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Q21WC7 (Q21WC7_RHOFD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 1 HAMAP MF_00163
Short name=PDF 1 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 1 HAMAP MF_00163
Gene names
Name:def1 HAMAP MF_00163
Ordered Locus Names:Rfer_2202
OrganismRhodoferax ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118) [Complete proteome] [HAMAP]
Taxonomic identifier338969 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Albidiferax

Protein attributes

Sequence length186 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1511 By similarity HAMAP MF_00163
Metal binding1081Iron By similarity HAMAP MF_00163
Metal binding1501Iron By similarity HAMAP MF_00163
Metal binding1541Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
Q21WC7 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: 5808BB936C829A4D

FASTA18620,618
        10         20         30         40         50         60 
MAIREILKMG DPRLLRIAPP VTLFDTDELH LLISDMLDTM LAADGAGLAA PQIGVDLQLV 

        70         80         90        100        110        120 
IFGSNARNPR YPQAPVVPQT VLLNPVITPL PPSENDATPL QVEDWEGCLS VPGLRAMVPR 

       130        140        150        160        170        180 
FARIRYTGFD QYGDPINRTV EGFHARVVQH ECDHLIGKLY PMRVRDFSRF GFTDVLFPGL 


DAGQDD

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References

[1]"Complete sequence of chromosome of Rhodoferax ferrireducens DSM 15236."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. expand/collapse author list , Kyrpides N., Ivanova N., Richardson P.
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000267 Genomic DNA. Translation: ABD69926.1.
RefSeqYP_523457.1. NC_007908.1.

3D structure databases

ProteinModelPortalQ21WC7.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ21WC7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3963149.
GenomeReviewsGene locus Rfer_2202 in contig CP000267_GR.
KEGGrfr:Rfer_2202.
NMPDRfig|338969.3.peg.3852.
PATRIC23237071. VBIRhoFer131161_2543.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0242.
HOGENOMHBG665227.
OMARYPEAPS.

Enzyme and pathway databases

BioCycRFER338969:RFER_2202-MONOMER.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ21WC7_RHOFD
AccessionPrimary (citable) accession number: Q21WC7
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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