Q21U08PANC_ALBFTPantothenate synthetasePS6.3.2.1Pantoate--beta-alanine ligasePantoate-activating enzymepanCRfer_3034Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118)Rhodoferax ferrireducensBacteriaPseudomonadotaBetaproteobacteriaBurkholderialesComamonadaceaeRhodoferaxComplete sequence of chromosome of Rhodoferax ferrireducens DSM 15236.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.Homodimer.CytoplasmThe reaction proceeds by a bi uni uni bi ping pong mechanism.Belongs to the pantothenate synthetase family.ATP-bindingCytoplasmLigaseNucleotide-bindingPantothenate biosynthesisReference proteomeATP(R)-pantoatebeta-alanineATP(R)-pantoateATPATPMKIVRTIAELRQHLSAYKHPAFVPTMGNLHEGHLSLLRQAKPLGDVLVASIFVNRLQFLPHEDFDTYPRTWEADCQALQAAGCDVLFAPGEQELYPEPQTYRVQPPAELADILEGHFRPGFFVGVSTVVMKLFACVQPRVAVFGQKDYQQLMVIRGMVRQFALPIAVLGVATLRAADGLALSSRNNYLTPLERAEAVHLSQSLQQMAKALRAGTVDIAALEQQAMVDLTARGWQPDYLAARRRADLQVPAADEVAALVQNDGLVLLGAARIGNTRLIDNLEV
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