Q21WW5 (GLMM_RHOFD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Rfer_2013

Organism

Rhodoferax ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118) [Complete proteome] [HAMAP]

Taxonomic identifier

338969 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Albidiferax

Protein attributes

Sequence length	443 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 443	443	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000301367
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q21WW5 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 70386823035485B4	FASTA	443	47,361
	10 20 30 40 50 60 MTRKYFGTDG IRGTVGQAPI TPDFVLRLAH AVGRVLKKSE ARPTVLIGKD TRISGYMLES 70 80 90 100 110 120 ALESGFNSAG VDVVLLGPLP TPGVAYLTRA QRASLGVVIS ASHNPFADNG IKFFSAQGSK 130 140 150 160 170 180 LPDVWEHDVE AALDEPPVWA DSASLGKTRR LDDAAGRYIE FCKSTFANDL TLKGLKIVVD 190 200 210 220 230 240 AAHGAAYQVA PKVFHELGAE VVAIGCSPDG LNINHEVGAT HPQALIEAVK AHQADFGVAL 250 260 270 280 290 300 DGDADRLQLV DHAGRLYNGD ELLYLLVDER LGRDEPVPGV VGTLMTNMAV EVALRARGVQ 310 320 330 340 350 360 FVRAKVGDRY VLEELEKHKW LLGGEGSGHL LALDKHTTGD GLISALQVLQ ACVRSGKKLA 370 380 390 400 410 420 ELLAEVTLFP QTLINVRLQP GQDWQVSANL ASESRAVETE LGAAGRLLIR ASGTEPLVRV 430 440 MVEARDAVQA RACAERIANT LSV

References

[1]

"Complete sequence of chromosome of Rhodoferax ferrireducens DSM 15236." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. , Kyrpides N., Ivanova N., Richardson P. Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 15236 / ATCC BAA-621 / T118.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000267 Genomic DNA. Translation: ABD69738.1.
RefSeq	YP_523269.1. NC_007908.1.
3D structure databases
ProteinModelPortal	Q21WW5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q21WW5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3961761.
GenomeReviews	Gene locus Rfer_2013 in contig CP000267_GR.
KEGG	rfr:Rfer_2013.
NMPDR	fig|338969.3.peg.1908.
PATRIC	23236671. VBIRhoFer131161_2345.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	ESTDNIM.
PhylomeDB	Q21WW5.
ProtClustDB	PRK10887.
Enzyme and pathway databases
BioCyc	RFER338969:RFER_2013-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_RHOFD

Accession

Primary (citable) accession number: Q21WW5

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	April 18, 2006
Last modified:	January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program