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Q21Y76 (Q21Y76_RHOFD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Rfer_1545
OrganismRhodoferax ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118) [Complete proteome] [HAMAP]
Taxonomic identifier338969 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Albidiferax

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2151Iron By similarity HAMAP MF_00323
Metal binding2961Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
Q21Y76 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: 809239420A6468E2

FASTA36941,285
        10         20         30         40         50         60 
MSFFKLSPFA PEPPFRHGQV PRTAVLYCNL GTPDTPTTPD VRRFLSEFLS DPRVVEIPRL 

        70         80         90        100        110        120 
LWLLILHGII LRVRPAKSAA KYASVWLPEG SPLKVWTEKQ AKLLQGWLAQ RGHQVQVRYA 

       130        140        150        160        170        180 
MRYGSTSIAE QLDALKAAGT TRVLILPAYP QYSATTTASL FDAVYAWAGQ VRAIPELRFV 

       190        200        210        220        230        240 
NHYHDDARYI AALTMSIQRH WKSHGRPDQL VMSFHGVPER TLQLGDPYHC ECRKTARLLA 

       250        260        270        280        290        300 
EQLGLSQEQF KVTYQSRLGR ARWLQPYTEP SLIAMGKAGV KRVDVVCPAF TSDCLETLEE 

       310        320        330        340        350        360 
INMEGRAAFL QAGGKEFHFI PCLNDDPEWI TALCDITQQH LAGWPTQAAP DAPQLAASRA 


AALALGAKQ

« Hide

References

[1]"Complete sequence of chromosome of Rhodoferax ferrireducens DSM 15236."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. expand/collapse author list , Kyrpides N., Ivanova N., Richardson P.
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000267 Genomic DNA. Translation: ABD69277.1.
RefSeqYP_522808.1. NC_007908.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ21Y76.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3960534.
GenomeReviewsGene locus Rfer_1545 in contig CP000267_GR.
KEGGrfr:Rfer_1545.
NMPDRfig|338969.3.peg.3085.
PATRIC23235677. VBIRhoFer131161_1856.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
PhylomeDBQ21Y76.
ProtClustDBCLSK951224.

Enzyme and pathway databases

BioCycRFER338969:RFER_1545-MONOMER.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ21Y76_RHOFD
AccessionPrimary (citable) accession number: Q21Y76
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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