Q21Z42 (Q21Z42_RHOFD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	Rfer_1227

Organism

Rhodoferax ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118) [Complete proteome] [HAMAP]

Taxonomic identifier

338969 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Albidiferax

Protein attributes

Sequence length	1084 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q21Z42 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 45B3DCC31FC119E9	FASTA	1,084	118,798
	10 20 30 40 50 60 MACSLETVVP ATEPASVPAY CELHCLSNFS FGRGASHPEE LVARAAALGY AALALTDECS 70 80 90 100 110 120 VAGVVRAHTE AKKLGLKLLP GAEFAVTQAD GAGGGALEAG FRLVALPHDL QAWGDLCEFI 130 140 150 160 170 180 TQARRAAPKG QYRLLWQDAP WALLGGCEVL LGLPSALHFE AACAITTRAR ALFGSNLWLL 190 200 210 220 230 240 VELLLAPDDT LQGQRLQQLA RLTGVPLVAA GNVHMHVRSR KPLQDVLSAV RLGQPVFDCG 250 260 270 280 290 300 RALQPNAEAH LRSRQRLAAI YSPDVLANTL TVAARCTFSL DELRYQYPLE TVLEGLSAAQ 310 320 330 340 350 360 TLRRYAAEGA LNRYPQGTPA SVQQQLDHEL ALITELHFEM YFLTVHDIVR FARSRHILCQ 370 380 390 400 410 420 GRGSAANSAV CYCLGVTEVD PSRMNMLFER FISRERNEPP DIDVDFEHQR REEVIQYIYA 430 440 450 460 470 480 KYGRERAALS AVVISYRPRS ALRDVGRALA VPEALISALA KEHPGMYSRT VLVERLQSAL 490 500 510 520 530 540 ALLAADVAPP AECLQLWLDL STQLQRFPRH LSQHPGGFVL TRGKLTRLVP VENAAMPERS 550 560 570 580 590 600 IIQWDKDDLD AMGLLKVDVL ALGMLSAIRR CLDLISVQRG TPFSMQDIPP EDLATYDMIC 610 620 630 640 650 660 QADTVGVFQI ESRAQMSMLP RLKPRCFYDL VVEVAIVRPG PIQGGMVHPY LKAREHPEQV 670 680 690 700 710 720 PYPSPALQEV LKRTLGVPIF QEQVMQIAMA AADFSAGESD SLRRSMAAWK RQGGVHKFYD 730 740 750 760 770 780 RLVGGMLKNG YSLEFAEQIF KQIEGFGEYG FPESHAASFA LLVYVSSWLK RHQPACFLAA 790 800 810 820 830 840 LLNSQPLGFY SPSQLVQDAQ RHGVGVRPVD VTRSDWDCTL EPAKSTKLLG SDPNSGAAQL 850 860 870 880 890 900 PDVCRSPFVR LGLRQVSGLS ESAAQRIVAA RVEAPFTSTE DLALRCALEA GDLKALASAD 910 920 930 940 950 960 ALASLSGHRR QQVWDAAAQQ NAPGLLRAVP VAEAALQLPA ASEGEEVIFD YAALGLTLRS 970 980 990 1000 1010 1020 HPLLLLREQL SKMRLMTAAQ LRDLPNGRLA RACGIVTMRQ QPQTAKGVIF VTLEDETGQV 1030 1040 1050 1060 1070 1080 NVIVWKSLKE RQRPALLRSR LLAVYGTWQR DVESGGDVCH LIAGHLQDLT PLLGGLTTQS REFC

References

[1]

"Complete sequence of chromosome of Rhodoferax ferrireducens DSM 15236." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. , Kyrpides N., Ivanova N., Richardson P. Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000267 Genomic DNA. Translation: ABD68961.1.
RefSeq	YP_522492.1. NC_007908.1.
3D structure databases
ProteinModelPortal	Q21Z42.
ModBase	Search...
Protein-protein interaction databases
STRING	Q21Z42.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3961217.
GenomeReviews	Gene locus Rfer_1227 in contig CP000267_GR.
KEGG	rfr:Rfer_1227.
NMPDR	fig|338969.3.peg.3273.
PATRIC	23235009. VBIRhoFer131161_1529.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	EQPAIRL.
ProtClustDB	CLSK754011.
Enzyme and pathway databases
BioCyc	RFER338969:RFER_1227-MONOMER.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q21Z42_RHOFD

Accession

Primary (citable) accession number: Q21Z42

Entry history

Integrated into UniProtKB/TrEMBL:	April 18, 2006
Last sequence update:	April 18, 2006
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)