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Q21ZD5 (G6PI_RHOFD) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:Rfer_1127
OrganismRhodoferax ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118) [Complete proteome] [HAMAP]
Taxonomic identifier338969 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAlbidiferax

Protein attributes

Sequence length522 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 522522Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000252641

Sites

Active site3511Proton donor By similarity
Active site3821 By similarity
Active site4911 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q21ZD5 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: FE252622A86DFF91

FASTA52256,544
        10         20         30         40         50         60 
MTPTRCDRTP AWGALQAAYQ TQGRAFDLRR AFALDAGRFE AFSQGAPHVF ADLSKNLIDA 

        70         80         90        100        110        120 
GTEQQLLELA RQTGLEQHRD AMFAGEKINT TEQRAVMHWL LRTPPADPAM PAQSVHRHMA 

       130        140        150        160        170        180 
ETLHEVHTTL EAMLAFAEAV RADETITDIV NIGIGGSDLG PQMAVLALDA FVLPGKRFHF 

       190        200        210        220        230        240 
VSNVDGHELA AVLRRLKPQS TLFLIASKTF TTIETMTNAR SAKAWFEAQG GTDIARHFAA 

       250        260        270        280        290        300 
LTTNVAAANN FGISTTFGFW DWVGGRYSVW SAIGLPLAIA IGAVGFRDFL AGAHAMDRHF 

       310        320        330        340        350        360 
ATVPLAQNLP VRLGLLDVWY RNFHGFTSRS IAPYHSALKR YPAYLQQLEM ESNGKRVDAH 

       370        380        390        400        410        420 
GEALPYGTAP VLWGEPGTNG QHAYFQMLHQ GTDVVPVEFV AVKQAAHDLP GHHDLLLANV 

       430        440        450        460        470        480 
LAQAQALMVG QADAGGHKNF PGNRPSTFLL LDALTPASLG ALIALQEHRV FVSGSVWGIN 

       490        500        510        520 
SFDQWGVELG KVLAKDVAVR LSSGNVTGLD GSTAGLLARL RA 

« Hide

References

[1]"Complete sequence of chromosome of Rhodoferax ferrireducens DSM 15236."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. expand/collapse author list , Kyrpides N., Ivanova N., Richardson P.
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 15236 / ATCC BAA-621 / T118.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000267 Genomic DNA. Translation: ABD68868.1.
RefSeqYP_522399.1. NC_007908.1.

3D structure databases

ProteinModelPortalQ21ZD5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING338969.Rfer_1127.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD68868; ABD68868; Rfer_1127.
GeneID3963433.
KEGGrfr:Rfer_1127.
PATRIC23234801. VBIRhoFer131161_1425.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMALKMHFVS.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycAFER338969:GHU9-1130-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_RHOFD
AccessionPrimary (citable) accession number: Q21ZD5
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: April 18, 2006
Last modified: February 19, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways