Reviewed, UniProtKB/Swiss-Prot Q21L94 (UXUA_SACD2)

Names and origin

Protein names

Recommended name:
    Mannonate dehydratase
    EC=4.2.1.8
Alternative name(s):
    D-mannonate hydrolase

Gene names

Name:	uxuA
Ordered Locus Names:	Sde_1273

Organism

Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) [Complete proteome] [HAMAP]

Taxonomic identifier

203122 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Saccharophagus

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106
Sequence similarities	Belongs to the mannonate dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannonate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Mannonate dehydratase HAMAP MF_00106		PRO_1000034336

Sequences

	Sequence		Length	Mass (Da)
	Q21L94-1 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: DE00F0445A7A00A7	FASTA	397	44,372
	10 20 30 40 50 60 MQETWRWFGP NDSISLQKIA QAGATGIVSS LHHVPTGALW QLEEIEAQKK IIEDAGLEWS 70 80 90 100 110 120 VIESIPVHND IKTRTGNFQE YIENYKQSVI NAGKAGVKTI CYNFMPVVDW TRTNLSYRLP 130 140 150 160 170 180 NASQALRFEM TDFAAYDVYL LQRENAAADY SEEVLNRAKA RFDAMDETEK DLLEKNIIAG 190 200 210 220 230 240 LPGGEGSYTR DTIREAIQQF IDLGTEGFRN HMFEFLREII PAAESVGVKM CIHPDDPPFS 250 260 270 280 290 300 LFGLPRVVST ADDARKLLNA VPSPSNGLTL CAGSYGARGD NDLVGMAKEF GDRIYFVHLR 310 320 330 340 350 360 NVKREPDGSF YEADHLDGDN DMVGLVNALL CEERRRHAAG ETNCAIPMRP DHGHLMADEL 370 380 390 NLPDVKPGYS YTGRMKGLAE LRGVIHALEV LQRQHAL

References

[1]

"Complete sequence of Saccharophagus degradans 2-40." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Kyrpides N., Lykidis A., Richardson P., Weiner R. Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000282 Genomic DNA. Translation: ABD80535.1.
RefSeq	YP_526747.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q21L94.
Genome annotation databases
GeneID	3965255.
GenomeReviews	Gene locus Sde_1273 in contig CP000282_GR.
KEGG	sde:Sde_1273.
NMPDR	fig|203122.1.peg.3541.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q21L94.
OMA	RPDHGHL.
Enzyme and pathway databases
BioCyc	SDEG203122:SDE_1273-MON.
Family and domain databases
HAMAP	MF_00106. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
TIGRFAMs	TIGR00695. uxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UXUA_SACD2

Accession

Primary (citable) accession number: Q21L94

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	April 18, 2006
Last modified:	November 3, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)