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Q21IH6 (Q21IH6_SACD2) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonuclease 3 HAMAP-Rule MF_00104
EC=3.1.26.3 HAMAP-Rule MF_00104
Alternative name(s):
Ribonuclease III HAMAP-Rule MF_00104
Gene names
Name:rnc HAMAP-Rule MF_00104
Ordered Locus Names:Sde_2243
OrganismSaccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) [Complete proteome] [HAMAP] EMBL ABD81503.1
Taxonomic identifier203122 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Saccharophagus ›

Protein attributes

Sequence length226 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104 SAAS SAAS001159

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104 SAAS SAAS000999

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104 SAAS SAAS001159

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104 SAAS SAAS001159.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain. HAMAP-Rule MF_00104 SAAS SAAS001159

Contains 1 RNase III domain. HAMAP-Rule MF_00104 SAAS SAAS001159

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain4 – 126123RNase III By similarity HAMAP-Rule MF_00104
Domain155 – 22571DRBM By similarity HAMAP-Rule MF_00104

Sites

Active site431 By similarity HAMAP-Rule MF_00104
Active site1151 By similarity HAMAP-Rule MF_00104
Metal binding391Magnesium By similarity HAMAP-Rule MF_00104
Metal binding1121Magnesium By similarity HAMAP-Rule MF_00104
Metal binding1151Magnesium By similarity HAMAP-Rule MF_00104

Sequences

Sequence LengthMass (Da)Tools
Q21IH6 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: 48135BDA30D38A52

FASTA22624,949
        10         20         30         40         50         60 
MNQNDRLVAR LGYTFKDKSL LKLALSHRSY GKQNNERVEF LGDSLLNFII AEALFAKFPT 

        70         80         90        100        110        120 
AKEGQLTQLR ANLVKGETLA EIAREFGLGD FLLLGEGELK SGGFRRASIL ADAVEALIGA 

       130        140        150        160        170        180 
IYLDSNSSMP TCRERVLAWY ATRLDKVELK ATAKDAKTLL QEYLQERKMP LPTYTVLAEG 

       190        200        210        220 
GEAHSRQFTV ECTITGKSKP CSAVGNSKRI AEKLAAEKML SQLTNA

« Hide

References

[1]"Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 T."
Weiner R.M., Taylor L.E. II, Henrissat B., Hauser L., Land M., Coutinho P.M., Rancurel C., Saunders E.H., Longmire A.G., Zhang H., Bayer E.A., Gilbert H.J., Larimer F., Zhulin I.B., Ekborg N.A., Lamed R., Richardson P.M., Borovok I., Hutcheson S.
PLoS Genet. 4:E1000087-E1000087(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2-40 / ATCC 43961 / DSM 17024.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000282 Genomic DNA. Translation: ABD81503.1.
RefSeqYP_527715.1. NC_007912.1.

3D structure databases

ProteinModelPortalQ21IH6.
ModBaseSearch...

Protein-protein interaction databases

STRING203122.Sde_2243.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD81503; ABD81503; Sde_2243.
GeneID3964847.
KEGGsde:Sde_2243.
PATRIC23403490. VBISacDeg56404_2417.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHOG000246809.
KOK03685.
OMARACELPR.

Enzyme and pathway databases

BioCycSDEG203122:GI2M-2281-MONOMER.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR001159. Ds-RNA-bd.
IPR014720. dsRNA-bd-like_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. RNase_III. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ21IH6_SACD2
AccessionPrimary (citable) accession number: Q21IH6
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: May 29, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info