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Q21L94 (UXUA_SACD2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannonate dehydratase
EC=4.2.1.8
Alternative name(s):
D-mannonate hydrolase
Gene names
Name:uxuA
Ordered Locus Names:Sde_1273
OrganismSaccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) [Complete proteome] [HAMAP]
Taxonomic identifier203122 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Saccharophagus

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106

Sequence similarities

Belongs to the mannonate dehydratase family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionmannonate dehydratase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Mannonate dehydratase HAMAP MF_00106
PRO_1000034336

Sequences

Sequence LengthMass (Da)Tools
Q21L94 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: DE00F0445A7A00A7

FASTA39744,372
        10         20         30         40         50         60 
MQETWRWFGP NDSISLQKIA QAGATGIVSS LHHVPTGALW QLEEIEAQKK IIEDAGLEWS 

        70         80         90        100        110        120 
VIESIPVHND IKTRTGNFQE YIENYKQSVI NAGKAGVKTI CYNFMPVVDW TRTNLSYRLP 

       130        140        150        160        170        180 
NASQALRFEM TDFAAYDVYL LQRENAAADY SEEVLNRAKA RFDAMDETEK DLLEKNIIAG 

       190        200        210        220        230        240 
LPGGEGSYTR DTIREAIQQF IDLGTEGFRN HMFEFLREII PAAESVGVKM CIHPDDPPFS 

       250        260        270        280        290        300 
LFGLPRVVST ADDARKLLNA VPSPSNGLTL CAGSYGARGD NDLVGMAKEF GDRIYFVHLR 

       310        320        330        340        350        360 
NVKREPDGSF YEADHLDGDN DMVGLVNALL CEERRRHAAG ETNCAIPMRP DHGHLMADEL 

       370        380        390 
NLPDVKPGYS YTGRMKGLAE LRGVIHALEV LQRQHAL

« Hide

References

[1]"Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 T."
Weiner R.M., Taylor L.E. II, Henrissat B., Hauser L., Land M., Coutinho P.M., Rancurel C., Saunders E.H., Longmire A.G., Zhang H., Bayer E.A., Gilbert H.J., Larimer F., Zhulin I.B., Ekborg N.A., Lamed R., Richardson P.M., Borovok I., Hutcheson S.
PLoS Genet. 4:E1000087-E1000087(2008) [PubMed: 18516288] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2-40 / ATCC 43961 / DSM 17024.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000282 Genomic DNA. Translation: ABD80535.1.
RefSeqYP_526747.1. NC_007912.1.

3D structure databases

ProteinModelPortalQ21L94.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ21L94.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3965255.
GenomeReviewsGene locus Sde_1273 in contig CP000282_GR.
KEGGsde:Sde_1273.
NMPDRfig|203122.1.peg.3541.
PATRIC23401405. VBISacDeg56404_1394.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1312.
HOGENOMHBG585927.
OMARPDHGHL.
PhylomeDBQ21L94.
ProtClustDBPRK03906.

Enzyme and pathway databases

BioCycSDEG203122:SDE_1273-MONOMER.

Family and domain databases

HAMAPMF_00106. UxuA.
[Tree]
InterProIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01686.
PfamPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFPIRSF016049. Man_dehyd. 1 hit.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR00695. UxuA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUXUA_SACD2
AccessionPrimary (citable) accession number: Q21L94
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 18, 2006
Last modified: January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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