ID   APAH_SACD2              Reviewed;         271 AA.
AC   Q21MT2;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 1.
DT   16-JUN-2009, entry version 18.
DE   RecName: Full=Bis(5'-nucleosyl)-tetraphosphatase, symmetrical;
DE            EC=3.6.1.41;
DE   AltName: Full=Diadenosine tetraphosphatase;
DE   AltName: Full=Ap4A hydrolase;
DE   AltName: Full=Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase;
GN   Name=apaH; OrderedLocusNames=Sde_0735;
OS   Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Saccharophagus.
OX   NCBI_TaxID=203122;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Saunders E.H., Brettin T., Bruce D.,
RA   Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P., Weiner R.;
RT   "Complete sequence of Saccharophagus degradans 2-40.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to
CC       yield ADP (By similarity).
CC   -!- CATALYTIC ACTIVITY: P(1),P(4)-bis(5'-adenosyl) tetraphosphate +
CC       H(2)O = 2 ADP.
CC   -!- SIMILARITY: Belongs to the Ap4A hydrolase family.
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DR   EMBL; CP000282; ABD79997.1; -; Genomic_DNA.
DR   RefSeq; YP_526209.1; -.
DR   GeneID; 3966256; -.
DR   GenomeReviews; CP000282_GR; Sde_0735.
DR   KEGG; sde:Sde_0735; -.
DR   NMPDR; fig|203122.1.peg.4323; -.
DR   HOGENOM; Q21MT2; -.
DR   OMA; Q21MT2; LVFGHWA.
DR   BioCyc; SDEG203122:SDE_0735-MON; -.
DR   GO; GO:0008803; F:bis(5'-nucleosyl)-tetraphosphatase (symmetr...; IEA:HAMAP.
DR   HAMAP; MF_00199; -; 1.
DR   InterPro; IPR004617; ApaH.
DR   InterPro; IPR004843; M-pesterase.
DR   Pfam; PF00149; Metallophos; 1.
DR   PIRSF; PIRSF000903; B5n-ttraPtase_sm; 1.
DR   TIGRFAMs; TIGR00668; apaH; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    271       Bis(5'-nucleosyl)-tetraphosphatase,
FT                                symmetrical.
FT                                /FTId=PRO_1000012085.
SQ   SEQUENCE   271 AA;  30183 MW;  B4026CC8271AC00B CRC64;
     MATYAVGDIQ GCYRALKLLL KKVKFNADND HLWVAGDLVN RGPESLKSLR YIKKLGPSAT
     LVLGNHDLHL LAHAYGVRTL NPKDTLAPIL TAKDSDELLE WLQAQPLLHY DAEFDAVLVH
     AGIPPIWSIE NALNYALEVE QALSTTQTAA AFFVDMYGNQ PDVWQPSLEG TARLRLITNY
     LTRMRFCSPT GKLELQTKNA PSLPPTGFAP WYTHKHNKWG NTKILFGHWA ALMGETRSKQ
     FIGLDTGCVW GGALTMMRLE DGQFFAVDCP C
//