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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyciSDEG203122:G1G67-1788-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:Sde_1691
OrganismiSaccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Taxonomic identifieri203122 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCellvibrionalesCellvibrionaceaeSaccharophagus
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002580941 – 243Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST243

Proteomic databases

PRIDEiQ21K28

Interactioni

Protein-protein interaction databases

STRINGi203122.Sde_1691

Structurei

3D structure databases

ProteinModelPortaliQ21K28
SMRiQ21K28
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102325
KOiK00684
OMAiYRQGIFP
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

Q21K28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPELVWLNPH DTVFPPTTSA LEDPNGLLAV GGDLSPARLI AAYKKGIFPW
60 70 80 90 100
FDDSQPILWW SPDPRMVLLP QNLHLGKTLK KLAKKQAFKI TIDTHFSDVM
110 120 130 140 150
QGCAQPRADQ DGTWITTDME NAYLELHKLG YAHSIEAWQD GELVGGLYGI
160 170 180 190 200
AINRVFYGES MFSKVSGASK IAFANLATQL ASWGFYAIDC QVATEYLASF
210 220 230 240
GAAEMPRVEF EQILQQSLQS QPPKCQIEGW QNSWNMPDYG QLF
Length:243
Mass (Da):27,175
Last modified:April 18, 2006 - v1
Checksum:i5D9DB66251327475
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000282 Genomic DNA Translation: ABD80951.1
RefSeqiWP_011468171.1, NC_007912.1

Genome annotation databases

EnsemblBacteriaiABD80951; ABD80951; Sde_1691
KEGGisde:Sde_1691

Similar proteinsi

Entry informationi

Entry nameiLFTR_SACD2
AccessioniPrimary (citable) accession number: Q21K28
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: April 18, 2006
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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