Q21SZ4 (URE2_RHOFD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease subunit beta
EC=3.5.1.5

Alternative name(s):
Urea amidohydrolase subunit beta

Gene names

Name:	ureB
Ordered Locus Names:	Rfer_3400

Organism

Rhodoferax ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118) [Complete proteome] [HAMAP]

Taxonomic identifier

338969 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Albidiferax › Albidiferax ferrireducens

Protein attributes

Sequence length	101 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Urea + H2O = CO2 + 2 NH3. HAMAP-Rule MF_01954
Pathway	Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. HAMAP-Rule MF_01954
Subunit structure	Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme By similarity.
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_01954.
Sequence similarities	Belongs to the urease beta subunit family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	urea catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	urease activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 101	101	Urease subunit beta HAMAP-Rule MF_01954		PRO_0000239897

Sequences

	Sequence		Length	Mass (Da)
	Q21SZ4 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 17CF0ECA63F0C561	FASTA	101	10,829
	10 20 30 40 50 60 MIPGELFTDG PEHVLNPGRR AHTLAVVNAS DRPIQVGSHY HFAETNGALG FDRAAAKGMR 70 80 90 100 LNIASGSAVR LEPGQQRTVE LVDYAGDRIV YGFRGLTQGA L

References

[1]

"Complete sequence of chromosome of Rhodoferax ferrireducens DSM 15236." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M. , Kyrpides N., Ivanova N., Richardson P. Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 15236 / ATCC BAA-621 / T118.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000267 Genomic DNA. Translation: ABD71109.1.
RefSeq	YP_524640.1. NC_007908.1.
3D structure databases
ProteinModelPortal	Q21SZ4.
SMR	Q21SZ4. Positions 1-101.
ModBase	Search...
Protein-protein interaction databases
STRING	338969.Rfer_3400.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABD71109; ABD71109; Rfer_3400.
GeneID	3962184.
KEGG	rfr:Rfer_3400.
PATRIC	23239583. VBIRhoFer131161_3786.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0832.
HOGENOM	HOG000077770.
KO	K01429.
OMA	REVYGFQ.
ProtClustDB	PRK13203.
Enzyme and pathway databases
BioCyc	AFER338969:GHU9-3442-MONOMER.
UniPathway	UPA00258; UER00370.
Family and domain databases
Gene3D	2.10.150.10. 1 hit.
HAMAP	MF_01954. Urease_beta.
InterPro	IPR002019. Urease_beta. [Graphical view]
Pfam	PF00699. Urease_beta. 1 hit. [Graphical view]
SUPFAM	SSF51278. Urease_beta. 1 hit.
TIGRFAMs	TIGR00192. urease_beta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

URE2_RHOFD

Accession

Primary (citable) accession number: Q21SZ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 13, 2006
Last sequence update:	April 18, 2006
Last modified:	May 29, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program