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Protein
Submitted name:

Uncharacterized protein

Gene

egl-43

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • regulation of cell migration Source: WormBase
  • regulation of neuron differentiation Source: WormBase
  • regulation of transcription, DNA-templated Source: WormBase
Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-CEL-3214841. PKMTs methylate histone lysines.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:egl-43Imported
ORF Names:CELE_R53.3Imported, R53.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiR53.3a; CE03572; WBGene00001207; egl-43.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: WormBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ22024.
PRIDEiQ22024.

Expressioni

Gene expression databases

ExpressionAtlasiQ22024. baseline.

Interactioni

Protein-protein interaction databases

IntActiQ22024. 33 interactions.
STRINGi6239.R53.3a.

Structurei

3D structure databases

ProteinModelPortaliQ22024.
SMRiQ22024. Positions 36-93, 117-243, 444-492.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini159 – 18628C2H2-typeInterPro annotationAdd
BLAST
Domaini187 – 21428C2H2-typeInterPro annotationAdd
BLAST
Domaini444 – 47128C2H2-typeInterPro annotationAdd
BLAST
Domaini472 – 50029C2H2-typeInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00530000063676.
InParanoidiQ22024.
OMAiSHIHCSL.
OrthoDBiEOG72G16H.
PhylomeDBiQ22024.

Family and domain databases

Gene3Di3.30.160.60. 4 hits.
InterProiIPR030413. Evi1/Prdm16.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR24393. PTHR24393. 1 hit.
PfamiPF00096. zf-C2H2. 2 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 5 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q22024-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIDTDFLTS VEVKEDELHG NVLIAVTQIA LGRTIGVIDK ATPNDSNALL
60 70 80 90 100
ILNLIKEADD GEDANICMRQ EDRKTFLQTS KIINIGERLL LQRLSEEECD
110 120 130 140 150
EEDQDDLENL ILLKDEDRPD STQSCTKSSS EDSNLNGFEE YIREHGELVP
160 170 180 190 200
GQTPPDGSHK CGVCPKSFSS ASGLKQHSHI HCSLKPFRCH LCPKSYTQFS
210 220 230 240 250
NLCRHRRVHS DGWTCPTCQS QMPSQAALTK HRPVCEMTAL YKPLMAQLAG
260 270 280 290 300
LSGAGGLGSV PYWPHILQMA TQAPHFPLAF LAANPEAYKL MQQTTCASPD
310 320 330 340 350
AECSSGHASE SSPTTTEPVD LTATPKPPST SEMETTSKSD DGEDRDSIGD
360 370 380 390 400
SGNDDDDDSE AGVLDESSTT TSTKKRPTSH TISDILAAPQ LGAQALNSTF
410 420 430 440 450
LGMLQRSLNY NPAVPSPHSF LRAMSGAKAS SSPSSSSGSG KDRYTCKFCQ
460 470 480 490 500
KVFPRSANLT RHLRTHTGEQ PYKCQYCERS FSISSNLQRH VRNIHNKPNT
510 520 530 540
SLTPHNHHRQ RSLHNSTSTS TTTTTVHHPL LHLPGTSVPV PKV
Length:543
Mass (Da):59,357
Last modified:November 1, 1996 - v1
Checksum:iE3A287994095DA82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAA91353.1.
PIRiE88280.
RefSeqiNP_001022288.1. NM_001027117.4.
UniGeneiCel.15534.

Genome annotation databases

EnsemblMetazoaiR53.3a; R53.3a; WBGene00001207.
GeneIDi174552.
KEGGicel:CELE_R53.3.
UCSCiR53.3a. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAA91353.1.
PIRiE88280.
RefSeqiNP_001022288.1. NM_001027117.4.
UniGeneiCel.15534.

3D structure databases

ProteinModelPortaliQ22024.
SMRiQ22024. Positions 36-93, 117-243, 444-492.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ22024. 33 interactions.
STRINGi6239.R53.3a.

Proteomic databases

PaxDbiQ22024.
PRIDEiQ22024.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiR53.3a; R53.3a; WBGene00001207.
GeneIDi174552.
KEGGicel:CELE_R53.3.
UCSCiR53.3a. c. elegans.

Organism-specific databases

CTDi174552.
WormBaseiR53.3a; CE03572; WBGene00001207; egl-43.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00530000063676.
InParanoidiQ22024.
OMAiSHIHCSL.
OrthoDBiEOG72G16H.
PhylomeDBiQ22024.

Enzyme and pathway databases

ReactomeiR-CEL-3214841. PKMTs methylate histone lysines.

Miscellaneous databases

NextBioi884518.

Gene expression databases

ExpressionAtlasiQ22024. baseline.

Family and domain databases

Gene3Di3.30.160.60. 4 hits.
InterProiIPR030413. Evi1/Prdm16.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR24393. PTHR24393. 1 hit.
PfamiPF00096. zf-C2H2. 2 hits.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 5 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ22024_CAEEL
AccessioniPrimary (citable) accession number: Q22024
Secondary accession number(s): Q22023
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 16, 2016
This is version 130 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.