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Q21W90

- TYPH_ALBFT

UniProt

Q21W90 - TYPH_ALBFT

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Protein
Putative thymidine phosphorylase
Gene
Rfer_2241
Organism
Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Rhodoferax ferrireducens)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. phosphorylase activity Source: InterPro
  2. thymidine phosphorylase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. pyrimidine nucleobase metabolic process Source: InterPro
  2. pyrimidine nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciAFER338969:GHU9-2263-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylase (EC:2.4.2.4)
Alternative name(s):
TdRPase
Gene namesi
Ordered Locus Names:Rfer_2241
OrganismiAlbidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Rhodoferax ferrireducens)
Taxonomic identifieri338969 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeRhodoferax
ProteomesiUP000008332: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 522522Putative thymidine phosphorylaseUniRule annotation
PRO_0000314712Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi338969.Rfer_2241.

Structurei

3D structure databases

ProteinModelPortaliQ21W90.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiCLIWGGH.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q21W90-1 [UniParc]FASTAAdd to Basket

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MRKHTDKPQL ASKLVLRRVA IDTYRENVAY LHRDCAVYRA EGFQALSKVE    50
VRANGRHILA TLNVVDDPNI VACNELGLSE DAFAQMAVID GQPASVSQAE 100
PPQSIGALRR KLAGERLGRE DFLGIVRDIA ELHYSKIELS AFVVATNRDE 150
LDREEVYFLT EAMVASGRTL NWHEPLVVDK HCIGGIPGNR SSMLVVPIVA 200
AHGLLCPKTS SRAITSPAGT ADTMEVLAKV ELPVDQLADI VRTHRGCLAW 250
GGAAHLSPAD DVLISVERPL AIDSPGQMVA SILSKKIAAG STHLVLDIPI 300
GPSAKVRSMP EAQRLRRLFE YVAGRMHLSL DVVVTDGRQP IGNGIGPVLE 350
ARDVMRVLEN DPRAPNDLRQ KSLRLAGRLI EFDPDVRGGD GFAIARDILD 400
SGRALAKMNA IIAAQGAKPF DHNHPQLGAL TFDICASESG VVTGIDNLQV 450
ARIARLAGAP KVIGAGIDLF HKLGEAVTSG EVLYRVHAGF QSDLDFARQA 500
CAKSTGYTLG RAEDVPHVFT EF 522
Length:522
Mass (Da):56,346
Last modified:April 18, 2006 - v1
Checksum:i713D9EC0997E943B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000267 Genomic DNA. Translation: ABD69963.1.
RefSeqiYP_523494.1. NC_007908.1.

Genome annotation databases

EnsemblBacteriaiABD69963; ABD69963; Rfer_2241.
GeneIDi3962042.
KEGGirfr:Rfer_2241.
PATRICi23237155. VBIRhoFer131161_2585.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000267 Genomic DNA. Translation: ABD69963.1 .
RefSeqi YP_523494.1. NC_007908.1.

3D structure databases

ProteinModelPortali Q21W90.
ModBasei Search...

Protein-protein interaction databases

STRINGi 338969.Rfer_2241.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABD69963 ; ABD69963 ; Rfer_2241 .
GeneIDi 3962042.
KEGGi rfr:Rfer_2241.
PATRICi 23237155. VBIRhoFer131161_2585.

Phylogenomic databases

eggNOGi COG0213.
HOGENOMi HOG000252767.
KOi K00758.
OMAi CLIWGGH.
OrthoDBi EOG61ZTGG.

Enzyme and pathway databases

BioCyci AFER338969:GHU9-2263-MONOMER.

Family and domain databases

Gene3Di 3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPi MF_00703. Thymid_phosp_2.
InterProi IPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view ]
PANTHERi PTHR10515. PTHR10515. 1 hit.
Pfami PF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF000478. TP_PyNP. 1 hit.
SMARTi SM00941. PYNP_C. 1 hit.
[Graphical view ]
SUPFAMi SSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsi TIGR02645. ARCH_P_rylase. 1 hit.
PROSITEi PS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Rhodoferax ferrireducens DSM 15236."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.
    , Kyrpides N., Ivanova N., Richardson P.
    Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-621 / DSM 15236 / T118.

Entry informationi

Entry nameiTYPH_ALBFT
AccessioniPrimary (citable) accession number: Q21W90
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 18, 2006
Last modified: June 11, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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