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Protein

Aspartate/glutamate leucyltransferase

Gene

bpt

Organism
Rhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Albidiferax ferrireducens)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-glutamyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-glutamyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-aspartyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-aspartyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate/glutamate leucyltransferaseUniRule annotation (EC:2.3.2.29UniRule annotation)
Gene namesi
Name:bptUniRule annotation
Ordered Locus Names:Rfer_2348
OrganismiRhodoferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Albidiferax ferrireducens)
Taxonomic identifieri338969 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeRhodoferax
Proteomesi
  • UP000008332 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002632101 – 253Aspartate/glutamate leucyltransferaseAdd BLAST253

Interactioni

Protein-protein interaction databases

STRINGi338969.Rfer_2348

Family & Domainsi

Sequence similaritiesi

Belongs to the R-transferase family. Bpt subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWA Bacteria
COG2935 LUCA
HOGENOMiHOG000003225
KOiK21420
OMAiWQIEQAR
OrthoDBiPOG091H04D7

Family and domain databases

HAMAPiMF_00689 Bpt, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR017138 Asp_Glu_LeuTrfase
IPR030700 N-end_Aminoacyl_Trfase
IPR007472 N-end_Aminoacyl_Trfase_C
IPR007471 N-end_Aminoacyl_Trfase_N
PANTHERiPTHR21367 PTHR21367, 2 hits
PfamiView protein in Pfam
PF04377 ATE_C, 1 hit
PF04376 ATE_N, 1 hit
PIRSFiPIRSF037208 ATE_pro_prd, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit

Sequencei

Sequence statusi: Complete.

Q21VY8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLKELPLNA LQFYATSSYP CSYLPGQQAR SQVAAPSHLV NGVIYAELVR
60 70 80 90 100
QGFRRSGLFT YRPYCDGCCA CTPVRVLVAE FQPDRSQRRA WSRHSTLQAR
110 120 130 140 150
VLKPSFVQEH YDLYLRYQNT RHAGGGMDHD SVDQYTQFLL QSRVNSRLIE
160 170 180 190 200
FRETLADGEP GPLKLVSILD VLDDGLSAVY TFYEPESSGS LGTYGVLWQI
210 220 230 240 250
AEAKKLGLAY VYLGFWIKDS QKMNYKTRFR PLEFLVSGNW RADYPSMPAS

QLS
Length:253
Mass (Da):28,808
Last modified:April 18, 2006 - v1
Checksum:i8A368A6C4C5EC9BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000267 Genomic DNA Translation: ABD70065.1

Genome annotation databases

EnsemblBacteriaiABD70065; ABD70065; Rfer_2348
KEGGirfr:Rfer_2348

Similar proteinsi

Entry informationi

Entry nameiBPT_RHOFT
AccessioniPrimary (citable) accession number: Q21VY8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: April 18, 2006
Last modified: April 25, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health