Q21IS4 (CYSD_SACD2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT

Gene names

Name:	cysD
Ordered Locus Names:	Sde_2145

Organism

Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) [Complete proteome] [HAMAP]

Taxonomic identifier

203122 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Saccharophagus

Protein attributes

Sequence length	303 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 303	303	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_0000340219

Sequences

	Sequence		Length	Mass (Da)
	Q21IS4 [UniParc]. Last modified April 18, 2006. Version 1. Checksum: 7B9F9EE94D19EA23	FASTA	303	35,010
	10 20 30 40 50 60 MLDEYKLTHL KQLEAESIHI IREVAAEFDN PVMLYSIGKD SAVMLHLAMK AFAPGKPPFP 70 80 90 100 110 120 LMHVDTTWKF KEMIEFRDKY VKELGLELIV HSNQEGIDMG ISPFVHGSAK HTDIMKTQAL 130 140 150 160 170 180 KQALDKHGFD AAFGGARRDE EKSRAKERVY SFRDKKHRWD PKNQRPELWN IYNSRVDKGE 190 200 210 220 230 240 SIRVFPLSNW TELDIWQYIH LESIPLVPLY FAAKRPVVER DGTLIMVDDD RMPIEPGEKV 250 260 270 280 290 300 EEKMVRFRTL GCYPLTGAVE SEATTLPEII QEMLLTTTSE RQGRVIDHDS SGSMEKKKQE GYF

References

[1]

"Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 T." Weiner R.M., Taylor L.E. II, Henrissat B., Hauser L., Land M., Coutinho P.M., Rancurel C., Saunders E.H., Longmire A.G., Zhang H., Bayer E.A., Gilbert H.J., Larimer F., Zhulin I.B., Ekborg N.A., Lamed R., Richardson P.M., Borovok I., Hutcheson S. PLoS Genet. 4:E1000087-E1000087(2008) [PubMed: 18516288] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 2-40 / ATCC 43961 / DSM 17024.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000282 Genomic DNA. Translation: ABD81405.1.
RefSeq	YP_527617.1. NC_007912.1.
3D structure databases
ProteinModelPortal	Q21IS4.
SMR	Q21IS4. Positions 6-213.
ModBase	Search...
Protein-protein interaction databases
STRING	Q21IS4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3967529.
GenomeReviews	Gene locus Sde_2145 in contig CP000282_GR.
KEGG	sde:Sde_2145.
NMPDR	fig|203122.1.peg.1110.
PATRIC	23403280. VBISacDeg56404_2313.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
OMA	RRSEREN.
PhylomeDB	Q21IS4.
ProtClustDB	PRK05253.
Enzyme and pathway databases
BioCyc	SDEG203122:SDE_2145-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_SACD2

Accession

Primary (citable) accession number: Q21IS4

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	April 18, 2006
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program