ID   RLMF_SACD2              Reviewed;         320 AA.
AC   Q21P11;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 1.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=Ribosomal RNA large subunit methyltransferase F;
DE            EC=2.1.1.48;
DE   AltName: Full=23S rRNA mA1618 methyltransferase;
DE   AltName: Full=rRNA adenine N-6-methyltransferase;
GN   Name=rlmF; OrderedLocusNames=Sde_0304;
OS   Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Saccharophagus.
OX   NCBI_TaxID=203122;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Saunders E.H., Brettin T., Bruce D.,
RA   Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P., Weiner R.;
RT   "Complete sequence of Saccharophagus degradans 2-40.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Specifically methylates the adenine in position 1618 of
CC       23S rRNA (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-
CC       homocysteine + rRNA containing N(6)-methyladenine.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       METT10D/rlmF family.
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DR   EMBL; CP000282; ABD79568.1; -; Genomic_DNA.
DR   RefSeq; YP_525780.1; -.
DR   GeneID; 3965443; -.
DR   GenomeReviews; CP000282_GR; Sde_0304.
DR   KEGG; sde:Sde_0304; -.
DR   NMPDR; fig|203122.1.peg.2392; -.
DR   HOGENOM; Q21P11; -.
DR   OMA; Q21P11; LNFGGQN.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008988; F:rRNA (adenine-N6-)-methyltransferase activity; IEA:HAMAP.
DR   GO; GO:0000154; P:rRNA modification; IEA:InterPro.
DR   HAMAP; MF_01848; -; 1.
DR   InterPro; IPR016909; S-AdoMet-dep_MeTrfase_YbiN_prd.
DR   InterPro; IPR010286; SAM-Mtase_prd.
DR   PANTHER; PTHR13393; DUF890; 1.
DR   Pfam; PF05971; Methyltransf_10; 1.
DR   PIRSF; PIRSF029038; Mtase_YbiN_prd; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methyltransferase; rRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    320       Ribosomal RNA large subunit
FT                                methyltransferase F.
FT                                /FTId=PRO_0000349944.
SQ   SEQUENCE   320 AA;  35321 MW;  9A349CF283A8FEC2 CRC64;
     MHKSANSKTR KQSKGLHPRN IHRNGYDFDA LKACHPPLVQ YIKCNPVGAA TIDFANSAAV
     KALNTALLQH HYKIESWSIP DGALCPPIPG RIDYIHYIAE LLGCPLPSGK INTANTCTNN
     AVKMLDVGTG ANGIYTLLAC AVYGWRCVGS DINSESLANV KAVLANNPTL NANISLRLQP
     NKDAFFSQII QTDDYFDVSV CNPPFHASQE EASKGTNRKL HNLARSRNKA HTAKQPSLNF
     GGQHAELWCN GGERLFLKKM IKESQAFAQQ VGWFTSLVSK SENVQPALKL IRKLGATEVR
     EIEMMQGNKK TRVIAWRFKP
//