeeiWBGene00011345.

Family and domain databases

Gene3Di3.80.10.10. 2 hits.
InterProiIPR000483. Cys-rich_flank_reg_C.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
[Graphical view]
PfamiPF13855. LRR_8. 2 hits.
[Graphical view]
SMARTiSM00369. LRR_TYP. 9 hits.
SM00082. LRRCT. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 2 hits.
PROSITEiPS51450. LRR. 13 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ22075_CAEEL
AccessioniPrimary (citable) accession number: Q22075
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.