Reviewed, UniProtKB/Swiss-Prot Q21P11 (RLMF_SACD2)

Names and origin

Protein names

Recommended name:
    Ribosomal RNA large subunit methyltransferase F
    EC=2.1.1.48
Alternative name(s):
    23S rRNA mA1618 methyltransferase
    rRNA adenine N-6-methyltransferase

Gene names

Name:	rlmF
Ordered Locus Names:	Sde_0304

Organism

Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) [Complete proteome] [HAMAP]

Taxonomic identifier

203122 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Saccharophagus

Protein attributes

Sequence length	320 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Specifically methylates the adenine in position 1618 of 23S rRNA By similarity.
Catalytic activity	S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine. HAMAP MF_01848
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the methyltransferase superfamily. METT10D/rlmF family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rRNA modification Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (adenine-N6-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 320	320	Ribosomal RNA large subunit methyltransferase F HAMAP MF_01848		PRO_0000349944

Sequences

	Sequence		Length	Mass (Da)
	Q21P11-1 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 9A349CF283A8FEC2	FASTA	320	35,321
	10 20 30 40 50 60 MHKSANSKTR KQSKGLHPRN IHRNGYDFDA LKACHPPLVQ YIKCNPVGAA TIDFANSAAV 70 80 90 100 110 120 KALNTALLQH HYKIESWSIP DGALCPPIPG RIDYIHYIAE LLGCPLPSGK INTANTCTNN 130 140 150 160 170 180 AVKMLDVGTG ANGIYTLLAC AVYGWRCVGS DINSESLANV KAVLANNPTL NANISLRLQP 190 200 210 220 230 240 NKDAFFSQII QTDDYFDVSV CNPPFHASQE EASKGTNRKL HNLARSRNKA HTAKQPSLNF 250 260 270 280 290 300 GGQHAELWCN GGERLFLKKM IKESQAFAQQ VGWFTSLVSK SENVQPALKL IRKLGATEVR 310 320 EIEMMQGNKK TRVIAWRFKP

References

[1]

"Complete sequence of Saccharophagus degradans 2-40." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Kyrpides N., Lykidis A., Richardson P., Weiner R. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000282 Genomic DNA. Translation: ABD79568.1.
RefSeq	YP_525780.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3965443.
GenomeReviews	Gene locus Sde_0304 in contig CP000282_GR.
KEGG	sde:Sde_0304.
NMPDR	fig|203122.1.peg.2392.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q21P11.
OMA	Q21P11. LNFGGQN.
Family and domain databases
HAMAP	MF_01848. [Tree]
InterPro	IPR016909. S-AdoMet-dep_MeTrfase_YbiN_prd. IPR010286. SAM-Mtase_prd. [Graphical view]
PANTHER	PTHR13393. DUF890. 1 hit.
Pfam	PF05971. Methyltransf_10. 1 hit. [Graphical view]
PIRSF	PIRSF029038. Mtase_YbiN_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMF_SACD2

Accession

Primary (citable) accession number: Q21P11

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	April 18, 2006
Last modified:	June 16, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)