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Protein
Submitted name:

Uncharacterized protein

Gene

egl-43

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • nucleic acid binding Source: InterPro
  • transcription factor activity, sequence-specific DNA binding Source: WormBase

GO - Biological processi

  • regulation of cell migration Source: WormBase
  • regulation of neuron differentiation Source: WormBase
  • regulation of transcription, DNA-templated Source: WormBase

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:egl-43Imported
ORF Names:CELE_R53.3Imported, R53.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiR53.3a; CE03572; WBGene00001207; egl-43.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

EPDiQ22024.
PaxDbiQ22024.
PeptideAtlasiQ22024.

Expressioni

Gene expression databases

BgeeiWBGene00001207.
ExpressionAtlasiQ22024. baseline.

Interactioni

Protein-protein interaction databases

IntActiQ22024. 33 interactors.
STRINGi6239.R53.3a.

Structurei

3D structure databases

ProteinModelPortaliQ22024.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini159 – 186C2H2-typeInterPro annotationAdd BLAST28
Domaini187 – 214C2H2-typeInterPro annotationAdd BLAST28
Domaini444 – 471C2H2-typeInterPro annotationAdd BLAST28
Domaini472 – 500C2H2-typeInterPro annotationAdd BLAST29

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00530000063676.
InParanoidiQ22024.
OMAiSHIHCSL.
OrthoDBiEOG091G0BYE.
PhylomeDBiQ22024.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiView protein in InterPro
IPR013087. Znf_C2H2_type.
IPR013083. Znf_RING/FYVE/PHD.
SMARTiView protein in SMART
SM00355. ZnF_C2H2. 5 hits.
SUPFAMiSSF57667. SSF57667. 2 hits.
PROSITEiView protein in PROSITE
PS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.

Sequencei

Sequence statusi: Complete.

Q22024-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIDTDFLTS VEVKEDELHG NVLIAVTQIA LGRTIGVIDK ATPNDSNALL
60 70 80 90 100
ILNLIKEADD GEDANICMRQ EDRKTFLQTS KIINIGERLL LQRLSEEECD
110 120 130 140 150
EEDQDDLENL ILLKDEDRPD STQSCTKSSS EDSNLNGFEE YIREHGELVP
160 170 180 190 200
GQTPPDGSHK CGVCPKSFSS ASGLKQHSHI HCSLKPFRCH LCPKSYTQFS
210 220 230 240 250
NLCRHRRVHS DGWTCPTCQS QMPSQAALTK HRPVCEMTAL YKPLMAQLAG
260 270 280 290 300
LSGAGGLGSV PYWPHILQMA TQAPHFPLAF LAANPEAYKL MQQTTCASPD
310 320 330 340 350
AECSSGHASE SSPTTTEPVD LTATPKPPST SEMETTSKSD DGEDRDSIGD
360 370 380 390 400
SGNDDDDDSE AGVLDESSTT TSTKKRPTSH TISDILAAPQ LGAQALNSTF
410 420 430 440 450
LGMLQRSLNY NPAVPSPHSF LRAMSGAKAS SSPSSSSGSG KDRYTCKFCQ
460 470 480 490 500
KVFPRSANLT RHLRTHTGEQ PYKCQYCERS FSISSNLQRH VRNIHNKPNT
510 520 530 540
SLTPHNHHRQ RSLHNSTSTS TTTTTVHHPL LHLPGTSVPV PKV
Length:543
Mass (Da):59,357
Last modified:November 1, 1996 - v1
Checksum:iE3A287994095DA82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAA91353.1.
PIRiE88280.
RefSeqiNP_001022288.1. NM_001027117.4.
UniGeneiCel.15534.

Genome annotation databases

EnsemblMetazoaiR53.3a; R53.3a; WBGene00001207.
GeneIDi174552.
KEGGicel:CELE_R53.3.
UCSCiR53.3a. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ22024_CAEEL
AccessioniPrimary (citable) accession number: Q22024
Secondary accession number(s): Q22023
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: August 30, 2017
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported