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Protein

Acetylornithine deacetylase

Gene

Sde_0363

Organism
Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

N2-acetyl-L-ornithine + H2O = acetate + L-ornithine.SAAS annotation

Cofactori

Protein has several cofactor binding sites:
  • Co2+SAAS annotation
  • Zn2+SAAS annotation
  • glutathioneSAAS annotation

Pathwayi: L-arginine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes L-ornithine from N(2)-acetyl-L-ornithine (linear).SAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Acetylornithine deacetylase (Sde_0363)
This subpathway is part of the pathway L-arginine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-ornithine from N(2)-acetyl-L-ornithine (linear), the pathway L-arginine biosynthesis and in Amino-acid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseSAAS annotationImported
Biological processAmino-acid biosynthesis, Arginine biosynthesisSAAS annotation
LigandCobaltSAAS annotation, Metal-bindingSAAS annotation, ZincSAAS annotation

Enzyme and pathway databases

BioCyciSDEG203122:G1G67-382-MONOMER
UniPathwayiUPA00068; UER00110

Protein family/group databases

MEROPSiM20.974

Names & Taxonomyi

Protein namesi
Recommended name:
Acetylornithine deacetylaseSAAS annotation (EC:3.5.1.16SAAS annotation)
Gene namesi
Ordered Locus Names:Sde_0363Imported
OrganismiSaccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)Imported
Taxonomic identifieri203122 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCellvibrionalesCellvibrionaceaeSaccharophagus
Proteomesi
  • UP000001947 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Interactioni

Subunit structurei

Homodimer.SAAS annotation

Protein-protein interaction databases

STRINGi203122.Sde_0363

Structurei

3D structure databases

ProteinModelPortaliQ21NV2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini182 – 291M20_dimerInterPro annotationAdd BLAST110

Sequence similaritiesi

Belongs to the peptidase M20A family. ArgE subfamily.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105CWC Bacteria
COG0624 LUCA
HOGENOMiHOG000243769
KOiK01438
OMAiCAHQPGE
OrthoDBiPOG091H0GAZ

Family and domain databases

CDDicd03894 M20_ArgE, 1 hit
InterProiView protein in InterPro
IPR010169 AcOrn-deacetyl
IPR036264 Bact_exopeptidase_dim_dom
IPR002933 Peptidase_M20
IPR011650 Peptidase_M20_dimer
PANTHERiPTHR43808:SF1 PTHR43808:SF1, 1 hit
PfamiView protein in Pfam
PF07687 M20_dimer, 1 hit
PF01546 Peptidase_M20, 1 hit
SUPFAMiSSF55031 SSF55031, 1 hit
TIGRFAMsiTIGR01892 AcOrn-deacetyl, 1 hit

Sequencei

Sequence statusi: Complete.

Q21NV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPNIAPSDVT VFKQRLQQLI ATPSISCTSA EYDMSNKSVV ELLAQWFEDL
60 70 80 90 100
GFKIEILPVE GFAGKYNLLA TRGTGPGGLV LSGHTDTVPC DPNRWQQDPF
110 120 130 140 150
QLTEKEQRFY GLGTTDMKGF FPVVLAALEG LDLNKLQQPV MILATADEES
160 170 180 190 200
SMCGARALAA LGRPKARCAV IGEPTELKPI RMHKGIMMES VRVQGLAGHS
210 220 230 240 250
SNPALGHNAL DTMTQVLNEL ILFRSELQSR YQHAGFDINV PTLNLGCIHG
260 270 280 290 300
GDNPNRICGA CELHFDLRAL PGMSNHDLHA EIEKRLQAIG DKNHTPISLT
310 320 330 340 350
PLFPGIASFE EQADSALVKA AERLSGYQAE SVAFATEAPF LQDLGMETIV
360 370 380
MGPGTIDCAH QPNEYLAHDQ IQPGINIVRG LIEQFCF
Length:387
Mass (Da):42,190
Last modified:April 18, 2006 - v1
Checksum:i36971E0EAD6025BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000282 Genomic DNA Translation: ABD79627.1
RefSeqiWP_011466851.1, NC_007912.1

Genome annotation databases

EnsemblBacteriaiABD79627; ABD79627; Sde_0363
KEGGisde:Sde_0363

Similar proteinsi

Entry informationi

Entry nameiQ21NV2_SACD2
AccessioniPrimary (citable) accession number: Q21NV2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: March 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health