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Q21MC3

- PUR5_SACD2

UniProt

Q21MC3 - PUR5_SACD2

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSDEG203122:GI2M-900-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
Alternative name(s):
AIR synthaseUniRule annotation
AIRSUniRule annotation
Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
Gene namesi
Name:purMUniRule annotation
Ordered Locus Names:Sde_0894
OrganismiSaccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Taxonomic identifieri203122 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeSaccharophagus
ProteomesiUP000001947: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 352352Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000258399Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi203122.Sde_0894.

Structurei

3D structure databases

ProteinModelPortaliQ21MC3.
SMRiQ21MC3. Positions 12-347.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229091.
KOiK01933.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741. AIRS.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q21MC3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTDSKSNSNS PSLSYKDAGV DIDAGNALVE RIKSVAKRTR RPEVMAGLGG
60 70 80 90 100
FGALFELPKG YQEPVLVAGT DGVGTKLKLA MQLNKHDTIG IDLVAMCVND
110 120 130 140 150
LIVGGAEPLF FLDYYATGKL SVDVAASVVE GIGAGCELSG CSLVGGETAE
160 170 180 190 200
MPGMYEGEDY DLAGFCVGIV EKSKILDGSK VAAGDVLLGI PSSGPHSNGY
210 220 230 240 250
SLIRKVLEVS GASLDDKVGD TTLGQALLEP TRIYVKPLLE LFKNVQVNAL
260 270 280 290 300
SHITGGGLLE NIPRVLPENT RAQIDCASWE LPPVFKWLQE QGNINAVEMY
310 320 330 340 350
RTFNCGVGMI VCVPAAEAAN AIAQLKQSGE DAFEIGKIVA AEGAPEVDLL

NL
Length:352
Mass (Da):36,976
Last modified:October 31, 2006 - v2
Checksum:i874DA43356064372
GO

Sequence cautioni

The sequence ABD80156.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000282 Genomic DNA. Translation: ABD80156.1. Different initiation.
RefSeqiYP_526368.1. NC_007912.1.

Genome annotation databases

EnsemblBacteriaiABD80156; ABD80156; Sde_0894.
GeneIDi3965491.
KEGGisde:Sde_0894.
PATRICi23400553. VBISacDeg56404_0980.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000282 Genomic DNA. Translation: ABD80156.1 . Different initiation.
RefSeqi YP_526368.1. NC_007912.1.

3D structure databases

ProteinModelPortali Q21MC3.
SMRi Q21MC3. Positions 12-347.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 203122.Sde_0894.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABD80156 ; ABD80156 ; Sde_0894 .
GeneIDi 3965491.
KEGGi sde:Sde_0894.
PATRICi 23400553. VBISacDeg56404_0980.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229091.
KOi K01933.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci SDEG203122:GI2M-900-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741. AIRS.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 2-40 / ATCC 43961 / DSM 17024.

Entry informationi

Entry nameiPUR5_SACD2
AccessioniPrimary (citable) accession number: Q21MC3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: October 29, 2014
This is version 59 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3