ID   Q21LJ4_SACD2            Unreviewed;       460 AA.
AC   Q21LJ4;
DT   18-APR-2006, integrated into UniProtKB/TrEMBL.
DT   18-APR-2006, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Adenylyl cyclase class-3/4/guanylyl cyclase {ECO:0000313|EMBL:ABD80435.1};
GN   OrderedLocusNames=Sde_1173 {ECO:0000313|EMBL:ABD80435.1};
OS   Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC   Cellvibrionaceae; Saccharophagus.
OX   NCBI_TaxID=203122 {ECO:0000313|EMBL:ABD80435.1, ECO:0000313|Proteomes:UP000001947};
RN   [1] {ECO:0000313|EMBL:ABD80435.1, ECO:0000313|Proteomes:UP000001947}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2-40 / ATCC 43961 / DSM 17024
RC   {ECO:0000313|Proteomes:UP000001947};
RX   PubMed=18516288; DOI=10.1371/journal.pgen.1000087;
RA   Weiner R.M., Taylor L.E.II., Henrissat B., Hauser L., Land M.,
RA   Coutinho P.M., Rancurel C., Saunders E.H., Longmire A.G., Zhang H.,
RA   Bayer E.A., Gilbert H.J., Larimer F., Zhulin I.B., Ekborg N.A., Lamed R.,
RA   Richardson P.M., Borovok I., Hutcheson S.;
RT   "Complete genome sequence of the complex carbohydrate-degrading marine
RT   bacterium, Saccharophagus degradans strain 2-40 T.";
RL   PLoS Genet. 4:E1000087-E1000087(2008).
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DR   EMBL; CP000282; ABD80435.1; -; Genomic_DNA.
DR   RefSeq; WP_011467655.1; NC_007912.1.
DR   AlphaFoldDB; Q21LJ4; -.
DR   STRING; 203122.Sde_1173; -.
DR   KEGG; sde:Sde_1173; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_047397_0_0_6; -.
DR   OrthoDB; 9806704at2; -.
DR   Proteomes; UP000001947; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001947};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        44..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        121..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        151..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          226..361
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   460 AA;  51897 MW;  79C7A0FB918C5A7F CRC64;
     MSDSKQADPN IEYSLRQNDI RALICCAAAG TLLVNVSWSS LFVIESLVAM SVLSYALGSY
     LWLKQISHGP RAATLFDRVM TMDAAVIGLV VSFSGFNILP TILFITMIQF NSLINGGVKK
     WAIDNVAFFV GVGFTFLIRE PQLVFSDKLE ISAVSLIGIF TYFCAYALYA HNRIHKLELS
     NKKLVNEQTL YKLRTYKLAR YLTPTVWKAV NEGREKDLST ERKRVTVFFS DIMGFSALSE
     ELEAETLTDI LNTYLTEMTK IATKHKGTID KFMGDGVMIV FGDNESAGVK TDCLRCVAMS
     IEMRRKMKEL QTKWYNQGIK KPLQIRMGIN TGYCTVGSFG TNHYMDYTVL GTHVNLASRL
     ESAASPGEIL VSHETWALIK DVVMCRDKGE ISAKGFSHAI KVYEVADFRK DLGKQQSYFE
     HNSEGFSMHL DLDKIRNYDK DKVITYLERA ADKLRDKIIS
//