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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSDEG203122:G1G67-2509-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Sde_2379
OrganismiSaccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Taxonomic identifieri203122 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaCellvibrionalesCellvibrionaceaeSaccharophagus
Proteomesi
  • UP000001947 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420861 – 579Arginine--tRNA ligaseAdd BLAST579

Proteomic databases

PRIDEiQ21I40

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi203122.Sde_2379

Structurei

3D structure databases

ProteinModelPortaliQ21I40
SMRiQ21I40
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q21I40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIRNLLNDR VKSAMNDAGI PADYSPHLAV SKKAGFGDYQ ANGAMGAAKA
60 70 80 90 100
LKTNPREVAQ KIIDNLDLNG IASKVEIAGP GFINIHLDPK WLAQQTVAVT
110 120 130 140 150
NSTNLGILPK NNPETVVIDY SSPNLAKEMH VGHLRSTIIG DAIARVLEFT
160 170 180 190 200
GDKVIRQNHV GDWGTQFGML IAELEDQLGS GERPELALQD LEGFYQQAKK
210 220 230 240 250
HFDDDPAFAD RARDYVVKLQ SGDAQVNKLW QEFRRVSLLH AEEIYRKLNV
260 270 280 290 300
TLGEADVRGE SAYNDDLAPV VAELEAQGLA VEDQGAKVVF LHELADKNGD
310 320 330 340 350
PSVAIIQKKD GGYLYSTSDL AALRYRVGTL KANRILYFID ARQSLHMQQV
360 370 380 390 400
FTLARKAGFA DEWLSTEHHA FGTMLGSDGK PFKTRSGGTV KLAQLLDEAV
410 420 430 440 450
ERAAKEVRTK NPDLTEEEMA EVASKVGIGA VKYADLCKTR TNDYVFNWES
460 470 480 490 500
MLAFEGNTGP YMQYAYTRIR SIFRRANENM DTFESEVNLT EPQEVQLAIK
510 520 530 540 550
LLQLPEIVEQ IAADAYPHVM CNYLYDLASL FMTFYEACPI LKEGVEPAVK
560 570
TSRLQLSKGV ARTLAQGLDL LGIEVMEKM
Length:579
Mass (Da):64,165
Last modified:April 18, 2006 - v1
Checksum:i2BDFEF9FCC4E6BC9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000282 Genomic DNA Translation: ABD81639.1
RefSeqiWP_011468856.1, NC_007912.1

Genome annotation databases

EnsemblBacteriaiABD81639; ABD81639; Sde_2379
KEGGisde:Sde_2379

Similar proteinsi

Entry informationi

Entry nameiSYR_SACD2
AccessioniPrimary (citable) accession number: Q21I40
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: April 18, 2006
Last modified: May 23, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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